Questions tagged [endocrinology]

The branch of physiology and medicine concerned with endocrine glands and hormones.

Filter by
Sorted by
Tagged with
0
votes
0answers
18 views

What is the rationale of using Metformin in Pre-Diabetes and Non-Insulin-Dependent Diabetes?

Mechanism of action of Metformin is Ultimately, it decreases gluconeogenesis (glucose production) in the liver Gluconeogenesis results from breaking up of fat. Metformin also inhibits cellular ...
1
vote
1answer
189 views

Acceptable Macronutrient Distribution Range

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674146/ I found some papers suggesting AMDR is not the optimum and it is too high on carbohydrates in particular. Is it generally safe to undergo a 27....
0
votes
1answer
23 views

Different names for HbA1c

Am a data analyst working on healthcare data analysis. I came across the below terms in my source data from the hospital system. I did a google search and found that they all are the same Glycated HB ...
0
votes
1answer
23 views

How human placental lactogen (hPL) is associated with insulin resistance in pregnancy?

I am unable to understand the molecular mechanism of hPL induced insulin resistance. Sharing of relevant article/text would be of immense help.
6
votes
1answer
76 views

How long would it take for one's thyroid hormones to get to dangerously low levels?

If the thyroid gland just completely stopped working and it went untreated, how long would it take for one's thyroid hormones to get to dangerously low levels? At what point does Myxedema Coma occur?
4
votes
0answers
34 views

Breakthrough bleeding on progestogen-only contraception

Background In hormonal contraception, two types of hormones are used; estrogens and progestogens. The progestogens are the type of hormone that is mainly responsible for the contraceptive effects. ...
0
votes
2answers
52 views

Why does adenosine processing require unconsciousness?

I've heard that one of the purposes of sleep is to process adenosine that builds up from metabolic processes, and it makes sense that the effect of adenosine as a neurotransmitter is to produce ...
1
vote
0answers
18 views

Why is cushing's syndrome mainly associated with cortisol?

When I hear Cushing's I always hear and think of cortisol excess. How come its cortisol that is mainly associated with this condition - more than mineralogical/ aldosterone or androgens? I ...
1
vote
2answers
423 views

How much melatonin does the body produce naturally per day?

Melatonin supplements are readily available over-the-counter. However, the dosage is not regulated and there are supplements available in a wide variety of doses. Information on how much melatonin ...
8
votes
1answer
352 views

What happens to a woman if she takes testosterone?

I'm interested in the changes that happen to the female body (let's say this person is 20) in the short (year one to five) and in the long term (20+ years). Let's assume that the dose of testosterone ...
5
votes
2answers
67 views

Does a hormone PTSH exist?

It's known that a hormone called TSH (thyroid stimulate hormone) does exist and it's secreted in the pituitary gland. But my question is about a hormone which secreted from the pituitary gland too ...
1
vote
0answers
26 views

Does premenstrual tension/stress persist after menopause?

"Premenstral stress/tension" (PMS/PMT) as commonly defined does exist I don't want to upset anyone by downplaying the real effects of PMT/PMS. Reports such as those pointed out by the NHS aside, I ...
1
vote
1answer
46 views

Impact of Various “Feminizing” Hormones on Metabolism

I've read that progesterone is linked to changes in metabolism and appetite, and that those undergoing hormone therapy with progesterone often experience profound changes in hunger and meal habits. I ...
1
vote
0answers
24 views

Safety of low dose testosterone therapy on biologically female individuals?

With the raising awareness about gender identity and specifically the recognition of non-binary identities, new challenges are faced by medicine. Specifically, there are individuals who don't feel ...
6
votes
1answer
8k views

Is there any risk from eating meals before/after HGH shots?

I'm undergoing HGH therapy, and I see a lot of conflicting information on the internet another whether or not it's truly bad to eat meals after/before the shots -- supposedly, it can increase the risk ...
1
vote
0answers
16 views

Which hormonal treatments have been shown to be useful to prevent or treat tendinopathies?

Which hormonal treatments have been shown to be useful to prevent or treat tendinopathies? {1} surveyed the links between hormones and tendinopathies but their main conclusion is: The influence of ...
2
votes
0answers
31 views

What advanced detection schemes can provide low cost screening for Latent Autoimmune Diabetes?

Latent Autoimmune Diabetes in Adults (LADA) may be more prevalent than previously believed. A common marker for the most common form is glutamic acid decarboxylase 65 (GAD-65). Are there low cost and ...
2
votes
0answers
42 views

What metric is used to measure estrogen levels?

I have had a blood test recently and over the phone I was told by a doctorthat my oestrogen level is high. I'm a man and was told my level is "190, but the average is 150". 190 what? I forgot to ask ...
5
votes
2answers
199 views

“There is a very strong correlation between consuming dairy products — such as milk — and acne, skin breakouts and aging.”

I read an article here that says: “There is a very strong correlation between consuming dairy products — such as milk — and acne, skin breakouts and aging.” The reason? Hormones, Bella says. ...
5
votes
1answer
86 views

Could a high TSH level mean a problem with the pituitary gland?

When our physician suspects we might have a problem with our thyroid he sends us to check the TSH level in our blood. If there is a lot of TSH in the blood it means that the thyroid can't work quickly ...
2
votes
0answers
34 views

Is lean non-hyperandrogenic polycystic ovary syndrome genetic?

I read many papers that address the genetic factor of polycystic ovary syndrome (PCOS). But all the papers I have been through focus on classic PCOS with hyperparathyroidism and insulin resistance. I ...
5
votes
1answer
96 views

Eczema and steroids: why do endogenous cortisol and exogenous cortisone/prednisone differ?

Topical steroids are a mainstay treatment for eczema, and severe episodes are sometimes treated with oral steroids. Meanwhile stress is a known trigger for exacerbating eczema. During physiological ...
6
votes
1answer
192 views

Is adrenaline a coctail of hormones, rather than one hormone?

Although it has been called the "Fight or Flight Hormone" adrenaline can be better described as 'Do it NOW!!! hormones." First things first, notice the 's.' Adrenaline isn't just one thing, but a ...
3
votes
0answers
30 views

Effects of hypophosphatemia on DNA

There is a lot of supportive evidence that its role in ATP results in much of the clinical manifestation of hypophosphatemia, but I was wondering about the other roles where Phosphate is an important ...
4
votes
0answers
39 views

Effectiveness of blue light filters for preventing delayed and decreased melatonin secretion?

The iPhone offers a "night shift" feature. Research indicates that blue light exposure decreases melatonin secretion (e.g., Ferguson, Melton, Li, Park, & Tosini, 2008). To what extent do built-...
3
votes
0answers
38 views

Causes for elevated beta-HCG and AFP

I am interested in finding possible causes of elevated levels of beta-HCG and Alpha-1-Fetoprotein in males. However, as much as I see, the only answer I find relates to cancer, and my curiosity is ...
6
votes
0answers
44 views

What is the link between elevated estrogen and lowered alkaline phosphatase?

This Wikipdia-article lists several conditions or diseases that may lead to reduced levels of alkaline phosphatase (AP). Among them are: postmenopausal women receiving estrogen therapy because of ...
1
vote
0answers
25 views

Can removing a contraceptive implant cause secondary amenorrhea?

When a woman stops taking birth control medication, she might suffer from various side effects. Can secondary amenorrhea (i.e. missing periods for more than 3 months) be induced by the removal of a ...
7
votes
1answer
131 views

Does elevated potassium lead to elevated cortisol?

I came across this statement on Selfhacked: If you have high cortisol, you will do worse with a high salt diet and you will be potassium deficient in the long term (few people as it is get the RDA)...
11
votes
1answer
164 views

“Narrow” Pure Androgen-secreting Adrenocortical Adenoma

I was looking for a case report or example to match something I've come across that I thought highly unlikely to the point of being untrue. That is a adrenocortical adenoma (AA) was functional but ...
2
votes
0answers
38 views

What are the changes of diamine oxidase (DAO)-activity with different sex hormones?

Based on this question: What happens to a woman if she takes testosterone? i have another question and would like to know more - that's because i've stumbled over this: DAO activity in tissues of ...
0
votes
1answer
74 views

Can an elevated TSH and normal T3 and T4 biologically cause fatigue?

I understand that if the levels of T3 and T4 are lower than normal, that this could directly lead to fatigue since these hormones directly regulate metabolism inside every cell. But is there an ...
4
votes
0answers
86 views

How does metformin interact with nicotine?

Does co-use of nicotine replacement therapy and metformin increase lactic acidosis risk? If so, how?
6
votes
1answer
568 views

What does metformin do to treat polycystic ovarian syndrome?

Metformin is a drug used to treat diabetes but one of its off-label uses is to treat Polycystic Ovarian Syndrome. What does metformin do for someone who has PCOS but does not have diabetes? Is ...
3
votes
0answers
119 views

What are the testosterone tests that I can take to prove that my low libido is really a testosterone problem?

I understand that ( correct me if I am wrong) the Sex Hormone Binding Globulin ( SHBG) test is one of the tests that can be used to evaluate one's libido. The sex hormone binding globulin (SHBG) ...
4
votes
1answer
4k views

Why Dydrogesterone is no longer available in US? Why dienogest is not approved?

Dydrogesterone and Dienogest are very very helpful medications in treating endometriosis condition, and Dydrogesterone helps many women to become pregnant. They are widely used around the world and ...
9
votes
1answer
1k views

Does hyperthyroidism affect serotonin levels?

I have read that hyperthyroidism can cause depression. Is this because of low serotonin levels or is there is another cause? Does this kind of depression need to be checked by a psychiatrist? Edit (...
9
votes
1answer
170 views

Does inhibiting prolactin levels cause any health problems?

I am using a prolactin inhibitor drug called "Dostinex". In general, it has some positive effects on me (increased libido, better mood) and I haven't realized any bad side effects. I'm wondering, ...
4
votes
0answers
20 views

transdermal estrogen use sans progesterone & endometrial and breast cancer risk?

To what extent does transdermal estrogen use, without co-use of progesterone, increase endometrial and breast cancer risk? How does risk, if it exists correlate with years of use?
9
votes
1answer
193 views

Hashimoto thyroiditis leading to severe psychological problems and behavior changes?

Can Hashimoto thyroiditis lead to psychological problems and severe behavioral changes? Do existing psychological problems (anxiety, depression, etc.) 'compound' when layered with Hashimoto ...
7
votes
2answers
7k views

Why do guys develop “abs” more easily than girls?

Is there something different in the muscle structure for males vs. females? Or does it have to do with hormones?
4
votes
1answer
1k views

Does taking melatonin cause a reduction in the amount of melatonin the brain produces?

I take melatonin fairly frequently, but I have noticed that it does not work as well as it once did. I am wondering if by taking melatonin, the brain reduces its natural production of melatonin.
8
votes
1answer
657 views

What are the benefits of high testosterone in men?

It's common to hear about products that claim to be testosterone boosters for men and vitamins that boost testosterone, but what benefits does high testosterone actually entail? For example, are ...
1
vote
0answers
51 views

menorrhagia in early hyperthyroidism

What is the pathophysiology of menustral irregularities in hyperthyroidism? Especially early menorrhagia seen in early hyperthyroidism?
3
votes
1answer
582 views

Causes of polypoid foveolar hyperplasia

Six years ago during an endoscopy, the gastroenterologist noted that he had seen a small nodule forming in my stomach. A recent endoscopy revealed 3 nodules. The biopsies showed that they were benign,...
4
votes
1answer
6k views

What is normal range of Anti TPO antiodies test?

What is normal range of Anti TPO antiodies test? My relative have undergone this test and got value 207. Her TSH is also 5.8
2
votes
0answers
98 views

What hormonal or other physiological cycles occur in men?

Physiological cycles are common in all mammals, including humans. Some of these cycles are seasonal, some circadian, some roughly monthly. Menstrual cycles in women are the most common and most ...
3
votes
0answers
142 views

Is there any harm in taking a melatonin supplement every night?

I noticed that a bottle of melatonin supplement is labelled "For Occasional Sleeplessness". The use of the word "Occasional" surprised me. Is there any harm in an adult taking a melatonin supplement ...
4
votes
2answers
807 views

Should chronic low cortisol be treated if the patient has no symptoms?

I discovered I have low cortisol levels (11,35 μg/dL) but I never had any of those symptoms listed here. My mom also has low cortisol levels. I have no HIV, no known auto-immune diseases, I believe I'...
20
votes
1answer
638 views

What are the long-term side effects of melatonin?

What are the long-term side effects of taking melatonin as an oral supplement? The couple of articles I have read are inconclusive: http://www.huffingtonpost.com/2015/03/11/what-is-melatonin-...