Questions tagged [medications]
Questions related to intake, use, safety, side effects, pharmacokinetics, pharmacodynamics, drugs, prodrugs and medication.
410
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Is metamizole associated with rebound headaches?
I can't find any specific mention on the internet if Metamizole (most known as dipyrone) is specifically associated with rebound headaches like other pain relieve medications like Aspirin, ...
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If placebo controls work even when the patient is aware that the treatment is a placebo. Why are deceptive placebo controls used?
Placebos are “fake” treatments prescribed for the psychological benefit to the patient rather than for any physiological effect. Placebos are used for conditions defined by “self-observation” symptoms ...
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Tick bite treatment. Doxycycline intake suspended after 3 days only. If substituted by Bactrim, is there a risk to develop bacteria resistant?
A patient was bitten by a tick and carried the tick on his skin for 5/6 days (which got engorged at the end).
Then the tick dropped spontaneously.
He has been prescribed a preventive antibiotic course ...
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Why are some medicines recommended to be taken with a high dose and low frequency?
Alendronate sodium is an osteoporosis medicine commonly recommended
as a once-a-week 70 mg dose.
Why not 35 mg twice a week? or 10 mg daily? I am guessing that a more
steady intake like this would be ...
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Book of drug interactions
Where can I find full list of drug _ drug interaction & adverse reaction, apart from pdr.net, I mean to say in a book form. What books of medical science contain these information? Please name a ...
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interaction between Mirtazapine & Mesalamine & olanzapine [closed]
Is there any adverse reaction or interaction between Mirtazapine & Mesalamine & olanzapine, If taken in low doses(mirtazapine 7.5 & Olanzapine 2.5).
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Why is methadone not prescribed with naloxone for opioid use disorder?
Two possible treatments for opioid use disorder are methadone or buprenorphine/naloxone (suboxone).
According to the National Alliance of Mental Illness(https://www.nami.org/About-Mental-Illness/...
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Where can I find a list (even if only partial) of excipients that cause a medication to be indivisible?
Certain tablet formulations should not be divided or halved because the tablets are film-coated for low pH resistance (i.e. for safe passage in the stomach) or because the active ingredient is not ...
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Are antibiotics the only class of drugs whose effectiveness reduces over time?
The phenomenon of antibiotic resistance is well known: an antibiotic is effective when first introduced to the market, but over the years, its effectiveness decreases as resistant strains of bacteria ...
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Why do corticosteroids have few kidney-related side effects?
Prostaglandins are involved with promoting various renal functions. Therefore, NSAIDs, like indomethacin which inhibits protaglandin formation through COX enzyme inhibition, tend to have many side-...
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Why is prothrombin time used to monitor warfarin and not aPTT?
Warfarin is said to change prothrombin time (PT) but not activated partial thromboplastin time (aPTT) (for practical purposes at least anyways, not really sure). But looking at the mechanism of action ...
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Is it useless to drip Vitamin D drops on your tongue? [closed]
One celebrity doctor in my country says that Vitamin D can be absorbed only in the small intestine and that dropping Vitamin D drops on your tongue is therefore useless, because most of the liquid ...
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Have any conclusions been made regarding the interaction of Covid-19 and ACE inhibitor medications? [duplicate]
About two months ago, I started to see articles appear regarding the potential interactions between ACE inhibitor medications (commonly used to treat high blood pressure) and the severity of Covid-19
...
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What exactly is the meaning of "No doping" sign on a drug package?
I noticed a "No doping" sign on the back of a pack of Dopamine HCl ampoules. It looks like this:
I was wondering what is the purpose of this sign. I am guessing that it means that the drug should not ...
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Prevent-Release Systems for Opioid Painkillers Vs Placebo
today we were studying oral novel drug delivery systems. The class was prerecorded (due to pandemic) There was this table in the slides "strategies and benefits of modifying drug release table" and I ...
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Does Ivermectin treat COVID-19 coronavirus infection?
Does the anti-parasitic Ivermectin work in actual human studies versus the Petri dish in vitro studies, when treating coronavirus COVID-19 infection? And if so, is it safe in humans?
An in vitro ...
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How is Lopinavir + Ritonavir expected to stop COVID-19?
There are four drugs being tested for effectiveness against COVID-19 in the SOLIDARITY trial. Three of them have obvious potential mechanisms of action:
Remdesivir is an RNA polymerase inhibitor. ...
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Why are multiple courses of isotretinoin necessary to treat acne?
The following guidances don't detail why multiple courses are more efficacious?
Aug 21 2019 PRODUCT MONOGRAPH on Accutane, Hoffmann-La Roche Limited, p. 13 of 36.
Effects of multiple courses of ...
user14
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What are the special medications to treat Covid-19?
We know there is no cure for Covid-19 (currently) and the
treatment focuses on managing symptoms as the virus runs its course.
The main symptoms of Covid-19 are
-Fever
-Cough
-Shortness of breath
...
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ACE2 Inhibition as therapeutic candidate?
Disclaimer: I am a scientist, but this is not my main field so sorry if I've not used the correct terminology at this busy time...
Since the coronavirus protein bonds with and gains entry to the cell ...
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Are there any central trackers for COVID-19 trials?
There are several aggregate central trackers for the spread of COVID-19. Like this one, for example.
Is there anything similar for trials? Or trials in the pipeline? Either vaccines or treatments?
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Can oseltamivir shorten the duration of COVID-19 and inhibit replication and transmission of the SARS-CoV-2 (2019-nCoV) virus?
Oseltamivir (Tamiflu) is an antiviral medication used to treat and prevent influenza A and influenza B (flu). It is said to reduce symptom duration even when initiated more than 2 days after symptom ...
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How do huge computer simulations help in medical research?
I found the there is a project Folding@home to fight against COVID-19. As far as I understand, it uses huge amount of computing power to find a cure. Why do we need such a huge number of potential ...
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88
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Tilt table test and beta blockers
Is tilt table test indicative with beta blockers for dysautonomia diagnosis? Or is it require drug withdrawal?
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Side-effects or other medical conditions for diabetic patients
I have a database of diabetic patients and their medication/lab test data as well.
1) I am planning to run a simple analysis like finding out incidence rate
example: amongst the T2DM patients that I ...
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T2DM medication treatment pathway
I am looking at the T2DM medications specified here and have a few questions about them.
1) Why don't I see drugs like Troglitazone, Tolazamide, Acarbose, Acetohexamide, Chlorpropramide, Miglitol? ...
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Rationale for Pilocarpine instillation after retrobulbar haemorrhage
BACKGROUND: Retrobulbar haemorrhage may occur due to retrobulbar block. Immediate pressure bandage after instilling one drop of 2% pilocarpine and postpone of operation for a week is advised.
What is ...
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T2DM diagnosis vs disorder due to T2DM diagnosis?
I have a database of diabetic patients. Mostly 80 % are T2DM patients. Now I would like to identify the T2DM patients based on their conditions reported. I mean when patients visit hospital (diabetic ...
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How to interpret diabetic complications?
I have a database of diabetic patients. Mostly 80 % are T2DM patients. Now I would like to identify the T2DM patients based on their conditions reported. I mean when patients visit hospital (diabetic ...
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Is there a greater benefit as as to why an ob-gyn will prescribe a birth control with higher risk of Venous Thromboembolism?
It is already known that combined oral contraceptive (COCs) pills increase the risk of serious complications such as Venous Thromboembolism. However there are other options that have relatively much ...
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General purpose vomit response control?
Is there a general purpose antiemetic for vomit response control?
Many vomit control solutions are focused on specific causes for the vomiting. Some common causes of nausea/vomiting:
Cancer ...
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What is the process of calculating if a molecule is helpful and/or harmful to an organism?
From reading about pharmacology through the years I synthesized from my own prior research that What is the process of calculating if a molecule is helpful and/or harmful to an organism is this:
A ...
user8225
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How does Diabetic specialist clinic work?
I am from IT domain and would like to seek some help on certain medicine related questions
I would like to know how does Diabetic specialist hospital/clinic work for Diabetic patients when compared ...
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What is daily sedation interruption for ventilated patients?
I was reading about ventilator bundle here and came across this term called Daily Sedation Interruption.
Does this term mean break in giving the sedation drugs?
How can this help in reducing the ...
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T2DM Fasting glucose level - extreme cases
I am working on clinical data analysis and currently dealing with T2DM patients.
When I look at their Fasting glucose level readings, I see that their values range from 0.9 mmol\L to 64 mmol\L
The ...
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Do patients with VAE stay in ICU for longer time?
I was reading online that people when put in ICU under mechanical ventilation, can develop Ventilated Associated Events.
What I would like to know is: does the stay in ICU increase for people who ...
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Fluid balance range for human
I am working on clinical data analysis with patients from icu who are mechanically ventilated and in ICU for 4 or more days.
Currently I tried to calculate their fluid balance based on the input and ...
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Why is Toradol no longer available in the US?
A few years ago I was given Toradol for kidney stone pain. It was magical. My friend just had a kidney stone and was given morphine, then Dilaudid. Curious about the differences, I went googling, only ...
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Drug dosage in pharmacology [closed]
Please give a overview about how the dosage of a particular drug (e.g. ciprofloxacin) is determined in pharmacology?
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Why did it take so long to notice that Zantac had carcinogenic ingredients?
Why did it take so long to notice that Zantac had carcinogenic ingredients?
Sanofi is recalling the popular heartburn drug Zantac.
The generic name for the drug is Ranitidine.
Apparently, the ...
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Why many usually-very-painful medical processes aren't done under conscious, generally painless-painkilling?
Many usually-very-painful medical or medical-defined processes such as:
Hair transplant
Lip botox
Fecal impaction removal
Dental cleaning (stone removal)
Aren't being done under conscious, generally ...
user8225
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Why/how are some drugs nephrotoxic?
I want to know the (more or less) exact mechanism by which specific nephrotoxic medications damage the kidneys. For some drugs it seems relatively intuitive that they interfere with the function of ...
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Is there an interaction between methamphetamine and dental anesthetic?
According to the sign shown in this post on Reddit, using methamphetamine and dental anesthetic together is lethal.
If you use Methamphetamines (Crystal Meth, Crank, Speed, Glass, Tweak, Yaba)...
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Ergotamine v Sumatriptan for migraine without aura
A randomized, double-blind comparison of sumatriptan and Cafergot in the acute treatment of migraine. The Multinational Oral Sumatriptan and Caferg... - PubMed - NCBI
It is concluded that oral ...
user14
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Why was Ergotamine (trade name: Cafergot) discontinued in Canada and UK?
My mom in HK was prescribed Ergotamine, but I'm unnerved discontinuation in Canada and UK! Something wrong with it?
Asked
13 Oct 2012 by lucyglitters
i live in the uk and i've been taking it for ...
user14
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what is the advantages (for patients) in delayed and extended release drugs?
What are the advantages for patients between extended and delayed release drugs?
i understand the difference between these two drugs, but i want to know the advantages to the patients itself between ...
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Lucidity and pain reduction link [closed]
I am a layman, so this is no doubt an overly broad and probably dumb question, but if someone will humor me and attempt to answer, I would greatly appreciate it. Why is it that studies tend to show a ...
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Is Racemic Epinephrine Compatible as Treatment For Anaphylaxis?
I am writing a work of fiction and want it as scientifically accurate as possible.
In theory, is racepinephrine (the active ingredient in Asthmanefrin) compatible as an emergency replacement for ...
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Citrate vs EDTA
What is the difference between the use of «citrate» and «EDTA» as an anticoagulant in medicine (I know that each one is used for some dosages but not the other, but I need to know why)?
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What is the expected life span of vascular stents?
What is the expected life span of vascular stents?
For example: Universal (coronary/venous) stent WALLSTENT-UNI Boston Scientific, metal: nitinol = titanium + nickel.
How many pulsating contractions ...
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