Questions tagged [medications]
Questions related to intake, use, safety, side effects, pharmacokinetics, pharmacodynamics, drugs, prodrugs and medication.
412
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Citrate vs EDTA
What is the difference between the use of «citrate» and «EDTA» as an anticoagulant in medicine (I know that each one is used for some dosages but not the other, but I need to know why)?
2
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What is the expected life span of vascular stents?
What is the expected life span of vascular stents?
For example: Universal (coronary/venous) stent WALLSTENT-UNI Boston Scientific, metal: nitinol = titanium + nickel.
How many pulsating contractions ...
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0
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28
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Cancer treatment through regulation of myeloid-derived suppressor cells
There are many ongoing clinical trials that leverage the power of the immune system to recognize tumor cells such as CD47 and PDL1/PD1, and even engineered T cells!
I ran across an immune cell type ...
2
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0
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Can blood flow destroy part of the metal stent in 10 to 40 years?
If a part of the metal stent has not grown into a vessel, can this part of the stent be washed out by the blood flow in 10 to 40 years (theoretically)?
Also are such cases known that blood flow ...
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2
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Why is it that psychoactive drugs tend to be dangerous?
I'm personally not a big fan of recreational drugs, illicit or otherwise, but there's an interesting medical question buried in their use.
Why is it that substances that make you feel good tend to be ...
5
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1
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How are the administration times for medications determined?
Many prescribed medications give a rate at which to apply the medication, and "over-the-counter" medications often have a minimum time period between dosages the users of the medications are not to go ...
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338
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Why isn't paracetamol routinely combined with n-acetylcysteine?
Whether it's acute large dose paracetamol or long term regular dosage of paracetamol usage, it is a problem for the liver, ototoxic and even potentially life-threatening.
While one might question the ...
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Is it dangerous to administer valproic acid to an adult with an autism spectrum disorder?
I read that the administration of valproic acid to pregnant mothers can cause fetal developmental problems, such as autism spectrum disorder (ASD) (Miyazaki et al, 2005).
Can its administration to an ...
2
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1
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Please explain the algebraic reasoning in this textbook
I am reading Dennis M. Brown “Drug Delivery Systems in Cancer”. On Page 29 when referring to monotonic increase or decrease of n (being the number of cells n(t) I believe) then how are they getting
...
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2
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245
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Are there beneficial compounds in cigarette smoke?
The UKPDS 50 study suggested that smokers experience lower rates of diabetic retinopathy
Somewhat counter-intuitively, smoking status was inversely related to the development of new lesions and to ...
6
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Barrett's esophagus (BO) and proton-pump inhibitors (PPIs)
I have come across an interview with a European gastroenterologist (apparently from 2006) where he argues that in cases where a reflux disease does not cause typical symptoms even the presence of a ...
2
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How (un)suitable are veterinary products for human health?
We've all seen movies in which gangsters are treated by (paid or coerced) veterinarians in order to avoid law enforcement in hospitals. How bad are animal-grade pharmaceuticals for human health, in ...
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Longterm effects on DNA of aciclovir
Since aciclovir works by decreasing the production of the virus's DNA, one might fear that it also damages DNA of healthy cells. I know that it is usually said that aciclovir doesn't affect healthy ...
4
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2
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Why does acne get worse during the first two weeks of treatment with isotretinoin?
I've heard and read from multiple sources that acne gets worse during the first two weeks of treatment with isotretinoin, but I haven't been able to find an explanation as to why this happens.
From ...
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Prozac, Ritalin and Valium..together [closed]
There is a certain movie in which one the characters takes Prozac, Ritalin and Valium..together. When someone asks him what it is, he states the composition, adding "Breakfast of Champions".
Being ...
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Why is hydrocortisone mixed with clotrimazole in anti-fungal medication?
Considering clotrimazole is the active ingredient killing the fungus.
3
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What does JP mean after a medicine/compund name?
I take Methycobalamin (Vitamin B12) supplements.
I noticed the tablet packaging reads "Each Sugar coated tablet contains Mecobalamin JP 500 mcg"
What does JP mean here?
Thank you.
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answer
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Do all Eye drops for dry eyes contain steriods?
Do all eye drops for the dry eyes contain steroid?
How can you check if the eye drops include steroids in it?
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How much does what you eat impact medication absorption? [closed]
Some medications advise being taken with food, generally either to prevent stomach irritation as is the case with NSAIDs, or to improve absorption, as is the case with numerous other medications.
How ...
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Why do most drugs target G-protein receptors?
I've read that more than 50% drugs target the g-protein coupled receptors: What is so special with them that they are the targets for such a wide range of diseases?
3
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Must one take anticoagulants lifelong after stenting of deep veins with a non-thrombotic lesion?
Must one take anticoagulants lifelong after stenting of deep veins with a non-thrombotic lesion, for example, aorto-venous conflict (May-Thurner syndrome)?
Or is it enough to take anticoagulants only ...
4
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Is cannabidiol safe to treat depression of a patient with a schizoaffective disorder?
According to wikipedia CBD might be useful as an antidepresant:
"CBD has been shown to act as a serotonin 5-HT1A receptor partial
agonist,[33] and this action may be involved in its
...
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Can marigold extract be used in mosquito repellent ointment?
I am doing research on mosquito repellent as a part of my college project. I have found various sources of marigold being used as insect repellent such as the following link-
https://www.ncbi.nlm....
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2
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Why does Melarsoprol have to be injected in glass syringes?
A WHO document, contains the statement
[Melarsoprol] injections must be performed using glass syringes.
Why is this the case?
2
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2
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Term for manufactured drug
What is the English term for a manufactured pharmaceutical drug of a specific strength and dosage form, i.e. a pill, an ointment etcetera?
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Meaning of "potential pharmacogenetic characterisation might also be evaluated so that these syndromes are treated at an earlier age."
This could be offtopic because this might be just a case of sloppy phrasing and a case of "asking to guess what the authors really meant". A quote from an abstract (GTP-cyclohydrolase deficiency ...
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Why do doxycycline pills also contain lactose?
Prescriptions in the UK contain doxycycline as doxycycline hyclate. They are also listed as containing lactose.
Why is the lactose helpful?
4
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1
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Migraines and tryptophan
One theory about migraines is that it is triggered by dropping serotonin levels.
One medication, sumatriptan, acts by raising serotonin acting as a reuptake inhibitor.
Since tryptophan is converted ...
6
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1
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Why is episodic use of infliximab associated with a higher incidence of antibody formation towards the drug?
It has been shown in many studies that episodic use of infliximab (and other Anti-TNF agents) increases the incidence of antibody formation towards the drug, when compared with giving the drug on a ...
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Dextroamphetamine vs Dextroamphetamine Salt Combo
Important: I've already consulted my doctor and am not seeking medical advice. I'm just curious here.
I've been prescribed and have taken Dextroamphetamine for some time (round orange pill). Recently ...
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Is the drug's effectiveness directly proportional to the half life formula?
For instance half life of a 150ml drug injected to you is 50 days (so you have 75ml left in your system). At 100 days you'll have 37.5ml left in your system. But does that mean the drug is most ...
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588
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Inhaling pills possible?
A friend of mine told me some time ago that it actually can be dangerous to take pills (the process of taking it), which to me seemed like a pretty bold statement -- swallowing a pill doesn't seem to ...
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At what point would blood loss impede the ability to achieve an erection?
So first I feel I should clarify this isn't to support some vampire fetish. No this is actually to bring some scientific fact to my fictional work.
How many pints in a one month period could an ...
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3
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What to do if someone mistakenly ingests food contraindicated by medication requirements?
In the past I have read a couple of times that one should not consume milk-based-products when taking certain medication for a certain amount of time before and after taking the product. To be a ...
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Where can I find the original brand names of every psychotropic medication?
I'm looking for a place to find the original (initial) brand name of every psychotropic medication when it was first introduced (internationally, not necessarily in the US).
I'm not interested in ...
0
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1
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How does total mg of medicines effect human body?
Most of people are concious about taking medicines by seeing the mg level of medicines as they think that high mg of medicine can effect their body so they limit the use of medicine of high mg instead ...
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2
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Is ShockWave Therapy Useful For ED or not?
I read the following in an article from a Facebook page for a clinic in the Lebanon region, and I am trying to know if this choice is good or not?:
Extracorporeal ShockWave Therapy, or ESWT, is a ...
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0
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How does the med, Spironolactone, help with PCOS?
I've been taking Spironolactone for my acne for many years (I'm a woman in my late 20's now). I have been taking it for this intended purpose. The other day, a doctor was looking over my meds and for ...
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What are the dangers of missing a dose and overdose? [closed]
I'm a computer engineering student that would like to address this issue on my next project using prototype and maybe a web-based software or app.
But before that, I had to understand why patients ...
6
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1
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Where does Ibuprofen inhibit COX-1, and what is its MoA?
Both ASA and Ibuprofen are COX-1 inhibitors. However, ASA inhibits the formation of the enzyme Thromboxan A2 through inhibition of COX-1 at SER 529, which is responsible for thrombocytes. That in turn ...
4
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NHS free prescriptions [closed]
If the UK National Health Service offers free prescriptions to certain groups of society, How is the medicine payed for ?
My question is do the various drug companies have a 'deal' with the NHS to ...
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1
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118
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Can scopolamine really be given through the ear?
As you might have seen theres a new facebook post going around about a 22 year old women who was drugged in a mall. Supposedly a group of men had 'blown a substance in her ear' and she nearly passed ...
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0
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hair repigmentation and growth from secukinumab
I saw this study(link) about a patient who received a drug called secukinumab and experienced hair re-pigmentation from white to black and hair re-growth and as you can see the results are pretty ...
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a cure for gray hair is on the way? [closed]
I saw this news article (here is the article about it in a medical journal) and began to wonder if the cure for gray hair is on the way. Those immunotherapy drugs can restore hair color only in people ...
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4
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What methods are there for individuals to help them remember if they have taken their medicine?
Forgetfulness whether one has taken the medication already or not is not an uncommon problem. However, especially while taking different medication simultaneously, adherence to the prescription is ...
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1
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Can Cheek bone grow bigger and wider in adulthood when you gain weight? [duplicate]
From somewhere, I might have been heard that If you gain weight even in your adulthood when your growth has been finished, Facial bones can grow because obesity causes hormone balance problems(such as ...
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1
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Why is Tradozone prescribed to aid with insomnia?
Per Wikipedia article:
Many clinicians use low-dose trazodone as an alternative to benzodiazepines for the treatment of insomnia. Two recent reviews found that trazodone is the second most ...
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0
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Is benzoyl peroxide as body wash less effective than creams? [closed]
For severe acne, wouldn't it be most effective to contact and subject the affected areas to Benzoyl Peroxide (BPO) for as long as possible? If yes, then ought it not be applied as a cream?
As a body ...
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Why are certain drugs prescribed more often to either males or females?
I have some original data on prescription frequencies of certain common drugs and I have calculated the gender ratio of patients for each. The list below contains Top 15 of the most commonly ...
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Does Dextromethorphan actually suppress coughing?
I had a pretty annoying dry cough a while ago following a cold. In the list of incredients for a cough syrup that I used, it said:
Each 5 mL or 1 teaspoonful (tsp.) contains:
DM | Cough Suppressant: ...