Questions tagged [clinical-study]

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1answer
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Definition of “prospective birth cohort study”

From a news article: “Prospective birth cohort studies suggest that childhood infections are associated with increased risk of schizophrenia in adulthood and with abnormal neurodevelopment in ...
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Meaning of “shared familial confounding” in a study

From a news report: Using population-based, longitudinal cohort study data from Sweden, researchers examined the relationship of infection during childhood with IQ and adult nonaffective psychosis....
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How are participants in a clinical study of a new medication selected and monitored?

I don't have any background in medicine, but I'm interested. How are participants in a clinical study of a new medication selected and monitored? Do they make an announcement calling for volunteers? ...
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Do side effects spoil blind studies?

One group is given a newly developed medication X, and the other group placebo. If X has noticeable side effects, like extra sleepiness, change in appetite, tremors, etc, wouldn't the participates in ...
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1answer
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What clinical studies demonstrated that CelGro improves tissue in-growth and repair for the rotator cuff tendon injuries?

I read on https://stockhead.com.au/health/orthocell-wins-patent-for-tech-that-can-grow-you-a-new-body/ (mirror) CelGro has been shown to improve tissue in-growth and repair in clinical studies using ...
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1answer
93 views

Long term side effects of Xolair

I get 300mg of Xolair injected twice a month (every 2 weeks). I was wondering if there are any studies showing long term side effects of this medicine that are not published by the manufacturers of ...
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1answer
266 views

What does “Primary Purpose: Treatment” mean in a clinical study?

At clinicaltrials.gov you can look up studies to learn more about them. On one such study, I saw this block of text: Study Type: Interventional Study Design: Allocation: Randomized ...
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Do drugs that increase (or don't decrease) mortality during clinical studies still get approved and if so - why?

From reading about clinical studies on various chronic diseases, I get a sense that increasing lifespan is rarely the primary objective of these studies, and instead they focus on surrogate markers, ...
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1answer
30 views

For a purpose of a clinical study, what is considered to be a cardiovascular death?

In the FOURIER study (to lower cholesterol with PCSK9), there is a significant reduction in different types of cardiovascular events (MI and Stroke) in the treatment group and yet the total ...
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1answer
111 views

Are there scientific studies that support the daily usage of xylitol to prevent oral problems?

Since more than 2 years I'm consuming birch sugar (xylitol) instead of sugar for basically everything and I try to avoid any product which contains sugar. Note that I wasn't consuming too many things ...
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Are there any examples of successful multi-decade prevention interventions with pharmaceuticals?

With many tests able to detect various physical abnormalities, even before symptoms develop (if ever), modern treatments may require individuals to take medications for decades. Are there any examples ...
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1answer
218 views

Multiple Sclerosis and Chemotherapy

I caught part of a cable television program but I ended up falling asleep but it seemed interesting (I was just exhausted). Basically it talked about chemotherapy being a so-far proven treatment for ...
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Good Resoures for Learning/Studying GCP

Are there any widely accepted resources out there for studying/learning good clinical practices in the U.S. outside of the actual FDA webpage for the matter? Something an entry-level clinical ...
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1answer
57 views

Are these studies about red algae reducing cold virus by 92% believable? [duplicate]

I was using this spray meant to hasten recovery from the common cold. A study [1], sponsored by the pharmaceutical company that produces the spray, stated it reduced virus by 92% (this value only ...
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1answer
88 views

Is this study stating red algae reduces cold virus by 92% believable?

I was using this spray meant to hasten recovery from the common cold. This study, sponsored by the pharmaceutical company that produces the spray, stated it reduced virus by 92%, and so shortens the ...
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2k views

Does melatonin have an effect on the treatment of type 1 diabetes?

Type 1 Diabetes is a chronic disease characterized by the body's inability to regulate blood sugar due to a disabled pancreas' not producing insulin. People with diabetes regulate their own blood ...
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1answer
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Are there current studies about long term development of WPW in children?

Our daughter was diagnosed with Wolff–Parkinson–White syndrome (WPW) at zero weeks age in April 2014. I found a very interesting study from 1990 that talks about the long term development of WPW. It ...

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