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Questions tagged [covid-19]

Describes the clinical disease caused by the SARS-CoV-2 virus

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What are the risk factors currently thought important for disease severity in COVID-19?

I have heard of from reading numerous journal articles, and newspaper/TV reports: age > 70 age < 5 obesity smoker cigarettes or pot male blood group not group O poor socio economic status crowded ...
Graham Chiu's user avatar
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Can the capacity for COVID-19 tests be amplified by testing multiple samples mixed together and testing each only if positive?

If I understand it right, the following steps are to be taken into account: Taking the sample: for the proposed method more samples would have to be taken. Transporting the sample: more samples ...
Philipp Wettmann's user avatar
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3 answers
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Are countries with lower life expectancy expected to have lower death rates due to Coronavirus?

Coronavirus death rates are higher for people in the range of 80+ (14,8%) and 70-79 years old (3,6%). However, there are countries, specially in Africa, where life expectancies are in the 50-60 and 60-...
Pablo's user avatar
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Where to find a database containing COVID-19 information?

Is there any global database that enables the stochastic analysis of questions such as age distribution of fatalities, etc? A Google search produced only a WHO article database: https://www.who.int/...
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What are the websites providing medical articles?

I'm new here and I'm not sure if my question is off topic, however I need some resources about medical articles concerning the effect of covid on health employees. I found a website called sci-hub but ...
Slim's user avatar
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What are some mRNA vaccines, other than COVID vaccines, that are widely used?

From what I've read, COVID vaccines belong to mRNA vaccines category. I read in the above article that mRNA vaccines act in a different way than traditional vaccines. [..]Traditional vaccines ...
Marinos An's user avatar
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What would count as definitive proof that humans can develop COVID-19 immunity?

There are currently numerous debates over whether or not people who have recovered from COVID-19 develop immunity to the disease. By the standards of the the scientific community, what kind of proof ...
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How long does COVID-19-induced anosmia/hyposmia last?

I read on https://www.entuk.org/sites/default/files/files/Loss%20of%20sense%20of%20smell%20as%20marker%20of%20COVID.pdf (mirror): There is already good evidence from South Korea, China and Italy ...
Franck Dernoncourt's user avatar
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What data is there for physicians to advise patients taking Ace Inhibitors during the COVID-19 pandemic?

Angiotensin-converting enzyme 2 (ACE2) is a membrane-bound aminopeptidase that has a vital role in the cardiovascular and immune systems4. ACE2 is involved in heart function and the development of ...
Graham Chiu's user avatar
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Would slight shifting of administration times of Paxlovid impact its efficacy?

Paxlovid (nirmatrelvir/ritonavir) is an oral medication indicated for patients recently diagnosed with COVID-19 and who are at high risk of deterioration. This drug received an emergency use ...
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Covid vaccine side effects [closed]

The Pfizer Covid vaccine caused allergic reactions. For patients that are deemed to be at an increased risk of adverse side effects following a risk assessment (e.g. because of diabetes, heart disease)...
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Updates on mortality rate once on a ventilator with Covid-19?

CNN even in fairly recent articles keeps pointing to this (March 5) Lancet page (which is an editorial summarizing an even older study published on Feb 21) for mortality rates of Covid-19 on a ...
against very long user names's user avatar
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Will everyone get the COVID-19?

There is a Ben Shapiro tweet that says: For a variety of reasons, many Americans seem to think that "flattening the curve" means that fewer Americans will get covid-19 total. This is inaccurate....
Amit Erandole's user avatar
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Does the SARS-CoV-2 (Novel Coronavirus) live longer in a fridge or freezer?

I've read the virus lives longer on metal / plastic surfaces about three days. When I go grocery shopping I rotate dry goods and canned goods such that the virus on the outside would be dead when I ...
WinEunuuchs2Unix's user avatar
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1 answer
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Would symptoms differ from eating virus contaminated food versus breathing in virus?

Would symptoms differ from eating virus contaminated food versus breathing in virus? Would symptoms be a good indicator where the virus is located? The COVID-19 causes respiratory symptoms and I guess ...
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What is the point of herd immunity?

A few weeks ago the UK has been debating about herd immunity. I understand that when most people are immune to a disease, then the disease is harder to spread. However, how are they going to ...
Andrew Yu's user avatar
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Coronavirus conspiracy theory (HIV biological weapon) [closed]

There's a ridiculous conspiracy theory spreading that coronavirus is a genetically modified biological weapon gone rogue. According to one theory, the virus has traces of HIV and is designed to attack ...
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How long after COVID-like symptoms start can one still find out if what they had was COVID?

Suppose someone has COVID-like symptoms. Let's pick an arbitrary date; say they wake up coughing on February 1st, 2022, with no prior symptoms, and unknown potential exposure date. If this person is ...
Alex R's user avatar
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Did the NIH study find Moderna - Moderna gave more antibodies than Moderna-Pfizer?

An NIH study studied the efficacy of different combinations of Covid-19 vaccines in terms of the level of antibodies produced. Dr. Rob Swanda tweeted out a chart summarizing the results: So it seems ...
Keshav Srinivasan's user avatar
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1 answer
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What are the risks associated with imidazoquinoline adjuvant (used in one Covid-19 vaccine) related to development of autoimmune diseases?

Covaxin is an inactivated virus-based COVID-19 vaccine developed by Bharat Biotech. Recently, the Brazilian health regulator Anvisa raised few concerns regarding Covaxin, one of which was- use of a ...
Prem's user avatar
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What is missing for the Pfizer-BioNTech vaccine to get "regular" FDA approval?

Last year, the US FDA issued an "Emergency Use Authorization" for Pfizer-BioNTech vaccine for Covid-19. I read the wikipedia page on what that means, and it seems as though this can be ...
einpoklum's user avatar
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How fast could mRNA COVID manufacturers switch from the Wuhan strain to e.g. B.1.1.7 and why?

I understand that the time it took Modena to go from the SARS-CoV-2 sequence to shipping doses for clinical trial was 44 days: https://www.modernatx.com/modernas-work-potential-vaccine-against-covid-...
Kaitlin Duck Sherwood's user avatar
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Can this method of immunization for horses serve as a COVID-19 vaccine for humans?

A group of scientist developed Equine polyclonal antibodies (EpAbs) obtained after immunization of horses with the receptor-binding domain of the SARS-CoV-2 viral Spike glycoprotein. https://ri....
Dare to ask-I dnt mind punishm's user avatar
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1 answer
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Would it make sense to use aspirin as a prophylactic against covid-related blood clotting?

Autopsies indicate blood clots are lethal in COVID-19. So what Is Known About COVID-19 and Abnormal Blood Clotting? I was trying to think of something that might cut down on deaths from covid-19, ...
Andre Duval's user avatar
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1 answer
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What is the rationale behind using Il-6 inhibitors to treat COVID-19 patients?

According to the Infectious Disease Society of America (IDSA), one of the possible treatment options for COVID-19 patients is il-6 inhibitors (tocilizumab, sarilumab). What is the rationale behind ...
D.Tan's user avatar
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For how long does the legal requirement to report deaths after COVID-19 vaccination to VAERS last?

The US Health and Human Services VAERS FAQ for COVID-19 says (emphasis in original): What adverse events should healthcare providers report to VAERS after COVID-19 vaccination? [...] Healthcare ...
Scott McPeak's user avatar
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132 views

Do any studies on 'Long COVID' compare to a control group?

This study, which is citied in a Harvard Health article on Long COVID, shows that ~55% of people suffered fatigue 6 weeks after having COVID-19: But it doesn't compare against the prevalence of '...
stevec's user avatar
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What are the most common ways that COVID kills?

Looking at the death counts for 2020 published on the CDC's website, total deaths "involving COVID-19" were 375,581, but total deaths "involving COVID-19 and pneumonia" were only ...
Jonah's user avatar
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How sophisticated were efforts to track the spread of past pandemics for public information?

I am currently inquiring into the COVID Tracking Project for a first-year university course. I would like to give some historical context, i.e. past attempts at pandemic tracking. Searching the web ...
Micah's user avatar
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What is the difference between medical grade and non-medical grade disposable masks?

One can buy a disposable product which appears identical to medical grade disposable surgical masks, but is not. The package or item description typically includes a clear indication that it is not ...
Anthony X's user avatar
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Does prior COVID infection increase or decrease mortality on COVID reinfection?

One recent large scale study found that a prior COVID infection doubles your risk of dying when you later catch a subsequent COVID infection. This study followed 5 million people in the Veterans ...
Ash90's user avatar
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0 answers
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Do mutations occur while growing virus for preparing inactivated viral vaccine?

The development of mutations in virus is reported to happen during replication, especially for an mRNA type virus like SARS-COV-2 Viruses that encode their genome in RNA, such as SARS-CoV-2, HIV and ...
karthikeyan's user avatar
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What cells and how many of those are infected and destroyed as a result of COVID-19 vaccine?

My understanding is that cells modified by COVID-19 vaccines will eventually get killed by immune system. Do we know what cells are usually targeted by vaccines and how many of those get killed as a ...
Tofig Hasanov's user avatar
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0 answers
88 views

Is there any data on herbal supplements interfering with the efficacy of vaccination?

Here's an excerpt from a paper published in "Journal of Inflammation Research" by Dove Press for a popular and controversial herbal supplement from India: Coronil effectively inhibited the ...
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0 answers
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How are two-dose vaccine schedules developed?

How are vaccination schedules determined for multi-dose vaccines? That is, are several different schedules tested in an early-phase trial? Or do the developers of a vaccine choose a schedule (based on ...
Daniel M.'s user avatar
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Why does the Pfizer vaccine need storage at -70C but Moderna's only needs -20C, when they are both mRNA vaccines?

It's been widely reported in the press that Pfizer's vaccine needs storage at -70C but Moderna's only needs -20C. Why is this so, when they are both mRNA vaccines? There's actually a looong article in ...
against very long user names's user avatar
4 votes
0 answers
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Does being outdoors but in close proximity to someone make a difference in Covid-19 transmission?

In a recent news article I've read that Outdoor haircuts were allowed in California from Tuesday, under new rules announced by the mayor, but indoor salons remain shut. Is this kind of rule/...
against very long user names's user avatar
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0 answers
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Why does the world-wide COVID-19 death rate appear to be constant?

Total confirmed COVID-19 deaths per million people One would normally expect the total deaths to be growing exponentially (going viral) or to be damping down and approaching a constant (zero new ...
Ray Butterworth's user avatar
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0 answers
187 views

What data is available on hospitalization rates of COVID-19 patients by risk factor? [closed]

What data and analysis is available on hospitalization rates of COVID-19 patients by age and pre-existing condition? Estimates of death rates have been communicated, but I have found no similar ...
Croad Langshan's user avatar
4 votes
0 answers
226 views

What is a sophisticated estimate of the 2019-nCoV fatality rate?

I've read through this Q&A: Is the mortality rate of 2019-nCoV 41%? My understanding from reading that Q&A is that in the early phase of an outbreak, there are two naive ways to estimate ...
Mick's user avatar
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1 answer
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Why are government decisions being led by the number of COVID CASES (as opposed to actual deaths)? [closed]

Since the early days of COVID-19, when very little information was available regarding this new virus, we now have an abundance of data. Data such as: Cases recorded, per nation, per time period ...
Chris Melville's user avatar
3 votes
2 answers
170 views

Is AstraZeneca having better safety record than Pfizer or Moderna?

Recently, AstraZeneca vaccine got some bad press for few cases of blood clouts as side effect leading some countries to even suspend its use for people younger than 56 (see here). I am not a medical ...
1muflon1's user avatar
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2 answers
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How can Stockholm be close to herd immunity without having overwhelmed the healthcare system?

According to several sources, models estimate 20% of people in Stockholm are already immune to COVID-19 (2014-04-22). However, German virologists estimate (2020-04-19) that to reach herd immunity in ...
gerrit's user avatar
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2 answers
126 views

Does wearing gloves help against being infected with COVID-19?

Walking around town I see quite a few people wearing gloves in addition to a mask. But is this actually useful? COVID-19 does not transmit via the skin, so you don't need to protect your hands per se. ...
JonathanReez's user avatar
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3 votes
3 answers
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How can immunity be developed without a vaccine? (re Merkel's speech)

Recently, German Chancellor Angela Merkel gave a speech about the importance of slowing down Covid-19. Among her remarks were The most important thing, the chancellor said, is to slow down the ...
Reinstate Monica's user avatar
3 votes
3 answers
164 views

Is outside food really safe to eat during COVID-19 outbreak?

There are 2 contradicting messages out there that mandate this question: "It may be possible that a person can get COVID-19 by touching a surface or object that has the virus on it and then touching ...
2020's user avatar
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3 votes
4 answers
275 views

Why are Novel Coronavirus anitbody tests disparaged?

The Novel Coronavirus antibody test has been around since February 2020 when it was invented at a Chinese University. It can measure both IgM to show infection in progress and IgG to indicate full ...
WinEunuuchs2Unix's user avatar
3 votes
2 answers
201 views

Could an infinitesimal amount of Covid-19 be used to trigger immune response?

Could one be injected with an infinitesimal amount of Covid-19 viral particles, in a way that it would trigger an immune response long enough before the virus overran the body? Could it be injected ...
John Pankowicz's user avatar
3 votes
1 answer
82 views

Does a shorter COVID-19 vaccination interval increase efficacy of booster vaccines?

In performing research on COVID-19 vaccines, I came across this WebMD article regarding the efficacy of bivalent boosters against recent COVID-19 variants. The article includes a quote from Dr. Hana ...
End Antisemitic Hate's user avatar
3 votes
1 answer
103 views

Is the code from the mRNA vaccine executed by the cells as a one-off? [closed]

Is the code from the mRNA vaccine executed by the cell that has taken it up as a one-off or does the cell produce the spike proteins endlessly (like a programming loop) until the cell is killed by the ...
Lukasz Korzybski's user avatar

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