Questions tagged [covid-19]

Describes the clinical disease caused by the SARS-CoV-2 virus

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Do vaccinated people not have zero risk of mortality by Covid 19?

This video by Vox says people who are vaccinated have zero risk of mortality by Covid 19. But NDTV reports (at 00:21 and again at 07:53 in the video) that even fully vaccinated 8 frontline medical ...
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Is SM-102 a safe ingredient in the Moderna vaccine, despite these safety warnings?

I recently saw a post online which called into question the safety of the Moderna vaccine through an interesting argument. One of the ingredients in the Moderna COVID-19 vaccine is the ionizable amino ...
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What exactly is the difference between Sputnik V lite and Astrazeneca vaccine?

As far as I know, both Astrazeneca and Sputnik V lite are Vector vaccines using an Adeno virus as a vehicle for the DNA of the spike protein of Covid-19. But Astrazeneca requires two vaccine shots ...
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Why do some vaccines cause flu-like symptoms? Why does this seem to be more severe in mRNA vaccines?

Flu like symptoms are noted as possible reactions on nearly every vaccine I've had since adolescence, but I've never actually seen these symptoms in myself or anyone, until now? I don't doubt that ...
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Antibody test after vaccination with BBIBP-CorV

After vaccination with BBIBP-CorV (inactivated) which of the following tests can be taken to determine if the vaccine produced an immune response: IgM for N protein IgG for N protein IgG for S ...
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what causes hypoxia in Covid19?

What is known right now about the causes of hypoxia in Covid19 infection ? Does it comes from thrombosis formation in lung vessels ? And/or because of damage of lung alveoli by viral replication ? Or ...
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Were thrombocyte counts or bleeding events monitored at all during ChAdOx1 (AZD1222) clinical trials?

Maybe I'm just missing something, but on a quick look, I find it a bit strange that since issues with thrombocyte (platelet) counts in adenovirus-vectored therapeutics have (1) been known for about ...
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Is the decrease in vaccine uptake in the US for two weeks in a row in line with some models' expectation?

According to Reuters news of May 3, vaccinations have also fallen in the US for two weeks in a row. Nationally, deaths from COVID-19 fell 3% to 4,819 in the week ended May 2, the fewest deaths in a ...
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Would it be okay to have the Astrazeneca vaccine if I had dengue hemorrhagic fever as a child? [closed]

Although it happened more than two decades ago, I still remember being very ill, vomiting so much blood at one point. I was given an IV drip and had to stay in hospital for a while. Would having had ...
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What is the historical or scientific basis for concern about COVID vaccines and pregnant women and their babies?

There's a lot of talk about whether COVID vaccines are safe for pregnant women and their fetuses. Current guidelines, while mentioning that there's little data, suggest that they are safe. However, I'...
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When speaking of vaccine efficacy (for COVID-19, or other), is immune response or efficacy really being measured? [duplicate]

I've been performing many web searches using combinations of the words "vaccine", "vaccination", "COVID-19", "coronavirus", "efficacy", and "...
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Covid-19 and Original Antigenic Sin

My understanding of original antigenic sin, which I admit is minimal, is that with some pathogens, your immune system gets too focused on one variant and thus is wholly unprepared to deal with a ...
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Will there be any error in the result if the sample taken for COVID-19 RT PCR test is kept for days before performing the test?

What would be the impact of keeping the sample (nose swab) for 5 days before performing RT-PCR on it? If no, then is there a particular way of storing the sample. Is there any standard set by the ...
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Has the initially reported rate of anaphylaxis following the Pfizer Covid-19 vaccine been sustained in later data?

A CDC/MMWR study that made the news back in January found that: The CDC said there were 21 cases of anaphylaxis — a severe and life-threatening allergic reaction that occurs rarely after vaccination —...
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Is there any data on herbal supplements interfering with the efficacy of vaccination?

Here's an excerpt from a paper published in "Journal of Inflammation Research" by Dove Press for a popular and controversial herbal supplement from India: Coronil effectively inhibited the ...
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what does 95% effectivenes mean for vaccines (covid) [duplicate]

Often we see in news they say AstraZeneca is 95% effective, while Chinese vaccine is 50%. I have question how to interpret these numbers. Does this mean that if you get vaccinated with AstraZeneca ...
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What are the "theoretical risks" of COVID vaccines in mothers

In Germany, there is no official endorsement of COVID mRNA vaccines for pregnant women and nursing mothers due to a lack of study data. Still, professional societies generally recommend considering ...
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Can Weightlessness help cleaning lungs from Microorganism in Covid-19 patients? [closed]

We know that cleaning lungs from Microorganisms in Covid-19 patients is hard. But In Weightlessness materials easily move around. So could Artificial Weightlessness help doctors for safer and more ...
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Why have so few people received a second dose of the vaccine COVID-19 in India?

From https://www.google.com/search?q=india+covid+cases&oq=india+covid+cases: Why have so few people received a second dose of the vaccine COVID-19 in India? I've searched for "india second ...
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How does the thrombosis risk of COVID compare to that of the vaccines?

There was some news, possibly based on this paper, that the risk of thrombosis caused by COVID-19 is supposedly 10 times higher than that of "vaccination". To me this conclusion seems flawed ...
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Why do the COVID vaccines not cause the body's immune system to over-react?

It was my understanding that the reason why some people suffered serious effects from a COVID19 infection is that their immune system over-reacted to the disease, causing havoc all over. Why doesn't ...
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Which covid-19 vaccines have suspected cases of thrombosis?

As far as I know, Astrazeneca, Moderna, Pfizer and Johnson & Johnson have suspected cases of thrombosis. U.S. Recommends Pausing Use Of Johnson & Johnson Vaccine Over Blood Clot Concerns ...
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COVID-19 mutation nomenclature

Consider: Source: Where Do COVID Vaccines Stand Against the Variants? The nomenclature seems to follow a hierarchical pattern. What does the first letter and the subsequent numbers indicate? Location ...
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Did those who lose smell due to covid regain it after all?

We know people for example can lose taste or smell due to covid, some have this even for months, but is there data if people eventually do get this senses back or not?
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Are coronavirus-like spikes only seen in viruses?

Are there any natural proteins or cells (or anything) made by the human body with spikes like those of Covid-19? I know that there have been no serious side effects reported from the Covid-19 vaccine, ...
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How is the decision for recommending a vaccine reached

There is an ongoing discussion about the use of the AstraZeneca covid-19 vaccine (Vaxzevria) in Europe. Some countries like Germany restrict the use of this vaccine, some - like Austria - do not. How ...
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How accurate is the individual number covid-19 variant cases in each state?

How accurate is the individual number of covid-19 variant cases in each state? US COVID-19 Cases Caused by Variants I am trying to estimate the risk of being exposed to the one B.1.351 variant where ...
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Why does San Marino have the most total deaths per million and a CFR of 1.8%?

Is there any way that one could explain the following? San Marino has the most total deaths per million and a CFR of 1.8%. Bosnia and Herzegovina is currently 8th for the most total deaths per million ...
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What is missing for the Pfizer-BioNTech vaccine to get "regular" FDA approval?

Last year, the US FDA issued an "Emergency Use Authorization" for Pfizer-BioNTech vaccine for Covid-19. I read the wikipedia page on what that means, and it seems as though this can be ...
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Covid-19: what's (usually) the probability of getting a negative PCR result conditioned on getting a positive antigen test result first?

It's been pointed out to me that most studies comparing antigen with PCR tests either consider these as independent tests carried out over the whole sample (and report concordance/discordance that way,...
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Is the number of deaths (1,913) amongst people who received a COVID-19 vaccine higher than amongst people who didn't receive a COVID-19 vaccine?

The Centers for Disease Control and Prevention states: Over 109 million doses of COVID-19 vaccines were administered in the United States from December 14, 2020, through March 15, 2021. During this ...
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Why should/shouldn't one fear the long-term health effects of the Covid vaccines?

I'm aware that some people don't want to take a vaccine for Covid-19, and in fact some countries have suspended rollout of some vaccines due to some young people getting blood clots. Also some people ...
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Is there any live tracker following the adverse events for COVID-19 vaccines?

I have seen a few trackers for the vaccination campaign: https://www.bloomberg.com/graphics/covid-vaccine-tracker-global-distribution/ https://ourworldindata.org/covid-vaccinations https://www....
Franck Dernoncourt's user avatar
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If COVID-19 isn't spread through even food, why is it recommended to disinfect common objects?

Currently, researchers say that there is no evidence of COVID-19 spreading through food: "The risk of getting COVID-19 from food you cook yourself or from handling and consuming food from ...
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Antigen vs PCR test

In the Czech Republic there is now mandatory testing for factory employees. Anecdotally I am now being told by people I am acquainted with, who run medium sized firms here, that their employees are ...
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Can vaccines cause side effects that the virus itself will not cause? [closed]

The COVID vaccines have reignited the discussion about vaccines’ potential side effects. While we all know these are extremely rare, I would like to understand how they are even possible at all. A ...
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Are side effects of corona virus vaccines no worse than virus symptoms?

In my country there is a general fear for side effects of the Pfizer and Astrazeneca vaccines, also due to some deaths among people having taken the vaccine. I reason that since the vaccines replicate ...
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Is there a single documented case of severe COVID-19 in a patient having fully recovered from COVID-19?

Is there a single documented case of severe COVID-19 (reinfection) in a patient having fully recovered from COVID-19? For the purposes of this question, I'm excluding people with an immune disease, ...
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What effect does social distancing have on the contagiousness and lethality of virus spread?

There are various degrees of 'lockdown'. From poorly worn masks and poor material choices, to people being confined to their homes for long periods of time. It is safe to assume that practical ...
Frank's user avatar
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What's the difference between rt-PCR COVID-19 test using different lengths of nose swab?

I read: Our nose swabs only enter the nose ½ inch, not all the way up the nostril, ensuring no pain or damage. A few months ago, I had a COVID-19 test with a nose swabs that looked like ~5cm. What's ...
Franck Dernoncourt's user avatar
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Is the Cytokine Storm the root cause of fatality mechanisms of COVID-19?

A cytokine storm means a cell pathway has been turned on, leading to the production of a number of biological mediators (which are kind of like signal transmitters) that cause changes to the body and ...
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What is the minimum air temperature that can kill SARS-CoV-2 instantaneously?

I found this paper that talked about an air filtration system that heats up air to 200°C that kills SARS-CoV-2 in a single pass. But they seem to not be so sure of how hot it should actually be. I've ...
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Covid19 Rapid serological tests and Vaccine

Let's say that once I'm vaccinated I try the rapid serological test and the result is negative. My question is: let's admit that the reliability of the test is 100%; does it mean that the vaccine didn'...
Avles Edivad's user avatar
2 votes
2 answers
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Why wouldn't the Pfizer, Moderna, AstraZeneca, and Johnson & Johnson vaccines be equally effective?

Based on what I have read, the Pfizer, Moderna, AstraZeneca, and Johnson & Johnson COVID-19 vaccines all work by training the immune system to recognize the spike protein on the surface of the ...
pacoverflow's user avatar
4 votes
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How are two-dose vaccine schedules developed?

How are vaccination schedules determined for multi-dose vaccines? That is, are several different schedules tested in an early-phase trial? Or do the developers of a vaccine choose a schedule (based on ...
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Are Covishield and AstraZeneca AZD1222 the same?

Some sources simply equate the two. On the other hand, Covishield seems to be undergoing its own clinical trials. The statement by the Indian authorities calls it “Recombinant Chimpanzee Adenovirus ...
Roman Odaisky's user avatar
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What protection does T-cell immunity confer for Covid?

This preprint, which was just released today, says that while some of the Covid-19 variants evade antibody immunity, they do not evade T-cell immunity. It says that this is true both of T-cell ...
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UPDATED Why is the new viral vector vaccine unable to modify human DNA?

UPDATE: Adding additional information after digging around. First, I am not a medical professional. I found this article studying the rates of DNA integration via adenovirus vectors in mice, ...
dant's user avatar
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Do partial lockdown/social-distancing measures lead to more contagious and more deadly (Covid) virus mutations? [closed]

Reduction in social contact, without full restriction of social contact, creates an environment where the 'success' of a virus depends more on how infectious it is and less on how good it is at ...
Frank's user avatar
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Is there a simple way to quantify viral content beeing exhaled by a person potentially independent of the specific virus type?

As far as I have understood it, persons who have contacted virusses (that are to a substantial part transmitted through the air, such as covid-19) tend to be only or most strong infectuous during a ...
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