Questions tagged [organ-transplant]

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Why does a bone marrow transplant recipient need to match their donor if their own immune system is going to be entirely replaced?

I am new here at Medical Science SE (first ever question!) and perhaps I sound like an idiot, but... Why (or how) would a bone marrow transplant recipient's native immune system attack the new bone ...
Kurt Hikes's user avatar
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What advances have been made in liver transplants in the past 30 years?

Imagine someone needing a liver transplant 30 years ago versus today. What advances have been made to make the procedure safer now? My research I know that the constant in all organ transplants has ...
Rohit Pandey's user avatar
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Is black spotting on the lungs a common benign variance, or a sign of pathology?

I recently found this article which shows an externally-healed lung donation before transplant. The left image is supposedly the lung pre-treatment, and right is post. In both of these images, black ...
jamesdlivesinatree's user avatar
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What is the mechanism of immune privilege that prevents immunological damage in some organs?

I was reading about immune privilege in a paper called Immune Privilege of Heart Valves by Hill et al. Immune privilege is summarised as follows: Immune privilege is an evolutionary adaptation that ...
Chris's user avatar
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Transplant in combination with stem cell transplant

I was wondering, if you transplant a kidney from person A to person B and combine it with a stem cell transplant, would you then need no/less immunosuppressive drugs? Since you would have an antibody ...
Hester's user avatar
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Effects of Garlic on Tacrolimus via CYP3A4

Garlic is said to be an inducer of CYP3A4, Tacrolimus is metabolized by CYP3A4. The list of drugs (and some foods) interacting with Tacrolimus is long but nowhere I found a note on garlic. Grapefruit ...
Llarian's user avatar
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What could cause a stroke soon after a lung transplant? Is it even known?

Recently a youtuber died of a thrombotic stroke a week after a lung transplant operation. Skimming over abstracts on Pubmed, it appears that strokes and more generally thrombosis is a frequent ...
BatWannaBe's user avatar
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What is the longest kidney-exchange cycle yet?

What is the longest kidney-exchange cycle yet? I.e. the longest cycle of simultaneous surgeries "donor1-recipient2-donor2-recipient3 ... donorXX-recipient1" I am preparing a lecture on the Roth-...
Slepecky Mamut's user avatar