Questions tagged [drug-administration]

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What is "redosing"?

From the International Consensus Recommendations for the Treatment of Pediatric NMDAR Antibody Encephalitis, table 4: Maintenance (>6 mo) immune suppression: Rituximab redosing (same doses as ...
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Would slight shifting of administration times of Paxlovid impact its efficacy?

Paxlovid (nirmatrelvir/ritonavir) is an oral medication indicated for patients recently diagnosed with COVID-19 and who are at high risk of deterioration. This drug received an emergency use ...
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Does Remdesivir really go bad after reconstitution with sterile water?

I was recently looking at how long can Remdesivir be stored in its different forms. I came up across several articles provided by the FDA and Gilead Sciences and others. What caught my eye was the ...
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Muscarinic receptors in bladder

ACh contracts the wall of the bladder(by M3 receptor). How does it relax the sphincter?
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The process of drug approval; The flow from R&D, planning a clinical trial to drug approval, or other additional process

I'd like to know the process of drug approval; the flow from R&D, planning a clinical trial to drug approval, or other additional process. As far as I am aware, some documents provide too much detail ...
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Activated charcoal administered rectally?

A colleague of mine, an experienced pharmacist, told me that there used to be a product of activated charcoal called Charcodote, which could have been used either orally or rectally. I doubted this, ...
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What is the meaning of doubling of bioavailability?

I took this extract from here: https://en.wikipedia.org/wiki/Bioavailability The oral bioavailability of methyltestosterone is about 70%, and it is well-absorbed from the gastrointestinal tract.[...
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What is injected into the IV to wake a patient up from general anesthesia?

In my previous 16 surgeries in the United States, I eventually woke up from general anesthesia on my own -- it took a few hours after surgery for me to wake, but I woke up naturally in "Recovery." ...
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Are there time limits on when epidurals can be administered?

I'm not sure if this would be a hospital policy thing or a medical thing. Is it possible to get an epidural at 9cm or does it have to be administered earlier on?
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How would oral medication be given to patient in ICU that can't swallow?

How would oral medication be given to patient in ICU that can't swallow? I was told that the tablets are grind and put in water then provided through a tube. Is this true? How would the nurse know the ...
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How can Cortisol be administered in gaseous form?

How can Cortisol be administered in gaseous form (inhalation)? What carrier gas would be adequate? CO, CO2, NO (Nitric Oxide)?
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Sublingual Spray Protocol

I want to start learning about sublingual spray mechanisms. Where can I start with? Thanks in advance
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How fast and effective does an epi-pen work against a peanut allergy reaction?

Last night, I read a horror story about a baseball coach who assaulted his star player after training because she made his son look bad as the eternal number 2. He fed her peanuts while she had a nut ...
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