Questions tagged [vaccination]

Use this tag for questions related to the development, administration, or monitoring of a treatment intended to produce immunity against a communicable disease.

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BNT162b2 mRNA Covid-19 Vaccine efficacy after 1st dose - explain the statistics

Pfizer's paper (Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine) published recently states the following in the Efficacy subsection of the Results section: Between the first dose and the ...
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13 votes
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Was there ever a vaccine candidate that showed negative side effects many months or years after the patient was injected?

The current prognosis for a COVID-19 vaccine to become available is "12-18 months" and a big part of the reason for such a long timeline is the fact that scientists want to ensure that the vaccine is ...
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7 votes
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How do mRNA vaccines work and what are their advantages over traditional vaccines?

How do mRNA vaccines work? To my intuitive understanding, for an mRNA vaccine to work, the mRNAs injected into the patient need to first enter a cell and get translated into proteins. Those proteins ...
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2 votes
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Details on "Health Impact Events" on V-safe Active Surveillance for COVID-19 Vaccines

Some dubious websites (which I won't link) are claiming that COVID-19 vaccine caused disabilities in more than 3.000 people. As a support of this claim, they cite the table "V-safe Active ...
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4 votes
3 answers
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Is there a benefit of a COVID-19 vaccination if one had COVID-19 before?

I see the clear benefit of the vaccination if one didn't have the disease. However, there are a lot of people who had the disease already. So I assume they also have the anti-bodies? Or is this a ...
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10 votes
2 answers
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Why is the new mRNA vaccine unable to modify human DNA?

One of the most common worries expressed against the new coronavirus vaccine is that, supposedly, injecting mRNA into a cell has the potential to alter the human genome. I am constantly bombarded by ...
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Is there evidence that vaccine-related blood clots could be due to injection technique?

Recently, Danish health authorities including Denmark's SSI issued new guidelines for intramascular vaccination to be done with aspiration, in case some of the vaccine-induced blood clot cases are due ...
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7 votes
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COVID-19 vaccination second doses: why two doses and why the specified interval?

Certain COVID-19 vaccines such as the Pfizer BioNTech and Moderna are specified to be administered in two doses separated by a 21 and 28 day interval, respectively. My questions are: Why administered ...
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What are the limits on the amount of pathogens that a body can be immune to at any given time?

Before the seasonal flu vaccine was recommended for all healthy adults, people in developed countries might get vaccinated against on the order of 10 different pathogens and develop immunity for some ...
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4 votes
1 answer
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Is a general vaccine against getting a cold possible?

While the common cold is a broad disease, is it possible to get vaccinated? Is it possible at least in some future, or is it even in theory not possible?
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1 answer
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Why use sucrose rather than glucose in an injectable vaccine?

These are the ingredients of Pfizer-BioNTech COVID-19 vaccine: Medicinal: mRNA Non-medicinal: ALC-0315 = ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate) ALC-0159 = 2-[(...
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3 votes
1 answer
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Is the code from the mRNA vaccine executed by the cells as a one-off? [closed]

Is the code from the mRNA vaccine executed by the cell that has taken it up as a one-off or does the cell produce the spike proteins endlessly (like a programming loop) until the cell is killed by the ...
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3 votes
2 answers
195 views

Why will COVID-19 last for 12 to 18 months?

In this YouTube video min 0:32, Dr. Samir Gupta, says It typically would last for 12 to 18 months In How the Pandemic Will End in the ll. The Endgame section: No matter which strategy is ...
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2 votes
1 answer
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what does 95% effectivenes mean for vaccines (covid) [duplicate]

Often we see in news they say AstraZeneca is 95% effective, while Chinese vaccine is 50%. I have question how to interpret these numbers. Does this mean that if you get vaccinated with AstraZeneca ...
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1 answer
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Do vaccinated people not have zero risk of mortality by Covid 19?

This video by Vox says people who are vaccinated have zero risk of mortality by Covid 19. But NDTV reports (at 00:21 and again at 07:53 in the video) that even fully vaccinated 8 frontline medical ...
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22 votes
3 answers
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How many people end up needing medical attention during the 15 minute window after receiving the Pfizer vaccine?

Everyone receiving the COVID vaccines is asked to wait for 15 minutes in case they have a bad reaction to the shot. Given that we've now had hundreds of millions of Pfizer vaccine shots injected ...
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10 votes
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Are Covid-19 vaccines much more deadly than people (and scientists) think?

The other day I read this chart on an Italian newspaper article I looked for the source, and I found only this tweet: https://twitter.com/Drs4CovidEthics/status/1432193260949172230 from Doctors for ...
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1 answer
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Does antigen expression from an mRNA vaccine damage the host cell?

When mRNA (from a vaccine) enters a cell and the transcription process gets underway, the host cell effectively becomes an antigen factory. How does the antigen leave the cell so that it can trigger ...
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9 votes
1 answer
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3 Injections for Hep B Vaccine

It has been suggested by my employer that i should get the Hepatitis B vaccine to protect myself. I have had two of the three parts, but this is the first time i have had a vaccine in more than one ...
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Is there a disease where having had the disease provides less protection for the future than the vaccination?

Vaccination makes sure that you have anti-bodies so that your immune system has a heads-start once you get infected. If you were infected before, your body also built anti-bodies. Are there diseases ...
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3 votes
1 answer
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Flu vaccine paradox [closed]

Here are two facts that one clearly admit and and almost read everywhere: Fact 1) it needs many years to elaborate a vaccine (from research, creation, testing and approval) Fact 2) new vaccine for ...
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2 votes
1 answer
273 views

Why are some viruses harder to make vaccines for?

A number of common viral disease agents have vaccines produced for them: Hepatitis B, Diphtheria, Influenza (flu), Varicella (chicken pox), Poliovirus (polio), and many more. But many very serious or ...
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3 answers
262 views

Covid-19 spike protein as vaccine?

The genome of Covid-19 was mapped in early Feb. The gene for a protein spike was used to produce these spike proteins. 3-D microscopy of this synthesized spike has been produced. Quoting McLellan from ...
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9 votes
2 answers
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Are there diseases for which infection does not grant lasting immunity but a vaccine does?

There has been a lot of discussion about whether people who have COVID-19 and recover will have long-lasting immunity. At the same time, work is underway to create a vaccine for this disease. But if ...
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Can getting the flu shot make you sicker next year?

During college I faithfully got my flu vaccine every year. Shortly after I left college the US had a year with a bad flu vaccine shortage (2004). When discussing the shortage with my coworkers at ...
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6 votes
1 answer
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Best type of flu shot

This October I am going to new Doctor who is close to my home. Old Doctor passed away. I went to CDC website and it lists many type of flu shots http://www.cdc.gov/flu/protect/vaccine/vaccines.htm ...
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3 votes
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Would being infected with every kind of cold virus strain at once be a good immunization or dangerous?

I know colds come from around 200 different kinds of viruses. https://en.m.wikipedia.org/wiki/Common_cold But would it be worth the risk to be purposefully infected with every type of strain that ...
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2 votes
1 answer
46 views

Are there vaccines which present a risk by being re-taken too early?

A friend of mine lost the vaccination information for one of his children (a 15 yo boy) and has doubts about the date for the next shot against tetanus (which in France comes together with the ones ...
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1 vote
1 answer
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Where is the data for Covid-19 vaccine safety in medium term and/or for people with chronic health conditions?

I have several middle-aged relatives which are... let's say postponing their vaccination due to fears of their safety. Now, I know there are some people who will never be convinced by anything, ...
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1 vote
1 answer
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How does getting 2 or 3 shots of the Pfizer or Moderna COVID vaccine compare against 1 shot Johnson & Johnson's vaccine + 1 shot of Pfizer or Moderna?

I wonder how does getting 2 or 3 shots of the Pfizer or Moderna COVID vaccine compare against 1 shot Johnson & Johnson's vaccine + 1 or 2 shots of Pfizer or Moderna, in terms of COVID-19 ...
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1 vote
1 answer
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Are there any epidemiological or laboratory studies on the effectiveness of variolation?

Variolation has been brought up in some circles nowadays as a proposal to deal with the Covid-19 crisis (sometimes by invoking the glorious/revolutionary American past). Looking at the aforementioned ...
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0 votes
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Vaccine efficacy to get FDA approval

What is the required efficacy level for a COVID-19 vaccine to get FDA approval? I heard the numbers 50% and 60% - but can not find any document which would explicitly say so. My concern is that two ...
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-1 votes
1 answer
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For fighting COVID19, Why we give the body the RNA and not give the body the protien itself? [duplicate]

If I understand things correctly the popular COVID 19 vaccine gives the body RNA that teaches the body cells to create a protein that looks like the virus. And then the body learns to fight against it....
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