Questions tagged [medications]

Questions related to intake, use, safety, side effects, pharmacokinetics, or any other aspect of a drug prescribed by a physician.

70 questions with no upvoted or accepted answers
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6
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1answer
281 views

Does taking medication lose hyperfocus on ADHD?

I wonder if taking medication to deal with unconcentration on ADHD would lose hyperfocus, which is considered one of the advantage of ADHD. I understand taking medication on ADHD have a side effect ...
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108 views

Do proton pump inhibitors (PPI's) shut down all the proton pumps in all cells across our body system?

It's known that proton pumps exist in all cells in our bodies and help us to get rid of damaged proteins (present a disposal system). PPIs (omeprazole, pantoprazole, esomeprazole, lansoprazole and ...
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39 views

What are the long term effects of using diclofenac patches?

I wonder what the long term effects are of using diclofenac patches (e.g. one patch applied daily and kept for 24 hours positioned on the lateral epicondyle of the humerus). By long term I mean ...
5
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1answer
75 views

Using corticosteroids during pregnancy

I recently learned that steroids are sometimes given to mothers in preterm labor. For example: If a baby is at risk of being born too early, giving the mother steroids before the birth can help ...
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90 views

Does long-term SSRI use cause any permanent changes in personality? Are there any quantitative/qualitative studies looking at this?

Curious about counseling patient's on the long-term risk/benefit analysis of SSRI use? Is there any EBM on what personality changes one should expect after X period of SSRI use? Does this change ...
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30 views

Why/how are some drugs nephrotoxic?

I want to know the (more or less) exact mechanism by which specific nephrotoxic medications damage the kidneys. For some drugs it seems relatively intuitive that they interfere with the function of ...
3
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75 views

Must one take anticoagulants lifelong after stenting of deep veins with a non-thrombotic lesion?

Must one take anticoagulants lifelong after stenting of deep veins with a non-thrombotic lesion, for example, aorto-venous conflict (May-Thurner syndrome)? Or is it enough to take anticoagulants only ...
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44 views

Is benzoyl peroxide as body wash less effective than creams?

For severe acne, wouldn't it be most effective to contact and subject the affected areas to Benzoyl Peroxide (BPO) for as long as possible? If yes, then ought it not be applied as a cream? As a body ...
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105 views

Why are certain drugs prescribed more often to either males or females?

I have some original data on prescription frequencies of certain common drugs and I have calculated the gender ratio of patients for each. The list below contains Top 15 of the most commonly ...
3
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39 views

Why does anybody still prescribe Citalopram with Escitalopram available (apart from price)?

As far as I could find Escitalopram is superior in every way, except for the US price (which might no longer even be the case). So why is the former still widely used worldwide? Did I miss anything? ...
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32 views

What is the proper time to eat Vitamin B2 and B6?

I am usually told to take particular medicines before dinner or after dinner. Does this apply to Vitamin B2 and B6? More detailly, Should I eat them in 30 minutes near dinner (after longer time, ...
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40 views

How do drug companies know how to produce a generic drug?

Do the original companies have to reveal their manufacturing process to the public before they sell the drugs and the other companies can copy from them after their patent is expired?
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43 views

Medicine/drug to “get along” with difficult people?

This is not a solicitation for medical advice. If I want a medical opinion I know I need to see a doctor. Are there specific medicines, drugs and/or substances which: are legal in the USA without a ...
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19 views

Is there a medical database with data (measured from patients) for research?

I am currently working on a mathematical project about optimisation problems in pharmacokinetics. To make it more practical and interesting, I was thinking of making some computations on actual data. ...
3
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1answer
45 views

Mechanism of Metformin in Lactic Acidosis

High dosages of metformin and other biguanides are liked to lactic acidosis. What is the pharmacological mechanism behind this? I am aware the people have survived doses as high as 63 grams, but at ...
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23 views

Term for non-exposure-related tolerance?

"Tolerance" to a drug is typically interpreted to mean the state of requiring more of that drug to cause the same effects as compared to another individual, regardless of cause. However, the medical ...
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60 views

What are psychiatric effects of this herbal medicine?

Its is called Khamira Gaozaban Ambri.What could be its psychiatric effects, is it effective against phobias and fears? And is there any possible side effect of using this with Ginkgo Biloba?
3
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1answer
51 views

Storing pills together

How long can I store Magnesium Chloride tablets with my other medications? I use a one-week pill organizer and wonder if the water absorbing properties of the magnesium are a concern within that ...
3
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1answer
198 views

Is there any alternative to Accutane for acne treatment?

I have had acne for 4 years straight and it has been getting worse and worse, ever since. I've tried every trick in the book: Tea tree oil Benzoyl Peroxide Retin A (0.025%; 0.05%; 0.1%) ...
2
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0answers
33 views

Why was Ergotamine (trade name: Cafergot) discontinued in Canada and UK?

My mom in HK was prescribed Ergotamine, but I'm unnerved discontinuation in Canada and UK! Something wrong with it? Asked 13 Oct 2012 by lucyglitters i live in the uk and i've been taking it for ...
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44 views

What is the expected life span of vascular stents?

What is the expected life span of vascular stents? For example: Universal (coronary/venous) stent WALLSTENT-UNI Boston Scientific, metal: nitinol = titanium + nickel. How many pulsating contractions ...
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62 views

Can blood flow destroy part of the metal stent in 10 to 40 years?

If a part of the metal stent has not grown into a vessel, can this part of the stent be washed out by the blood flow in 10 to 40 years (theoretically)? Also are such cases known that blood flow ...
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22 views

Meaning of “potential pharmacogenetic characterisation might also be evaluated so that these syndromes are treated at an earlier age.”

This could be offtopic because this might be just a case of sloppy phrasing and a case of "asking to guess what the authors really meant". A quote from an abstract (GTP-cyclohydrolase deficiency ...
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52 views

hair repigmentation and growth from secukinumab

I saw this study(link) about a patient who received a drug called secukinumab and experienced hair re-pigmentation from white to black and hair re-growth and as you can see the results are pretty ...
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24 views

What's next after DMARD failure in rheumatoid arthritis?

Rheumatoid arthritis is a systemic disease that is most characterised by a progressive destructive joint disease that is traditionally managed with disease modifying drugs. If these fail to control ...
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25 views

Why do hemorrhoid medicines include moisturisers such as Witch's Hazel and Aloe Vera?

I read that Witch's Hazel is good as home remedy for hemorrhoid nodules and that it is sometimes a component of medicines. But Witch's Hazel creams are generally intended for the face. So what is the ...
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15 views

Is drug-based liver damage usually traceable to free radical generation?

From my fairly limited understanding, much of the time medications are said to be damaging to the liver, what is meant is that the process of breaking them down causes the formation of free radicals, ...
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98 views

Why are topical corticosteroids used in conjunction with an antiviral to treat herpes keratitis?

Herpes simplex keratitis is a viral infection of the eye. Topical antiviral medications are used to treat the virus. Corticosteroids ophthalmic drops are sometimes used as well. But corticosteroids ...
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141 views

What is the reason you can only take flucloxacillin on an empty stomach?

Is there a specific type of food that causes flucloxacillin to not be abosrbed more so than other kinds of food? Specifically could somebody eat for example a handful of almonds or peanuts as a small ...
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21 views

Is nurse prescribing limited to PGD medication?

Are nurse prescribers limited to giving PGD medication only? Or are there non-PGD medications they are permitted to prescribe? This question relates to NHS general hospitals in the UK.
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37 views

How does donepezil impact the immune system?

Is it immunosuppressive? If so, to what extent? What are the mechanisms for this effect?
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32 views

how does the immune system identify allergens? application: varenicline and lobeline

I'm wondering if we know how the immune system identifies allergens. My biochemistry knowledge is basic so I apologize if I use concepts incorrectly! Specifically, I want to know about the likelihood ...
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16 views

Do fiber pills interfere with prescrption medications?

Do fiber pills interfere with the absorption or efficacy of prescrption medications?
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0answers
227 views

Nootropics for epileptics

Hello guys! I'm epileptic and last months I have some problems with my attention and my memory. Another problem is, I'm from Russia and we don't have here good pills or really qualified doctors and ...
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0answers
325 views

How could Lyrica (pregabalin) cause hallucinations?

I've heard of this happening on rare occasion, but I cannot figure out a sensible mechanism. I have some limited understanding of neurology and the function of GABA, and I know that ethanol (a GABA ...
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108 views

What could be the reason for difference in adverse effects profile between original and generic Clopidogrel?

I was consulted on the following clinical case: An elderly woman (over 65 years old) on Plavix due to 2 CVAs in the last few years. Six months ago treatment was changed to a generic Clopidogrel ...
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59 views

Does an infected dental nerve affect nose breahting?

I went to my dentist for a lookup and he told me I needed a tooth canal treatment. He asked me if I had some problems with my nose, like if it's closed or dry. He was right about it and he told me the ...
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36 views

Is there a database for the drug formulation?

I am interested in the antibody formulation (e.g. concentration, salts, pH, excipients, etc.). I wonder if there is a database for that?
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8k views

Is there a difference between anti-anxiety and anti-depression drugs?

I've recently come across two terms "Anxiolytic drugs" and "Anti-depressant drugs". I wanted to know how they differ from each other; if they do. I mean, sure, "anxiety" isn't the same as "depression"...
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61 views

Is the common cold deadly to a suppressed immune system?

If you were taking an immune system suppressant such as Prograf (Tacrolimus) for a long period of time would a virus like the common cold linger in the body and cause infection over time and possibly ...
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0answers
24 views

can 5 alpha reductase inhibitor drugs work for life or do they lose effectivness

does 5 alpha reductase inhibitor drugs like finasteride and dutasteride losses their effectiveness over time, and why do some drugs like Hiv regimen work prolonged time without tolerance and other ...
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0answers
57 views

Is there a good site for drug reviews?

I have have it difficult to research the drugs I am prescribed. I was wondering if there are any websites that are good sources for reviews concerning drugs. I have no idea how to find a trustworthy ...
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0answers
155 views

Epidural and Cholinesterase Deficiency

I have pseudocholinesterase deficiency (BCHE gene), but my wife does not. My wife may need/strongly desire an epidural for our next child. Is this safe for a fetus which may possibly have the same ...
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33 views

Where can I find the original brand names of every psychotropic medication?

I'm looking for a place to find the original (initial) brand name of every psychotropic medication when it was first introduced (internationally, not necessarily in the US). I'm not interested in ...
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0answers
29 views

How does the med, Spironolactone, help with PCOS?

I've been taking Spironolactone for my acne for many years (I'm a woman in my late 20's now). I have been taking it for this intended purpose. The other day, a doctor was looking over my meds and for ...
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50 views

Are supplements like Glucosamine permanent or temporary?

I've been into body building for the last 25 years, and my joints are in poor shape. There are things made for sore joints like Glucosamine Sulfate and Turmeric Curcumin that get great reviews. But ...
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0answers
25 views

What is the mechanism of acute caffeine tolerance?

I'll admit this curiosity is based on a personal experience I'll document here, but I do believe it's an interesting and useful academic question to study and explore. For a while, I've noticed that ...
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0answers
45 views

Why do some medications have HCl?

I have seen a lot of medications including a few that I take for certain situations. 1 of the medications that I occasionally take is Benadryl. The main component of this is Diphenhydramine HCl. I ...
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50 views

Why is Chlorprothixene not approved for use in the United States?

The medicament Chlorprothixene has been around since 1959. Why is it not approved for use in the United States?
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23 views

What is a PAINs (pan-assay interference compounds)? How do you prove that a compound is a PAIN? And IMPs (invalid metabolic compund)?

I've been reading about curcumin and it seems to have been pretty useful in numerous clinical trials (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535097/), although its biodisponibility is "abysmal" ...