Questions tagged [pathophysiology]

The biochemical, molecular, and physiologic mechanisms that cause disease.

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Mechanisms that causes prominent veins during physical exercise

I have just read this article about why veins become prominent while exercising: Why do veins pop out when exercising, and is that good or bad? I have some questions about this: The article ...
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Why oligohydramnios leads to hypoplasia of lung?

What I found for the question is that due to - Oligohydramnios reduces the intrathoracic cavity size, thus disrupting fetal lung growth and leading to pulmonary hypoplasia. decreased fetal breathing ...
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English-language term for “productive vasculitis”

I'm translating a Russian text that gives a description of necropsy results. It mentions "productive vasculitis": Сосуды вокруг участка гранулематозного воспаления с признаками продуктивного ...
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40 y/o woman admitted with ARDS but normal values

Second year medical student asking: A 40 year old woman is admitted to the ICU with acute respiratory distress syndrome due to a life threatening case of pneumonia. Her respiratory values are as ...
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32 views

What is the difference between lipohyalinosis and microatheroma?

Lacunar strokes (small-vessel subcortical strokes) are commonly caused by "lipohyalinosis" or "microatheroma"(1). Both mechanisms appear to be related to hypertension and diabetes, ...
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Why proximal muscle weakness improves in Lambert- Eaton syndrome with isometric contraction?

Lambert Eaton has antibodies to presynaptic calcium VGC(voltage gated channel). So how does doing an isometric (or any other type of contraction) will improve weakness, what will be pathophysiology? ...
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What happens to ICF in primary aldosteronism?

There is contradictory information in my two textbooks, As per Kaplan Physiology 2018, There is gain of isotonic fluid, because aldosteronism cause Na+ retention and water follow, so osmolality ...
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37 views

Atlas of pathology / morbid anatomy. Is there any?

Is there any atlas which have Human's fresh pathological gross specimen with their segmental cut-sections of different tissues? Why fresh! the reason is after embalming any tissues, organs changes ...
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Do people from sunnier parts of the world show accelerated aging?

A lot of medical evidence seems to point to there being a link between sun exposure and skin aging. Would this mean that on average, a 30-year-old from Arizona would have more wrinkles and uneven skin ...
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29 views

What mechanisms of action plausibly explain the correlation between SIBO and a CRC?

Doctors who treat gut conditions have found that Small Intestinal Bacteria Overgrowth (SIBO) and Candida-Related-Complexes (CRC) often occur in the same people, but as far as I am aware, which, if ...
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17 views

Food diary as diagnostic aid

If I was interested in cataloguing eating habits for the purpose of shedding light on what seems to be a bowel disorder or dysfunction caused primarily, but not exclusively, by ingested food (or the ...
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41 views

Is vitamin D a very passive xenogenic factor to major depressive disorder?

Are the biosynthesis, utilisation and catabolism systems of vitamin D, especially the pathways of neural cells' vitamin D response, altered by the pathophysiological condition of major depressive ...
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Meningeal irritation in subarachnoid hemorrhage

Meningeal irritation, as indicated by features such as neck stiffness, is a common finding during subarachnoid hemorrhage. However, its pathophysiology is rather unclear to me. In particular, I do not ...
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12 views

The Roles of SSRIs and Neurotransmitters in Migraines

How do SSRIs alleviate migraine pain? Can anyone shed any light into the mechanism please? More broadly, I am interested in the roles of neurotransmitters in the cause and potential prevention of ...
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35 views

What specific factors give rise to the mortality rates depending on cancer type?

In my experience it is commonly communicated that certain types of cancer have a higher rate of mortality than others. For instance1, pancreatic cancer has a very poor prognosis while the prognosis ...
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Seeking a translation for Russian “геморрагический венчик” (hemorrhagic crown?), a feature observed in an infarct

According to the Russian classification of infarcts, По цвету инфаркт может быть белым (селезенка, головной мозг), белым с геморрагическим венчиком (сердце, почки) и красным (геморрагическим). ...
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Cavocaval anastomosis via vv. epigastrica superficiales et thoracoepigastrica

(I ask you to pardon me for wrong terms because I am not studying medicine in english) I've read that the v. porta superior is connected with the v. porta inferior via a cavocaval anastomosis through ...