Questions tagged [nsaids-pain-meds]

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2
votes
2answers
152 views

Preventing NSAID-associated GI bleeding

Are there ~simple means to reduce risk of GI (gastro-intestinal) bleeding associated with NSAIDs (non-steroidal anti-inflammatory drugs)(ie aspirin) - besides the common-sense answers?: Take with ...
0
votes
0answers
35 views

Why aspirin dose is reduced in gastric achlorydia?

Aspirin remains in unionised form in acidic $pH$ but this unionised form is a diffusible form which is helpful in absorption across lipid membrane. My reasoning almost tries to contradict the ...
7
votes
3answers
107 views

Do NSAIDs “Relieve Pain” or is it a Byproduct?

NSAIDs work by inhibiting the activity of cyclooxygenase enzymes (COX-1 and/or COX-2). In cells, these enzymes are involved in the synthesis of key biological mediators, namely prostaglandins which ...
4
votes
1answer
86 views

Why isn't Tylenol safe?

I've heard people say that Tylenol is safe but many of us think that its safe maybe because its easily available but, what are the risks associated with Tylenol (acetaminophen/paracetamol)?
3
votes
3answers
96 views

At what daily dose does daily aspirin use become dangerous for a long-term user?

Many people take 80-300mg a day of aspirin for cardiovascular reasons; while, from what I've seen online, arthritis patients take up to 3000mg a day (is this correct?). But what are the increased ...
3
votes
2answers
58 views

Is it safer to take Naproxen once a day or twice a day?

Given the choice of taking 500mg of Naproxen once a day, or 250mg of Naproxen twice a day (separated by ~12 hours), which is safer for the kidneys and liver?
2
votes
1answer
370 views

Can ibuprofen and paracetamol be taken together?

I have a headache I've been meaning to get rid of this morning. I do know the differences between paracetamol and ibuprofen however since I just woke up this morning with my thoughts still cloudy, I'...
2
votes
1answer
191 views

Baby aspirin interaction with other NSAIDs

Baby Aspirin (ASA 81 mg) commonly prescribes as a cardiovascular protective agent because of its unique antiplatelet effect. NSAID-NSAID interaction is a famous well known interaction.1 2 3 My ...
4
votes
1answer
67 views

Safe alternatives to painkillers/nsaid?

So recently I have started a new job, and a common thing in the last few weeks is I have been getting headaches occasionally, that will last the rest of the day. The issue is, I workout right after ...
2
votes
1answer
119 views

Do painkillers cure headaches or just stop us from feeling it?

I'm sorry if this is an obvious question. I frequently have migraine attacks, and have to take some pills to stop the pain. Now my question is, does a pill stop the source of an attack, or does it ...
2
votes
1answer
119 views

How to decide which painkiller to take?

This is a dilemma I find myself in every time I'm in need of a painkiller: should I take paracetamol (acetaminophen), ibuprofen or aspirin? I've come across several articles outlining the differences ...