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Questions tagged [medications]

Questions related to intake, use, safety, side effects, pharmacokinetics, pharmacodynamics, drugs, prodrugs and medication.

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Using corticosteroids during pregnancy

I recently learned that steroids are sometimes given to mothers in preterm labor. For example: If a baby is at risk of being born too early, giving the mother steroids before the birth can help ...
YviDe's user avatar
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Do topical anti-inflamatory preparations work topically?

There are topical anti-inflamatory preparations where the advertising at least implies that they work topically, in that the effect will be more localised by the use of a topical preparation than if ...
User65535's user avatar
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Why/how are some drugs nephrotoxic?

I want to know the (more or less) exact mechanism by which specific nephrotoxic medications damage the kidneys. For some drugs it seems relatively intuitive that they interfere with the function of ...
Lukeception's user avatar
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206 views

Why are certain drugs prescribed more often to either males or females?

I have some original data on prescription frequencies of certain common drugs and I have calculated the gender ratio of patients for each. The list below contains Top 15 of the most commonly ...
Mihail's user avatar
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How do drug companies know how to produce a generic drug?

Do the original companies have to reveal their manufacturing process to the public before they sell the drugs and the other companies can copy from them after their patent is expired?
ronenfe's user avatar
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How does metformin interact with nicotine?

Does co-use of nicotine replacement therapy and metformin increase lactic acidosis risk? If so, how?
user16520's user avatar
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Does long-term SSRI use cause any permanent changes in personality? Are there any quantitative/qualitative studies looking at this?

Curious about counseling patient's on the long-term risk/benefit analysis of SSRI use? Is there any EBM on what personality changes one should expect after X period of SSRI use? Does this change ...
Basmaster 's user avatar
3 votes
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Does treatment with one triazole give resistance to all other triazoles?

Let's say a patient is treated with a triazole (e.g. Itraconazole) for an oral thrush infection and the fungus acquires resistance to it, then is that resistance against other triazoles too (e.g. ...
user96551's user avatar
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Why can't Asian flush be treated in a similar way to lactose intolerance?

I have been reading about the Asian flush, which is caused by a histamine reaction to a toxic byproduct of alcohol metabolism, acetaldehyde. Some individuals are able to suppress the histamine ...
Jacob T's user avatar
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Must one take anticoagulants lifelong after stenting of deep veins with a non-thrombotic lesion?

Must one take anticoagulants lifelong after stenting of deep veins with a non-thrombotic lesion, for example, aorto-venous conflict (May-Thurner syndrome)? Or is it enough to take anticoagulants only ...
Alex's user avatar
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Do pharmaceuticals which increase dopamine and norepinephrine levels in the brain significantly increase histamine levels?

I imagine any medication that has an effect on catecholamines would in some way increase histamine levels as well, just for the fact that histamine is part of the 'fight or flight' response and seems ...
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What is the proper time to eat Vitamin B2 and B6?

I am usually told to take particular medicines before dinner or after dinner. Does this apply to Vitamin B2 and B6? More detailly, Should I eat them in 30 minutes near dinner (after longer time, ...
Mithril's user avatar
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Medicine/drug to "get along" with difficult people?

This is not a solicitation for medical advice. If I want a medical opinion I know I need to see a doctor. Are there specific medicines, drugs and/or substances which: are legal in the USA without a ...
Patrick87's user avatar
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Is there a medical database with data (measured from patients) for research?

I am currently working on a mathematical project about optimisation problems in pharmacokinetics. To make it more practical and interesting, I was thinking of making some computations on actual data. ...
Jan's user avatar
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Nootropics for epileptics

Hello guys! I'm epileptic and last months I have some problems with my attention and my memory. Another problem is, I'm from Russia and we don't have here good pills or really qualified doctors and ...
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Term for non-exposure-related tolerance?

"Tolerance" to a drug is typically interpreted to mean the state of requiring more of that drug to cause the same effects as compared to another individual, regardless of cause. However, the medical ...
TheEnvironmentalist's user avatar
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62 views

What are psychiatric effects of this herbal medicine?

Its is called Khamira Gaozaban Ambri.What could be its psychiatric effects, is it effective against phobias and fears? And is there any possible side effect of using this with Ginkgo Biloba?
Dombie's user avatar
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Storing pills together

How long can I store Magnesium Chloride tablets with my other medications? I use a one-week pill organizer and wonder if the water absorbing properties of the magnesium are a concern within that ...
Camille's user avatar
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Are there medications that treat premature ejaculation without interfering in serotonin levels?

The widespread medications that are being used to treat premature ejaculation (PE) are kind of antidepressants called SSRIs (Selective Serotonin Reuptake Inhibitors). But the problem with this kind of ...
Snack Exchange's user avatar
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43 views

Why do antidepressant drugs increase body mass?

Serotonin is an anorexient neurotransmitter. But if I am right, antidepressant drugs like SSRIs increase the amount of serotonin in the brain. So why do antidepressants increase body mass if ...
Positron12's user avatar
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Where can I find a list (even if only partial) of excipients that cause a medication to be indivisible?

Certain tablet formulations should not be divided or halved because the tablets are film-coated for low pH resistance (i.e. for safe passage in the stomach) or because the active ingredient is not ...
Don_S's user avatar
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What exactly is the meaning of "No doping" sign on a drug package?

I noticed a "No doping" sign on the back of a pack of Dopamine HCl ampoules. It looks like this: I was wondering what is the purpose of this sign. I am guessing that it means that the drug should not ...
Don_S's user avatar
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2 votes
0 answers
70 views

What is the expected life span of vascular stents?

What is the expected life span of vascular stents? For example: Universal (coronary/venous) stent WALLSTENT-UNI Boston Scientific, metal: nitinol = titanium + nickel. How many pulsating contractions ...
Alex's user avatar
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Can blood flow destroy part of the metal stent in 10 to 40 years?

If a part of the metal stent has not grown into a vessel, can this part of the stent be washed out by the blood flow in 10 to 40 years (theoretically)? Also are such cases known that blood flow ...
Alex's user avatar
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Meaning of "potential pharmacogenetic characterisation might also be evaluated so that these syndromes are treated at an earlier age."

This could be offtopic because this might be just a case of sloppy phrasing and a case of "asking to guess what the authors really meant". A quote from an abstract (GTP-cyclohydrolase deficiency ...
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hair repigmentation and growth from secukinumab

I saw this study(link) about a patient who received a drug called secukinumab and experienced hair re-pigmentation from white to black and hair re-growth and as you can see the results are pretty ...
petrichor's user avatar
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59 views

Are supplements like Glucosamine permanent or temporary?

I've been into body building for the last 25 years, and my joints are in poor shape. There are things made for sore joints like Glucosamine Sulfate and Turmeric Curcumin that get great reviews. But ...
jp2code's user avatar
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0 answers
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What's next after DMARD failure in rheumatoid arthritis?

Rheumatoid arthritis is a systemic disease that is most characterised by a progressive destructive joint disease that is traditionally managed with disease modifying drugs. If these fail to control ...
Graham Chiu's user avatar
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29 views

Why do hemorrhoid medicines include moisturisers such as Witch's Hazel and Aloe Vera?

I read that Witch's Hazel is good as home remedy for hemorrhoid nodules and that it is sometimes a component of medicines. But Witch's Hazel creams are generally intended for the face. So what is the ...
user2617804's user avatar
2 votes
0 answers
18 views

Is drug-based liver damage usually traceable to free radical generation?

From my fairly limited understanding, much of the time medications are said to be damaging to the liver, what is meant is that the process of breaking them down causes the formation of free radicals, ...
TheEnvironmentalist's user avatar
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102 views

Why are topical corticosteroids used in conjunction with an antiviral to treat herpes keratitis?

Herpes simplex keratitis is a viral infection of the eye. Topical antiviral medications are used to treat the virus. Corticosteroids ophthalmic drops are sometimes used as well. But corticosteroids ...
Nectar's user avatar
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0 answers
359 views

What is the reason you can only take flucloxacillin on an empty stomach?

Is there a specific type of food that causes flucloxacillin to not be abosrbed more so than other kinds of food? Specifically could somebody eat for example a handful of almonds or peanuts as a small ...
kiltannen's user avatar
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2 votes
0 answers
23 views

Is nurse prescribing limited to PGD medication?

Are nurse prescribers limited to giving PGD medication only? Or are there non-PGD medications they are permitted to prescribe? This question relates to NHS general hospitals in the UK.
Ne Mo's user avatar
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0 answers
44 views

How does donepezil impact the immune system?

Is it immunosuppressive? If so, to what extent? What are the mechanisms for this effect?
user16520's user avatar
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2 votes
0 answers
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how does the immune system identify allergens? application: varenicline and lobeline

I'm wondering if we know how the immune system identifies allergens. My biochemistry knowledge is basic so I apologize if I use concepts incorrectly! Specifically, I want to know about the likelihood ...
beepbeep's user avatar
2 votes
0 answers
18 views

Do fiber pills interfere with prescrption medications?

Do fiber pills interfere with the absorption or efficacy of prescrption medications?
End Antisemitic Hate's user avatar
2 votes
0 answers
578 views

How could Lyrica (pregabalin) cause hallucinations?

I've heard of this happening on rare occasion, but I cannot figure out a sensible mechanism. I have some limited understanding of neurology and the function of GABA, and I know that ethanol (a GABA ...
Sasha's user avatar
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2 votes
0 answers
143 views

What could be the reason for difference in adverse effects profile between original and generic Clopidogrel?

I was consulted on the following clinical case: An elderly woman (over 65 years old) on Plavix due to 2 CVAs in the last few years. Six months ago treatment was changed to a generic Clopidogrel ...
Don_S's user avatar
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2 votes
0 answers
62 views

Does an infected dental nerve affect nose breahting?

I went to my dentist for a lookup and he told me I needed a tooth canal treatment. He asked me if I had some problems with my nose, like if it's closed or dry. He was right about it and he told me the ...
user387171's user avatar
2 votes
0 answers
38 views

Is there a database for the drug formulation?

I am interested in the antibody formulation (e.g. concentration, salts, pH, excipients, etc.). I wonder if there is a database for that?
lanselibai's user avatar
2 votes
0 answers
8k views

Is there a difference between anti-anxiety and anti-depression drugs?

I've recently come across two terms "Anxiolytic drugs" and "Anti-depressant drugs". I wanted to know how they differ from each other; if they do. I mean, sure, "anxiety" isn't the same as "depression"...
paracetamol's user avatar
2 votes
0 answers
79 views

Is the common cold deadly to a suppressed immune system?

If you were taking an immune system suppressant such as Prograf (Tacrolimus) for a long period of time would a virus like the common cold linger in the body and cause infection over time and possibly ...
David Saunders's user avatar
2 votes
0 answers
30 views

can 5 alpha reductase inhibitor drugs work for life or do they lose effectivness

does 5 alpha reductase inhibitor drugs like finasteride and dutasteride losses their effectiveness over time, and why do some drugs like Hiv regimen work prolonged time without tolerance and other ...
h.hamid's user avatar
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2 votes
0 answers
60 views

Is there a good site for drug reviews?

I have have it difficult to research the drugs I am prescribed. I was wondering if there are any websites that are good sources for reviews concerning drugs. I have no idea how to find a trustworthy ...
user avatar
2 votes
0 answers
209 views

Epidural and cholinesterase deficiency

I have pseudocholinesterase deficiency (BCHE gene), but my wife does not. My wife may need/strongly desire an epidural for our next child. Is this safe for a fetus which may possibly have the same ...
haleonj's user avatar
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1 vote
0 answers
8 views

How to handle inverse agonism when calculating bias?

Is there a standard way to compare an inverse agonist to an agonist in a bias calculation? The problem is that inverse agonists have negative efficacy, so you can't take the log to calculate RA... ...
user26943's user avatar
1 vote
0 answers
49 views

What is the state of transmissible vaccines?

I was thinking about viral gain of function research -- and firebugs playing with matches -- when it hit me: if a highly contagious, but harmless version were engineered it could outcompete more ...
thegreatwhatsit's user avatar
1 vote
0 answers
39 views

Does Remdesivir really go bad after reconstitution with sterile water?

I was recently looking at how long can Remdesivir be stored in its different forms. I came up across several articles provided by the FDA and Gilead Sciences and others. What caught my eye was the ...
ATheCoder's user avatar
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1 vote
0 answers
19 views

Effects of anti-Rh(D) antibodies on the fetus

Rh disease is caused by the irruption in the fetal circulation of anti-Rh(D) antibodies. This only happens when there has been a prior exposure of the mother to Rh+ RBC. To prevent Rh sensitization ...
user47679's user avatar
1 vote
0 answers
33 views

Tick bite treatment. Doxycycline intake suspended after 3 days only. If substituted by Bactrim, is there a risk to develop bacteria resistant?

A patient was bitten by a tick and carried the tick on his skin for 5/6 days (which got engorged at the end). Then the tick dropped spontaneously. He has been prescribed a preventive antibiotic course ...
NikoEraser's user avatar