Questions tagged [medications]

Questions related to intake, use, safety, side effects, pharmacokinetics, pharmacodynamics, drugs, prodrugs and medication.

82 questions with no upvoted or accepted answers
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6
votes
1answer
345 views

Does taking medication lose hyperfocus on ADHD?

I wonder if taking medication to deal with unconcentration on ADHD would lose hyperfocus, which is considered one of the advantage of ADHD. I understand taking medication on ADHD have a side effect ...
5
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1answer
80 views

Using corticosteroids during pregnancy

I recently learned that steroids are sometimes given to mothers in preterm labor. For example: If a baby is at risk of being born too early, giving the mother steroids before the birth can help ...
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0answers
35 views

Why/how are some drugs nephrotoxic?

I want to know the (more or less) exact mechanism by which specific nephrotoxic medications damage the kidneys. For some drugs it seems relatively intuitive that they interfere with the function of ...
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44 views

How do drug companies know how to produce a generic drug?

Do the original companies have to reveal their manufacturing process to the public before they sell the drugs and the other companies can copy from them after their patent is expired?
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85 views

How does metformin interact with nicotine?

Does co-use of nicotine replacement therapy and metformin increase lactic acidosis risk? If so, how?
4
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92 views

Does long-term SSRI use cause any permanent changes in personality? Are there any quantitative/qualitative studies looking at this?

Curious about counseling patient's on the long-term risk/benefit analysis of SSRI use? Is there any EBM on what personality changes one should expect after X period of SSRI use? Does this change ...
3
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0answers
75 views

Must one take anticoagulants lifelong after stenting of deep veins with a non-thrombotic lesion?

Must one take anticoagulants lifelong after stenting of deep veins with a non-thrombotic lesion, for example, aorto-venous conflict (May-Thurner syndrome)? Or is it enough to take anticoagulants only ...
3
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0answers
44 views

Is benzoyl peroxide as body wash less effective than creams?

For severe acne, wouldn't it be most effective to contact and subject the affected areas to Benzoyl Peroxide (BPO) for as long as possible? If yes, then ought it not be applied as a cream? As a body ...
3
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0answers
121 views

Why are certain drugs prescribed more often to either males or females?

I have some original data on prescription frequencies of certain common drugs and I have calculated the gender ratio of patients for each. The list below contains Top 15 of the most commonly ...
3
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0answers
53 views

Do pharmaceuticals which increase dopamine and norepinephrine levels in the brain significantly increase histamine levels?

I imagine any medication that has an effect on catecholamines would in some way increase histamine levels as well, just for the fact that histamine is part of the 'fight or flight' response and seems ...
3
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0answers
32 views

What is the proper time to eat Vitamin B2 and B6?

I am usually told to take particular medicines before dinner or after dinner. Does this apply to Vitamin B2 and B6? More detailly, Should I eat them in 30 minutes near dinner (after longer time, ...
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46 views

Medicine/drug to “get along” with difficult people?

This is not a solicitation for medical advice. If I want a medical opinion I know I need to see a doctor. Are there specific medicines, drugs and/or substances which: are legal in the USA without a ...
3
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0answers
22 views

Is there a medical database with data (measured from patients) for research?

I am currently working on a mathematical project about optimisation problems in pharmacokinetics. To make it more practical and interesting, I was thinking of making some computations on actual data. ...
3
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0answers
23 views

Term for non-exposure-related tolerance?

"Tolerance" to a drug is typically interpreted to mean the state of requiring more of that drug to cause the same effects as compared to another individual, regardless of cause. However, the medical ...
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61 views

What are psychiatric effects of this herbal medicine?

Its is called Khamira Gaozaban Ambri.What could be its psychiatric effects, is it effective against phobias and fears? And is there any possible side effect of using this with Ginkgo Biloba?
3
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1answer
51 views

Storing pills together

How long can I store Magnesium Chloride tablets with my other medications? I use a one-week pill organizer and wonder if the water absorbing properties of the magnesium are a concern within that ...
2
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0answers
31 views

Why do antidepressant drugs increase body mass?

Serotonin is an anorexient neurotransmitter. But if I am right, antidepressant drugs like SSRIs increase the amount of serotonin in the brain. So why do antidepressants increase body mass if ...
2
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0answers
46 views

What exactly is the meaning of “No doping” sign on a drug package?

I noticed a "No doping" sign on the back of a pack of Dopamine HCl ampoules. It looks like this: I was wondering what is the purpose of this sign. I am guessing that it means that the drug should not ...
2
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0answers
36 views

Why was Ergotamine (trade name: Cafergot) discontinued in Canada and UK?

My mom in HK was prescribed Ergotamine, but I'm unnerved discontinuation in Canada and UK! Something wrong with it? Asked 13 Oct 2012 by lucyglitters i live in the uk and i've been taking it for ...
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0answers
46 views

What is the expected life span of vascular stents?

What is the expected life span of vascular stents? For example: Universal (coronary/venous) stent WALLSTENT-UNI Boston Scientific, metal: nitinol = titanium + nickel. How many pulsating contractions ...
2
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0answers
63 views

Can blood flow destroy part of the metal stent in 10 to 40 years?

If a part of the metal stent has not grown into a vessel, can this part of the stent be washed out by the blood flow in 10 to 40 years (theoretically)? Also are such cases known that blood flow ...
2
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0answers
22 views

Meaning of “potential pharmacogenetic characterisation might also be evaluated so that these syndromes are treated at an earlier age.”

This could be offtopic because this might be just a case of sloppy phrasing and a case of "asking to guess what the authors really meant". A quote from an abstract (GTP-cyclohydrolase deficiency ...
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56 views

hair repigmentation and growth from secukinumab

I saw this study(link) about a patient who received a drug called secukinumab and experienced hair re-pigmentation from white to black and hair re-growth and as you can see the results are pretty ...
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0answers
24 views

What's next after DMARD failure in rheumatoid arthritis?

Rheumatoid arthritis is a systemic disease that is most characterised by a progressive destructive joint disease that is traditionally managed with disease modifying drugs. If these fail to control ...
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0answers
26 views

Why do hemorrhoid medicines include moisturisers such as Witch's Hazel and Aloe Vera?

I read that Witch's Hazel is good as home remedy for hemorrhoid nodules and that it is sometimes a component of medicines. But Witch's Hazel creams are generally intended for the face. So what is the ...
2
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0answers
16 views

Is drug-based liver damage usually traceable to free radical generation?

From my fairly limited understanding, much of the time medications are said to be damaging to the liver, what is meant is that the process of breaking them down causes the formation of free radicals, ...
2
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0answers
99 views

Why are topical corticosteroids used in conjunction with an antiviral to treat herpes keratitis?

Herpes simplex keratitis is a viral infection of the eye. Topical antiviral medications are used to treat the virus. Corticosteroids ophthalmic drops are sometimes used as well. But corticosteroids ...
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0answers
150 views

What is the reason you can only take flucloxacillin on an empty stomach?

Is there a specific type of food that causes flucloxacillin to not be abosrbed more so than other kinds of food? Specifically could somebody eat for example a handful of almonds or peanuts as a small ...
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0answers
21 views

Is nurse prescribing limited to PGD medication?

Are nurse prescribers limited to giving PGD medication only? Or are there non-PGD medications they are permitted to prescribe? This question relates to NHS general hospitals in the UK.
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39 views

How does donepezil impact the immune system?

Is it immunosuppressive? If so, to what extent? What are the mechanisms for this effect?
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32 views

how does the immune system identify allergens? application: varenicline and lobeline

I'm wondering if we know how the immune system identifies allergens. My biochemistry knowledge is basic so I apologize if I use concepts incorrectly! Specifically, I want to know about the likelihood ...
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0answers
16 views

Do fiber pills interfere with prescrption medications?

Do fiber pills interfere with the absorption or efficacy of prescrption medications?
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0answers
245 views

Nootropics for epileptics

Hello guys! I'm epileptic and last months I have some problems with my attention and my memory. Another problem is, I'm from Russia and we don't have here good pills or really qualified doctors and ...
2
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0answers
341 views

How could Lyrica (pregabalin) cause hallucinations?

I've heard of this happening on rare occasion, but I cannot figure out a sensible mechanism. I have some limited understanding of neurology and the function of GABA, and I know that ethanol (a GABA ...
2
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0answers
122 views

What could be the reason for difference in adverse effects profile between original and generic Clopidogrel?

I was consulted on the following clinical case: An elderly woman (over 65 years old) on Plavix due to 2 CVAs in the last few years. Six months ago treatment was changed to a generic Clopidogrel ...
2
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0answers
59 views

Does an infected dental nerve affect nose breahting?

I went to my dentist for a lookup and he told me I needed a tooth canal treatment. He asked me if I had some problems with my nose, like if it's closed or dry. He was right about it and he told me the ...
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0answers
36 views

Is there a database for the drug formulation?

I am interested in the antibody formulation (e.g. concentration, salts, pH, excipients, etc.). I wonder if there is a database for that?
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0answers
8k views

Is there a difference between anti-anxiety and anti-depression drugs?

I've recently come across two terms "Anxiolytic drugs" and "Anti-depressant drugs". I wanted to know how they differ from each other; if they do. I mean, sure, "anxiety" isn't the same as "depression"...
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0answers
74 views

Is the common cold deadly to a suppressed immune system?

If you were taking an immune system suppressant such as Prograf (Tacrolimus) for a long period of time would a virus like the common cold linger in the body and cause infection over time and possibly ...
2
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0answers
25 views

can 5 alpha reductase inhibitor drugs work for life or do they lose effectivness

does 5 alpha reductase inhibitor drugs like finasteride and dutasteride losses their effectiveness over time, and why do some drugs like Hiv regimen work prolonged time without tolerance and other ...
2
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0answers
57 views

Is there a good site for drug reviews?

I have have it difficult to research the drugs I am prescribed. I was wondering if there are any websites that are good sources for reviews concerning drugs. I have no idea how to find a trustworthy ...
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0answers
169 views

Epidural and cholinesterase deficiency

I have pseudocholinesterase deficiency (BCHE gene), but my wife does not. My wife may need/strongly desire an epidural for our next child. Is this safe for a fetus which may possibly have the same ...
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0answers
19 views

How do you know if an over the counter drug is safely processed and safe to use?

How do you know if an over the counter drug is safely processed and safe to use? I have not heard of the brand SDA Laboratories before, so tried searching online to see if it has any safety ...
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0answers
23 views

Where can I find a list (even if only partial) of excipients that cause a medication to be indivisible?

Certain tablet formulations should not be divided or halved because the tablets are film-coated for low pH resistance (i.e. for safe passage in the stomach) or because the active ingredient is not ...
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1answer
70 views

What is the difference between Dry cough, Wet cough, Chesty Cough, Barking cough?

I am doing some research on cough sounds but my background is not health sector and I am facing issues to identify the correct type of cough. I have two doubts : Is chesty cough Wet cough? Is ...
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0answers
30 views

Why is Toradol no longer available in the US?

A few years ago I was given Toradol for kidney stone pain. It was magical. My friend just had a kidney stone and was given morphine, then Dilaudid. Curious about the differences, I went googling, only ...
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0answers
21 views

Cancer treatment through regulation of myeloid-derived suppressor cells

There are many ongoing clinical trials that leverage the power of the immune system to recognize tumor cells such as CD47 and PDL1/PD1, and even engineered T cells! I ran across an immune cell type ...
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0answers
26 views

Why do most drugs target G-protein receptors?

I've read that more than 50% drugs target the g-protein coupled receptors: What is so special with them that they are the targets for such a wide range of diseases?
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0answers
34 views

Can marigold extract be used in mosquito repellent ointment?

I am doing research on mosquito repellent as a part of my college project. I have found various sources of marigold being used as insect repellent such as the following link- https://www.ncbi.nlm....
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0answers
33 views

Where can I find the original brand names of every psychotropic medication?

I'm looking for a place to find the original (initial) brand name of every psychotropic medication when it was first introduced (internationally, not necessarily in the US). I'm not interested in ...