Questions tagged [side-effects]

Questions about secondary or unwanted effects a drug can cause on a person; ie: how depression medication can cause suicidal thoughts.

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42 views

What are the concrete odds of myocarditis in using Modena vs Pfizer vaccine, according to the Nordic agencies' data/studies?

It's been reported that some Nordic countries have suspended the Moderna vaccine from younger age groups, due to an increased incidence of myocarditis, seemingly relative to Pfizer. However, even ...
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47 views

What data supports the safety of COVID-19 mRNA vaccines for women of childbearing age?

I am looking for the actual data (ie, numbers) supporting the widespread consensus regarding the safety of the COVID-19 mRNA vaccines with regards to fertility, pregnancy, and childbirth, as stated ...
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Covid vaccine second dose side effects and immunity

Does experiencing side effects such as fever/headache/muscle ache after the second dose of vaccine mean that immune system is weak and catching covid would have been more dangerous in comparison to ...
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Immunoglobulin E (IgE) level and covid vaccine

I am finding hard to find information if a person has say higher than average level of Immunoglobulin E (IgE) is it safe to do covid vaccine?
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Why nutritional / Dietary supplement pills are having their side effects?

I was recently reading about nutritional or dietary supplement medicines or pills most of them contain wide range of vitamins and minerals essential for well being of a human being and are used to ...
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25 views

If you've already been infected with SARS-CoV-2, do the vaccines cause fewer side effects?

Assuming that I had Covid-19 not so long ago. My body should have produced some type of antibodies to defend against the infection*. If I now get one of the vaccines, would it be more likely that ...
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Why there is histamine release following d-TC administration?

Skeletal muscle relaxants (specifically Isoquinoline derivatives like d-Tubocuriarine) liberate Histamine from Mast cells. Ref: https://pubmed.ncbi.nlm.nih.gov/2581878/ What is the mechanism of this ...
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43 views

Why isn't there a hormonal therapy specific to the treatment of PCOS?

Women with Polycystic Ovarian syndrome are commonly prescribed oral contraceptives for the reducing effect of anti-androgens on symptoms such as acne and hirsutism. I don't have great medical ...
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Why do pseudoephedrine and methamphetamine have such different pharmacological effects despite only a difference in one oxygen molecule?

Pseudoephedrine's formula is: C10H15NO and methamphetamine's is: C10H15N. The only differ by an oxygen molecule yet have different effects. The reason I ask is because I have a relative in the States ...
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62 views

How effective is sinovac/sinopharm vaccine

it's time for me to get vaccinated with sinovac vaccine. I am actually a little bit nervous, about its effectiveness, I am not a docotor and I have no idea what's behind it. I am worrying that it ...
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Were thrombocyte counts or bleeding events monitored at all during ChAdOx1 (AZD1222) clinical trials?

Maybe I'm just missing something, but on a quick look, I find it a bit strange that since issues with thrombocyte (platelet) counts in adenovirus-vectored therapeutics have (1) been known for about ...
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Can growth hormone treatment affect body proportions?

I am thinking especially of abnormally short legs in proportion to the trunk for an average height. Could this be a side effect of growth hormone treatment in childhood?
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Muscarinic receptors in bladder

ACh contracts the wall of the bladder(by M3 receptor). How does it relax the sphincter?
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Which is the best test to confirm a Lidocaine allergy?

As per my study, there are two tests which are performed to confirm/dispute a Lidocaine allergy. Patch test Intradermal Test Which is the most conclusive of the above? Are there any other tests?
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Are side effects of corona virus vaccines no worse than virus symptoms?

In my country there is a general fear for side effects of the Pfizer and Astrazeneca vaccines, also due to some deaths among people having taken the vaccine. I reason that since the vaccines replicate ...
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252 views

Can COVID-19 vaccines cause birth defects?

Have regulators historically allowed enough time for Phase 3 trials to show that a vaccine does not cause congenital defects? Are they making an exception for Covid vaccines? Because the Pfizer/...
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Why is the new mRNA vaccine unable to modify human DNA?

One of the most common worries expressed against the new coronavirus vaccine is that, supposedly, injecting mRNA into a cell has the potential to alter the human genome. I am constantly bombarded by ...
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Are there any educated guesses related to the type and probability of severe side effects caused by the COVID-19 vaccines?

Multiple countries have already started the COVID-19 vaccination. Local media covered this extensively and I saw that many medical doctors and researchers arguing that the vaccines are very safe ...
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Covid vaccine side effects [closed]

The Pfizer Covid vaccine caused allergic reactions. For patients that are deemed to be at an increased risk of adverse side effects following a risk assessment (e.g. because of diabetes, heart disease)...
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50 views

How frequently does the use of topical fluorouracil cream result in permanent scarring and/or skin discoloration?

I wonder how frequently the use of topical fluorouracil cream results in permanent scarring and/or skin discoloration (e.g., hyper- or hypopigmentation). What I have found so far doesn't give any ...
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How frequently does the use of topical imiquimod result in permanent scarring and/or skin discoloration?

I wonder how frequently the use of topical imiquimod cream results in permanent scarring and/or skin discoloration (e.g., hyper- or hypopigmentation). What I have found so far doesn't give any source ...
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82 views

Is calling dexamethasone a "psychoactive steroid medication" correct use of the term psychoactive? Because it has reported psychological side effects?

Pete Buttigieg has a decent educational and professional background and good command of the English language and some appreciation for facts, which is why I call this choice of words into question and ...
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A Good Side Effect of Zoloft? [closed]

I’m a 70-year-old male. I had been using eyeglasses since I was 12 and near-sighted (eventually reaching 20/400 by the time I was 18), and needed bifocals at about 50 y.o. About 20 years ago I started ...
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corona virus vaccine side effects [closed]

First I like to mention that I have no medical background I have read that there are 2 types of vaccines for the corona virus currently developed A RNA based vaccine, which is based on a novel ~...
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Does sulfasalazine share other positive or negative effects associated with aspirin due to its salicylate component?

tl;dr: The common drug sulfasalazine "...should not be used in people allergic to aspirin..." because it contains salicylate. Is it known to share other positive or negative effects ...
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Intravenous morphine as painkiller for woman in labor and possible side effects in the newborn

If an intravenous morphine injection is given as a painkiller to a pregnant woman during childbirth, what side effects should we look out for in the newborn, and if so, what should we do for the baby?
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What are the long term effects of Lidocain injections to treat a tendinopathy?

Lidocain injections are often regarded as a potential replacement for corticosteroid injections, as the latter have been demonstrated to weaken tendons in the long-term (> 6 months). What are the ...
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172 views

How does amiloride increase calcium reabsorption in the kidneys?

Amiloride is a potassium-sparing diuretic that acts on the distal convoluted tubule and collecting ducts to inhibit ENaC channels. I found studies that show that this drug increases calcium ...
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Was there ever a vaccine candidate that showed negative side effects many months or years after the patient was injected?

The current prognosis for a COVID-19 vaccine to become available is "12-18 months" and a big part of the reason for such a long timeline is the fact that scientists want to ensure that the vaccine is ...
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Other than death, what are the potential long-term health impacts on individuals infected with COVID-19?

There is a lot of concern about deaths resulting from or exacerbated by SARS-CoV-2 infections, but I can find little about the potential long-term health impacts on those who 'recover' (understandably,...
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38 views

Is there a greater benefit as as to why an ob-gyn will prescribe a birth control with higher risk of Venous Thromboembolism?

It is already known that combined oral contraceptive (COCs) pills increase the risk of serious complications such as Venous Thromboembolism. However there are other options that have relatively much ...
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2answers
271 views

Why is it that psychoactive drugs tend to be dangerous?

I'm personally not a big fan of recreational drugs, illicit or otherwise, but there's an interesting medical question buried in their use. Why is it that substances that make you feel good tend to be ...
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Why isn't paracetamol routinely combined with n-acetylcysteine?

Whether it's acute large dose paracetamol or long term regular dosage of paracetamol usage, it is a problem for the liver, ototoxic and even potentially life-threatening. While one might question the ...
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47 views

Is there a measure for the severity of adverse effects of a medication?

When I search for the adverse effects of medications, what I usually find is a list of effects and their occurance rate. But it's evident that different medications cause adverse effects with ...
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Is it possible for a specific brand of a vaccine (for Leptospirosis in dogs) to cause hepatic side effects?

I am a veterinarian in Europe and I am facing an unusual case. Within the last month, I have seen two different young dogs (3 years and 4 years old) to whom I administered a tetravalent vaccine for ...
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37 views

Longterm effects on DNA of aciclovir

Since aciclovir works by decreasing the production of the virus's DNA, one might fear that it also damages DNA of healthy cells. I know that it is usually said that aciclovir doesn't affect healthy ...
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Why does acne get worse during the first two weeks of treatment with isotretinoin?

I've heard and read from multiple sources that acne gets worse during the first two weeks of treatment with isotretinoin, but I haven't been able to find an explanation as to why this happens. From ...
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2k views

Does ecdysterone supplementation have any deleterious side effects?

Ecdysterone supplementation has been shown to have a significant anabolic effect {1}: Significantly higher increases in muscle mass were observed in those participants that were dosed with ...
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Why would ECT be done without anasthesia?

In the ending of Requiem For A Dream. The grandma gets ECT after using "Rainbow Pills" for weight loss. The most horrifiying part is. The whole procedure is done while She is awake. The original ...
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Does longer oil pulling than recommended 20 minutes bring any benefits?

EDIT. I am looking for references to serious research articles on the subject, whether confirming or refuting. (Or articles referring to such, but not articles without peer refereed references.) To ...
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207 views

Frequency of drug side effect listed as "unknown"

I'm looking at the side effects of Madopar, and all of them are listed as "unknown frequency". How can frequency be unknown? Even if just one of a million patients got a certain side effect, that ...
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190 views

Can excessive Vitamin D cause insomnia or damage sleep patterns?

It seems its well known that low vitamin D can cause sleeping issues, one link: https://examine.com/nutrition/can-supplemental-vitamind-improve-sleep/ Therefore, I became curious and was wondering ...
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85 views

Can zinc (over)supplementation cause hypocalcemia?

From Wikipedia's article on hypocalcemia (version dated 27 Nov 2018): Causes: ... Excessive dietary zinc, as with supplementation (causes rapid hypocalcemia) I googled but found no studies ...
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Arthropathic effects of trientine dihydrochloride treatment?

I've been Googling for the effects of long-term usage of trientine as a treatment for Wilson's disease and could find none. My mom's had Wilson's disease for over 40 years now (she was diagnosed way ...
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118 views

Are auditory hallucinations a side effect of Oxycodone? How long does Oxycodone stay in the body?

Are auditory hallucinations a side effect of Oxycodone (when used for a short period following a surgery)? To give this question context, the following situation has been provided (not to be ...
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Can removing a contraceptive implant cause secondary amenorrhea?

When a woman stops taking birth control medication, she might suffer from various side effects. Can secondary amenorrhea (i.e. missing periods for more than 3 months) be induced by the removal of a ...
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112 views

Are aluminum profiles dangerous?

I am thinking about building racing rig from aluminium profiles. Something like this: Original image here: http://www.simracingmachines.com/images/builds/rig2014/IMG_1686s.jpg I would like to have ...
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80 views

How to reduce the side effects of wearing contact lens? [closed]

This explains a lot of side effect of wearing contact lens. The type of contact lens Iam talking about is silicon hydrogel lenses. Questions: 1) Till how many hours can lens be worn continuously? 2)...
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61 views

Why is it that some medicines "may" cause a side effect?

For example, take the drug diphenhydramine. The website says that "Diphenhydramine is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms." ...
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Imazalil on citrus fruits

Imazalil is a fungicide, dangerous for our health. Widely used in agriculture, e.g. you can find Imazalil on lemons. But it's no clear at all to me if risks are associated with eating, breathing, ...