Questions tagged [metformin]

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Should Metformin be taken before, with, or after a meal?

Most places I have looked e.g NHS and Mayo Clinic state that, It's best to take metformin with a meal to reduce the side effects. The most common side effects are feeling and being sick, diarrhoea, ...
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What is the rationale of using Metformin in Pre-Diabetes and Type 2 Diabetes?

Mechanism of action of Metformin is Ultimately, it decreases gluconeogenesis (glucose production) in the liver Gluconeogenesis results from breaking up of fat. Metformin also inhibits cellular ...
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Covid-19 mortality rates lower among some diabetes patients

It has been found that hospitalized COVID-19 patients have a greater risk of dying if they are men or are obese or have complications from diabetes or hypertension (University of Maryland School of ...
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Does research show that Metformin alleviates/mitigates Adult Acne in PCOS women?

I'm an adult woman in her 30's, who suffers from Poly-Cystic-Ovarian-Syndrome (PCOS). My doctor has proscribed me Metformin to treat/manage my PCOS. Since PCOS can be one of the several causes for ...
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How does metformin interact with nicotine?

Does co-use of nicotine replacement therapy and metformin increase lactic acidosis risk? If so, how?
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55 views

Mechanism of Metformin in Lactic Acidosis

High dosages of metformin and other biguanides are liked to lactic acidosis. What is the pharmacological mechanism behind this? I am aware the people have survived doses as high as 63 grams, but at ...
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1answer
451 views

Bio identical cortisol and metformin

I am on bio identical hormone replacement including cortisol for low levels. Is it good to take metformin when taking cortisol for low cortisol levels? I thought I read somewhere that metformin lowers ...
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571 views

What does metformin do to treat polycystic ovarian syndrome?

Metformin is a drug used to treat diabetes but one of its off-label uses is to treat Polycystic Ovarian Syndrome. What does metformin do for someone who has PCOS but does not have diabetes? Is ...