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Questions tagged [pharmacokinetics]

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2 votes
1 answer
96 views

How to estimate equivalent doses of similar medicines with different route of administration?

I am trying to compare the two medications used as rescue medications for seizures 5mg Rectal Diazepam 2.5mg Buccal Midazolam (Buccolam) I am aware that Midazolam is considered to be more potent than ...
2 votes
0 answers
78 views

Are there medications that treat premature ejaculation without interfering in serotonin levels?

The widespread medications that are being used to treat premature ejaculation (PE) are kind of antidepressants called SSRIs (Selective Serotonin Reuptake Inhibitors). But the problem with this kind of ...
4 votes
0 answers
57 views

Do topical anti-inflamatory preparations work topically?

There are topical anti-inflamatory preparations where the advertising at least implies that they work topically, in that the effect will be more localised by the use of a topical preparation than if ...
4 votes
1 answer
103 views

Would slight shifting of administration times of Paxlovid impact its efficacy?

Paxlovid (nirmatrelvir/ritonavir) is an oral medication indicated for patients recently diagnosed with COVID-19 and who are at high risk of deterioration. This drug received an emergency use ...