Questions tagged [medications]

Questions related to intake, use, safety, side effects, pharmacokinetics, pharmacodynamics, drugs, prodrugs and medication.

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Citrate vs EDTA

What is the difference between the use of «citrate» and «EDTA» as an anticoagulant in medicine (I know that each one is used for some dosages but not the other, but I need to know why)?
user16752's user avatar
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2 votes
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68 views

What is the expected life span of vascular stents?

What is the expected life span of vascular stents? For example: Universal (coronary/venous) stent WALLSTENT-UNI Boston Scientific, metal: nitinol = titanium + nickel. How many pulsating contractions ...
Alex's user avatar
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Cancer treatment through regulation of myeloid-derived suppressor cells

There are many ongoing clinical trials that leverage the power of the immune system to recognize tumor cells such as CD47 and PDL1/PD1, and even engineered T cells! I ran across an immune cell type ...
James Hong's user avatar
2 votes
0 answers
75 views

Can blood flow destroy part of the metal stent in 10 to 40 years?

If a part of the metal stent has not grown into a vessel, can this part of the stent be washed out by the blood flow in 10 to 40 years (theoretically)? Also are such cases known that blood flow ...
Alex's user avatar
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2 votes
2 answers
305 views

Why is it that psychoactive drugs tend to be dangerous?

I'm personally not a big fan of recreational drugs, illicit or otherwise, but there's an interesting medical question buried in their use. Why is it that substances that make you feel good tend to be ...
TheEnvironmentalist's user avatar
5 votes
1 answer
77 views

How are the administration times for medications determined?

Many prescribed medications give a rate at which to apply the medication, and "over-the-counter" medications often have a minimum time period between dosages the users of the medications are not to go ...
Ryan1729's user avatar
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7 votes
1 answer
338 views

Why isn't paracetamol routinely combined with n-acetylcysteine?

Whether it's acute large dose paracetamol or long term regular dosage of paracetamol usage, it is a problem for the liver, ototoxic and even potentially life-threatening. While one might question the ...
LаngLаngС's user avatar
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4 votes
1 answer
69 views

Is it dangerous to administer valproic acid to an adult with an autism spectrum disorder?

I read that the administration of valproic acid to pregnant mothers can cause fetal developmental problems, such as autism spectrum disorder (ASD) (Miyazaki et al, 2005). Can its administration to an ...
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2 votes
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110 views

Please explain the algebraic reasoning in this textbook

I am reading Dennis M. Brown “Drug Delivery Systems in Cancer”. On Page 29 when referring to monotonic increase or decrease of n (being the number of cells n(t) I believe) then how are they getting ...
Brian Wiley's user avatar
6 votes
2 answers
245 views

Are there beneficial compounds in cigarette smoke?

The UKPDS 50 study suggested that smokers experience lower rates of diabetic retinopathy Somewhat counter-intuitively, smoking status was inversely related to the development of new lesions and to ...
Jay K's user avatar
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6 votes
1 answer
102 views

Barrett's esophagus (BO) and proton-pump inhibitors (PPIs)

I have come across an interview with a European gastroenterologist (apparently from 2006) where he argues that in cases where a reflux disease does not cause typical symptoms even the presence of a ...
Drux's user avatar
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1 answer
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How (un)suitable are veterinary products for human health?

We've all seen movies in which gangsters are treated by (paid or coerced) veterinarians in order to avoid law enforcement in hospitals. How bad are animal-grade pharmaceuticals for human health, in ...
Mowgli's user avatar
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1 vote
1 answer
48 views

Longterm effects on DNA of aciclovir

Since aciclovir works by decreasing the production of the virus's DNA, one might fear that it also damages DNA of healthy cells. I know that it is usually said that aciclovir doesn't affect healthy ...
alex's user avatar
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4 votes
2 answers
174 views

Why does acne get worse during the first two weeks of treatment with isotretinoin?

I've heard and read from multiple sources that acne gets worse during the first two weeks of treatment with isotretinoin, but I haven't been able to find an explanation as to why this happens. From ...
Ivo3185's user avatar
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1 vote
0 answers
111 views

Prozac, Ritalin and Valium..together [closed]

There is a certain movie in which one the characters takes Prozac, Ritalin and Valium..together. When someone asks him what it is, he states the composition, adding "Breakfast of Champions". Being ...
George Menoutis's user avatar
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1 answer
1k views

Why is hydrocortisone mixed with clotrimazole in anti-fungal medication?

Considering clotrimazole is the active ingredient killing the fungus.
NoName's user avatar
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3 votes
1 answer
439 views

What does JP mean after a medicine/compund name?

I take Methycobalamin (Vitamin B12) supplements. I noticed the tablet packaging reads "Each Sugar coated tablet contains Mecobalamin JP 500 mcg" What does JP mean here? Thank you.
Ram Keswani's user avatar
2 votes
1 answer
97 views

Do all Eye drops for dry eyes contain steriods?

Do all eye drops for the dry eyes contain steroid? How can you check if the eye drops include steroids in it?
jen138581's user avatar
3 votes
0 answers
54 views

How much does what you eat impact medication absorption? [closed]

Some medications advise being taken with food, generally either to prevent stomach irritation as is the case with NSAIDs, or to improve absorption, as is the case with numerous other medications. How ...
TheEnvironmentalist's user avatar
1 vote
0 answers
28 views

Why do most drugs target G-protein receptors?

I've read that more than 50% drugs target the g-protein coupled receptors: What is so special with them that they are the targets for such a wide range of diseases?
Mitali Kapoor's user avatar
3 votes
0 answers
80 views

Must one take anticoagulants lifelong after stenting of deep veins with a non-thrombotic lesion?

Must one take anticoagulants lifelong after stenting of deep veins with a non-thrombotic lesion, for example, aorto-venous conflict (May-Thurner syndrome)? Or is it enough to take anticoagulants only ...
Alex's user avatar
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4 votes
1 answer
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Is cannabidiol safe to treat depression of a patient with a schizoaffective disorder?

According to wikipedia CBD might be useful as an antidepresant: "CBD has been shown to act as a serotonin 5-HT1A receptor partial agonist,[33] and this action may be involved in its ...
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1 vote
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34 views

Can marigold extract be used in mosquito repellent ointment?

I am doing research on mosquito repellent as a part of my college project. I have found various sources of marigold being used as insect repellent such as the following link- https://www.ncbi.nlm....
Ritu Karna's user avatar
5 votes
2 answers
1k views

Why does Melarsoprol have to be injected in glass syringes?

A WHO document, contains the statement [Melarsoprol] injections must be performed using glass syringes. Why is this the case?
Barry Harrison's user avatar
2 votes
2 answers
36 views

Term for manufactured drug

What is the English term for a manufactured pharmaceutical drug of a specific strength and dosage form, i.e. a pill, an ointment etcetera?
August Karlstrom's user avatar
2 votes
0 answers
25 views

Meaning of "potential pharmacogenetic characterisation might also be evaluated so that these syndromes are treated at an earlier age."

This could be offtopic because this might be just a case of sloppy phrasing and a case of "asking to guess what the authors really meant". A quote from an abstract (GTP-cyclohydrolase deficiency ...
CowperKettle's user avatar
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3 votes
1 answer
250 views

Why do doxycycline pills also contain lactose?

Prescriptions in the UK contain doxycycline as doxycycline hyclate. They are also listed as containing lactose. Why is the lactose helpful?
Tomi's user avatar
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4 votes
1 answer
251 views

Migraines and tryptophan

One theory about migraines is that it is triggered by dropping serotonin levels. One medication, sumatriptan, acts by raising serotonin acting as a reuptake inhibitor. Since tryptophan is converted ...
user's user avatar
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6 votes
1 answer
148 views

Why is episodic use of infliximab associated with a higher incidence of antibody formation towards the drug?

It has been shown in many studies that episodic use of infliximab (and other Anti-TNF agents) increases the incidence of antibody formation towards the drug, when compared with giving the drug on a ...
F Chopin's user avatar
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1 vote
1 answer
1k views

Dextroamphetamine vs Dextroamphetamine Salt Combo

Important: I've already consulted my doctor and am not seeking medical advice. I'm just curious here. I've been prescribed and have taken Dextroamphetamine for some time (round orange pill). Recently ...
LearnWorkLearn's user avatar
3 votes
1 answer
179 views

Is the drug's effectiveness directly proportional to the half life formula?

For instance half life of a 150ml drug injected to you is 50 days (so you have 75ml left in your system). At 100 days you'll have 37.5ml left in your system. But does that mean the drug is most ...
Pherdindy's user avatar
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1 vote
1 answer
588 views

Inhaling pills possible?

A friend of mine told me some time ago that it actually can be dangerous to take pills (the process of taking it), which to me seemed like a pretty bold statement -- swallowing a pill doesn't seem to ...
Markus Kahn's user avatar
1 vote
1 answer
176 views

At what point would blood loss impede the ability to achieve an erection?

So first I feel I should clarify this isn't to support some vampire fetish. No this is actually to bring some scientific fact to my fictional work. How many pints in a one month period could an ...
anon's user avatar
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2 votes
3 answers
161 views

What to do if someone mistakenly ingests food contraindicated by medication requirements?

In the past I have read a couple of times that one should not consume milk-based-products when taking certain medication for a certain amount of time before and after taking the product. To be a ...
Manuel Schubert's user avatar
1 vote
0 answers
41 views

Where can I find the original brand names of every psychotropic medication?

I'm looking for a place to find the original (initial) brand name of every psychotropic medication when it was first introduced (internationally, not necessarily in the US). I'm not interested in ...
Adrian Popa's user avatar
0 votes
1 answer
88 views

How does total mg of medicines effect human body?

Most of people are concious about taking medicines by seeing the mg level of medicines as they think that high mg of medicine can effect their body so they limit the use of medicine of high mg instead ...
ME.'s user avatar
  • 11
1 vote
2 answers
132 views

Is ShockWave Therapy Useful For ED or not?

I read the following in an article from a Facebook page for a clinic in the Lebanon region, and I am trying to know if this choice is good or not?: Extracorporeal ShockWave Therapy, or ESWT, is a ...
Mohamad Mahmoud Darwish's user avatar
1 vote
0 answers
38 views

How does the med, Spironolactone, help with PCOS?

I've been taking Spironolactone for my acne for many years (I'm a woman in my late 20's now). I have been taking it for this intended purpose. The other day, a doctor was looking over my meds and for ...
Pills N Pillows's user avatar
1 vote
0 answers
42 views

What are the dangers of missing a dose and overdose? [closed]

I'm a computer engineering student that would like to address this issue on my next project using prototype and maybe a web-based software or app. But before that, I had to understand why patients ...
jtyg's user avatar
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6 votes
1 answer
411 views

Where does Ibuprofen inhibit COX-1, and what is its MoA?

Both ASA and Ibuprofen are COX-1 inhibitors. However, ASA inhibits the formation of the enzyme Thromboxan A2 through inhibition of COX-1 at SER 529, which is responsible for thrombocytes. That in turn ...
Narusan's user avatar
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4 votes
0 answers
32 views

NHS free prescriptions [closed]

If the UK National Health Service offers free prescriptions to certain groups of society, How is the medicine payed for ? My question is do the various drug companies have a 'deal' with the NHS to ...
andersj's user avatar
  • 49
0 votes
1 answer
118 views

Can scopolamine really be given through the ear?

As you might have seen theres a new facebook post going around about a 22 year old women who was drugged in a mall. Supposedly a group of men had 'blown a substance in her ear' and she nearly passed ...
Summer's user avatar
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2 votes
0 answers
79 views

hair repigmentation and growth from secukinumab

I saw this study(link) about a patient who received a drug called secukinumab and experienced hair re-pigmentation from white to black and hair re-growth and as you can see the results are pretty ...
petrichor's user avatar
-1 votes
1 answer
103 views

a cure for gray hair is on the way? [closed]

I saw this news article (here is the article about it in a medical journal) and began to wonder if the cure for gray hair is on the way. Those immunotherapy drugs can restore hair color only in people ...
petrichor's user avatar
5 votes
4 answers
191 views

What methods are there for individuals to help them remember if they have taken their medicine?

Forgetfulness whether one has taken the medication already or not is not an uncommon problem. However, especially while taking different medication simultaneously, adherence to the prescription is ...
Martin's user avatar
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0 votes
1 answer
432 views

Can Cheek bone grow bigger and wider in adulthood when you gain weight? [duplicate]

From somewhere, I might have been heard that If you gain weight even in your adulthood when your growth has been finished, Facial bones can grow because obesity causes hormone balance problems(such as ...
user13622's user avatar
1 vote
1 answer
84 views

Why is Tradozone prescribed to aid with insomnia?

Per Wikipedia article: Many clinicians use low-dose trazodone as an alternative to benzodiazepines for the treatment of insomnia. Two recent reviews found that trazodone is the second most ...
Tomáš Zato's user avatar
1 vote
0 answers
54 views

Is benzoyl peroxide as body wash less effective than creams? [closed]

For severe acne, wouldn't it be most effective to contact and subject the affected areas to Benzoyl Peroxide (BPO) for as long as possible? If yes, then ought it not be applied as a cream? As a body ...
user avatar
4 votes
0 answers
204 views

Why are certain drugs prescribed more often to either males or females?

I have some original data on prescription frequencies of certain common drugs and I have calculated the gender ratio of patients for each. The list below contains Top 15 of the most commonly ...
Mihail's user avatar
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6 votes
2 answers
217 views

Does Dextromethorphan actually suppress coughing?

I had a pretty annoying dry cough a while ago following a cold. In the list of incredients for a cough syrup that I used, it said: Each 5 mL or 1 teaspoonful (tsp.) contains: DM | Cough Suppressant: ...
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