Questions tagged [medications]
Questions related to intake, use, safety, side effects, pharmacokinetics, pharmacodynamics, drugs, prodrugs and medication.
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Eye drops came to mouth through eyes
I was using eye drops for allergy, after some time felt bitter taste in my mouth. I unknowingly consumed a little of it.
So generally is it OK to consume nasal, eye, ear drops that come in mouth ...
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How much T4 increase do you get per mcg of levothyroxine?
A normal starting dose of levothyroxine is 50 mcg per day. According to ATA, absorption is 60-80%. Let's assume 70% and let's assume 5 L of blood in the average human being.
50 mcg * 0.7 / 5.0 = 7 ...
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How does donepezil impact the immune system?
Is it immunosuppressive? If so, to what extent? What are the mechanisms for this effect?
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Will there never be a cure for cancer? [closed]
They've yet to come up with anything except pumping you with poisons that merely give you an extra year or two to live while you suffer humiliating side-effects.
When you ask experts about why they'...
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Can amphetamines suppress reactivity to scratch testing (for immunotherapy)?
My understanding's that amphetamines are immunosuppressive... Theoretically, couldn't these drugs result in false negatives?
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Immune system & methylphenidate?
How and to what extent does methylphenidate impact immune system function? How does its impact compare to that of amphetamines?
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How does metformin interact with nicotine?
Does co-use of nicotine replacement therapy and metformin increase lactic acidosis risk? If so, how?
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Elderly Father Takes Prevacid for last 20 years, seems to do more harm, how to stop [closed]
Note: Requesting guidance on how to approach, not medical advice.
My Dad is in his early 70s and has taken Prevacid once a day for nearly 20 years.
After eating food would come up after an hour. ...
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Synthroid : 30 minutes to 1 hour before meal. What if person waits more than 1 hour
My dad is currently taking Synthroid and according to instructions (link)
Use SYNTHROID only as ordered by your doctor. Take SYNTHROID as a single dose, preferably on an empty stomach, one-half to ...
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Fact or Hoax : Unconventional method of saving human life from stroke?
When someone gets a stroke their capillaries in the brainare gradually tearing. Usually, we bring the patient to the nearesthospital for immediate treatment.
On the other hand.
There's one ...
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What's The Minimum Staffing/Logistics For Running A Hospital?
Specifically, a hospital serving a local population of 200-400 people, and assuming departments include ER, ICU, dentistry, maternity, outpatient, pharmaceutical, radiology, and general surgery. What ...
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Is Depo-Provera shot directly start working?
Is Depo Provera shot directly start working or waiting must be required for it's effects. Secondly when the second shot should be conducted? Exactly after three months or can a delay of one to three ...
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What is the amount of caffeine in the human body over time?
Let's say I know how much caffeine I drank and when. Just knowing my sex, weight (and maybe height), what is the best estimate for how much caffeine is in my system now?
For example: Suppose I drank ...
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Why do some medications have HCl?
I have seen a lot of medications including a few that I take for certain situations. 1 of the medications that I occasionally take is Benadryl. The main component of this is Diphenhydramine HCl. I ...
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how does the immune system identify allergens? application: varenicline and lobeline
I'm wondering if we know how the immune system identifies allergens. My biochemistry knowledge is basic so I apologize if I use concepts incorrectly! Specifically, I want to know about the likelihood ...
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Why is Chlorprothixene not approved for use in the United States?
The medicament Chlorprothixene has been around since 1959. Why is it not approved for use in the United States?
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Do fiber pills interfere with prescrption medications?
Do fiber pills interfere with the absorption or efficacy of prescrption medications?
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At what daily dose does daily aspirin use become dangerous for a long-term user?
Many people take 80-300mg a day of aspirin for cardiovascular reasons; while, from what I've seen online, arthritis patients take up to 3000mg a day (is this correct?). But what are the increased ...
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To what extent does filling more prescriptions increase the number of medication errors?
https://www.usatoday.com/story/news/nation-now/2017/05/10/skin-melts-off-medication-error/315930001/ (mirror) says:
According to the Food and Drug Administration, medication errors jumped from 16,...
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Medicine/drug to "get along" with difficult people?
This is not a solicitation for medical advice. If I want a medical opinion I know I need to see a doctor.
Are there specific medicines, drugs and/or substances which:
are legal in the USA without a ...
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Are there any significant differences between Triceba and Toujeo?
I'm currently taking a long-acting insulin called Triceba. But I recently changed my health insurance, and the new insurance doesn't cover Triceba, it only covers another long-acting insulin called ...
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Why has the number of medication errors increased by 463% between 2010 and 2016 in the US?
https://www.usatoday.com/story/news/nation-now/2017/05/10/skin-melts-off-medication-error/315930001/ (mirror) says:
According to the Food and Drug Administration, medication errors jumped from 16,...
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Can medicines which expired a month ago be consumed safely?
I have few expensive nutritional supplements which expired in April (as in the label). Can I still consume it in May?
Of course, consuming expired medicines is not advised. However, can't they be ...
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What is a PAINs (pan-assay interference compounds)? How do you prove that a compound is a PAIN? And IMPs (invalid metabolic compund)?
I've been reading about curcumin and it seems to have been pretty useful in numerous clinical trials (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535097/), although its biodisponibility is "abysmal" ...
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GI bleeds in IV vs Oral steroids
Is there any evidence of the risk of GI bleeding when comparing IV vs Oral steroids e.g. hydrocortisone Vs Prednisone Vs dexamethasone. The only information I can find is the following picture from ...
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Is there a medical database with data (measured from patients) for research?
I am currently working on a mathematical project about optimisation problems in pharmacokinetics. To make it more practical and interesting, I was thinking of making some computations on actual data. ...
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What causes asymptomatic itching with rarely distributed rash?
Preface:
I am not a student of medicine or a medical professional by any means. All uses of anatomic and biologic terms come from a general education plus a little hobby-knowledge. Misuses of such ...
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Nootropics for epileptics
Hello guys!
I'm epileptic and last months I have some problems with my attention and my memory. Another problem is, I'm from Russia and we don't have here good pills or really qualified doctors and ...
user8936
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Is Arcalion 200mg by Servier good for ADHD [closed]
I'm curious why is it not wide spread and well-known I'm hesitant to begin a one month course. any suggestions ?
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can I take pills before food?
Some medicine is required to take with food. This question asked how much food you need to take.
But I'm interested if you can take pills and then eat later (20-30 min).
Is it considered that you ...
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What are ibuprofen alternatives without the side effects
Came across an article saying that Ibuprofen blocking COX-1 and COX-2 has side effects:
They work by inhibiting enzymes called cyclooxygenase 1 (COX-1) and 2
(COX-2). These are involved in a ...
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Should I take 9 year old Tylenol with codeine?
Recently I strained a muscle in my shoulder; the throbbing pain got so bad that I, uncharacteristically, took pills for the pain; namely some old Robaxal that I had sitting around from 6 or 7 years ...
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How does immunosuppressant affect immune system?
I'm talking Immuran (azathioprine) and I would like to know what it does to immune system exactly. I'm not a doctor but I'm asking here just to learn.
Does it kill all white cells? Does it reduce the ...
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Taking pills A + B individually instead of 1 cold medication that has A + B + C + D, bad idea?
When you have cold symptoms and go the pharmacy, you have two categories of choices:
Individual over-the-counter medications to treat specific symptoms, such as:
Pain reliever/fever reducer (example:...
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How do doctors decide on the duration of an antibiotic regimen?
Many upper respiratory infections, otitis media in children, sinusitis and other infections, are treated with antibiotics (if these are bacterial infections, of course). Doctors usually prescribe a ...
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Peripherally active sympatholytics?
Are there any sympatholytics or monoamine depleters that are purely peripherally active? I'm looking for something like prazosin or reserpine that doesn't cross the blood brain barrier.
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Can someone get addicted to codeine by taking a few tablets in a month?
I've been having a migraine for a long time, tried different medications, different doctors. recently (for a few months) i noticed that the only medicine that really works for me when i have an attack ...
user8161
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Turmeric vs Ibuprofen
Is there any truth in what is said here, that Ibuprofen is toxic to heart muscle and turmeric is an effective alternative? I have tried to find the study mentioned but cannot find it.
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How could Lyrica (pregabalin) cause hallucinations?
I've heard of this happening on rare occasion, but I cannot figure out a sensible mechanism.
I have some limited understanding of neurology and the function of GABA, and I know that ethanol (a GABA ...
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How can I bypass the most expensive drug in the world which goes on sale and get cured? [closed]
I have an ALS-like disease called SMA type III. It's a progressive neurodegenerative disease and there was no cure until recently. I have been waiting for a cure for forty years. Thanks to ...
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Quick way to determine if a medication is processed in the kidneys or liver?
What is a quick way to determine if a medication is processed in the kidneys or liver (or elsewhere)?
For example, let's take a few common medications: acetaminophen, aspirin, ibuprofen, and naproxen....
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Suffering from Gout problem need help? [closed]
I am 17 years old teenager, recently my joint at ankles got swollen, I thought its normal but next day I was unable to walk due pain in joint. So we wentt to Doctor using mine blood reports and in ...
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Is it possible to spread cough even if I'm not coughing?
I don't have a cough but sometimes when I go into a place a moment later a person starts to cough. Last time I met my friend that I didn't seen for a long time, having some conversation after a few ...
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Sublingual Spray Protocol
I want to start learning about sublingual spray mechanisms.
Where can I start with?
Thanks in advance
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What could be the reason for difference in adverse effects profile between original and generic Clopidogrel?
I was consulted on the following clinical case:
An elderly woman (over 65 years old) on Plavix due to 2 CVAs in the last few years. Six months ago treatment was changed to a generic Clopidogrel ...
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Long term effects of an allergy pill? Loratadine
Are there any studies/effects of long term use of an allergy pill? I use Loratadine to help control my environmental allergies but I'm concerned about it being an every-day thing. Am I facing any ...
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What is the mechanism by which paracetamol improves sleep?
45+ old male sleep maintenance issues for couple of years resolved by fixing the basics- blacked out room, avoiding alcohol and coffee having the biggest effect. Still even if I am able to sleep 8 ...
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How do extended release tablets work?
I know these tablets are especially formulated and coated to dissolve over a certain period of time. I also notice that all I've seen, quite a lot, are too large to pass through the Pylorus. Do they ...
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Mechanism of Metformin in Lactic Acidosis
High dosages of metformin and other biguanides are liked to lactic acidosis. What is the pharmacological mechanism behind this?
I am aware the people have survived doses as high as 63 grams, but at ...
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Do proton pump inhibitors (PPIs) shut down all the proton pumps in all cells across our body?
It's known that proton pumps exist in all cells in our bodies and help us to get rid of damaged proteins (present a disposal system).
PPIs (omeprazole, pantoprazole, esomeprazole, lansoprazole and ...
user3462