Questions tagged [nsaids-pain-meds]

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Could NSAIDs lift bilirubin level?

If one takes 800 to 1200 mg of ibuprofen a day for 3 to 4 weeks, could that lift total bilirubin level to around 28 micromole/litre and direct bilirubin to around 8 micromole/litre?
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57 views

Why do corticosteroids have few kidney-related side effects?

Prostaglandins are involved with promoting various renal functions. Therefore, NSAIDs, like indomethacin which inhibits protaglandin formation through COX enzyme inhibition, tend to have many side-...
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1answer
39 views

Do NSAIDs (specifically Naproxen) help facilitate the passage of kidney stones?

A patient comes to the pharmacy and says that the doctor prescribed her with Naproxen for her kidney stones, and said that it is not only going to reduce pain, but it will also facilitate the passage ...
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29 views

Why is Toradol no longer available in the US?

A few years ago I was given Toradol for kidney stone pain. It was magical. My friend just had a kidney stone and was given morphine, then Dilaudid. Curious about the differences, I went googling, only ...
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2answers
162 views

Preventing NSAID-associated GI bleeding

Are there ~simple means to reduce risk of GI (gastro-intestinal) bleeding associated with NSAIDs (non-steroidal anti-inflammatory drugs)(ie aspirin) - besides the common-sense answers?: Take with ...
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3answers
112 views

Do NSAIDs “Relieve Pain” or is it a Byproduct?

NSAIDs work by inhibiting the activity of cyclooxygenase enzymes (COX-1 and/or COX-2). In cells, these enzymes are involved in the synthesis of key biological mediators, namely prostaglandins which ...
4
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1answer
90 views

Why isn't Tylenol safe?

I've heard people say that Tylenol is safe but many of us think that its safe maybe because its easily available but, what are the risks associated with Tylenol (acetaminophen/paracetamol)?
3
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2answers
62 views

Is it safer to take Naproxen once a day or twice a day?

Given the choice of taking 500mg of Naproxen once a day, or 250mg of Naproxen twice a day (separated by ~12 hours), which is safer for the kidneys and liver?
3
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3answers
101 views

At what daily dose does daily aspirin use become dangerous for a long-term user?

Many people take 80-300mg a day of aspirin for cardiovascular reasons; while, from what I've seen online, arthritis patients take up to 3000mg a day (is this correct?). But what are the increased ...
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1answer
129 views

Do painkillers cure headaches or just stop us from feeling it?

I'm sorry if this is an obvious question. I frequently have migraine attacks, and have to take some pills to stop the pain. Now my question is, does a pill stop the source of an attack, or does it ...
3
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1answer
145 views

How to decide which painkiller to take?

This is a dilemma I find myself in every time I'm in need of a painkiller: should I take paracetamol (acetaminophen), ibuprofen or aspirin? I've come across several articles outlining the differences ...
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1answer
71 views

Safe alternatives to painkillers/nsaid?

So recently I have started a new job, and a common thing in the last few weeks is I have been getting headaches occasionally, that will last the rest of the day. The issue is, I workout right after ...
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1answer
193 views

Baby aspirin interaction with other NSAIDs

Baby Aspirin (ASA 81 mg) commonly prescribes as a cardiovascular protective agent because of its unique antiplatelet effect. NSAID-NSAID interaction is a famous well known interaction.1 2 3 My ...
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1answer
528 views

Can ibuprofen and paracetamol be taken together?

I have a headache I've been meaning to get rid of this morning. I do know the differences between paracetamol and ibuprofen however since I just woke up this morning with my thoughts still cloudy, I'...
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283 views

Are there any untoward synergistic effects in taking a combination of acetaminophen plus ibuprofen?

A number of years ago, it became popular to advocate a combination of acetaminophen and ibuprofen (or other non-steroidal anti-inflammatory medication) at the usual higher doses — e.g., 1,000 mg ...