Questions tagged [cancer]

The disease caused by an uncontrolled division of abnormal cells in a part of the body or when describing a malignant growth or tumor resulting from the division of abnormal cells.

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16 views

Could eumelanin taken orally darken skin? [closed]

Darker skin is desirable to some individuals for a variety of reasons: UV tolerance, reducing skin cancer risk, aesthetics. While a number of other approaches exist, mostly to which solar exposure ...
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How does a Mohs surgeon decide whether to follow Langer's lines for a forehead Mohs surgery?

I see some Mohs surgeons following Langer's lines {1}: while some decide to be perpendicular to Langer's lines, e.g. https://youtu.be/pulxPm4PmkQ: How does a Mohs surgeon decide whether to follow ...
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Can cancer incidence rates, calculated from the general population, be used in primary care?

I calculated incidence rates (IR) for colorectal cancer using an age-period-cohort model. Is it useful for GPs to use such age, gender and anatomical sub-site specific IRs as a baseline risk, during ...
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Why are the surgical margins for invasive ductal carcinoma less than the margins required for invasive ductal carcinoma in situ?

Per the NCCN guidelines version 4.2020 (which is unfortunately pay-walled), for invasive ductal carcinoma (IDC), the recommended margins are no tumor on ink, while isolated ductal carcinoma in situ (...
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What is the success rate of topical imiquimod 5% cream to treat infiltrative basal cell carcinoma (BCC)?

What is the success rate of topical imiquimod 5% cream (US brand: Aldara) to treat infiltrative basal cell carcinoma (BCC)? So far I've only found some case study {1} and some study on using topical ...
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How effective is topical fluorouracil to treat facial superficial basal cell carcinoma (BCC) after Imiquimod 5% cream failed to treat it?

Both Imiquimod 5% cream and topical 5-Fluorouracil (5-FU) have been used to treat basal cell carcinoma (BCC) with a fair amount of success (~60 to 90% success rate at 5-year follow-up) {1}. Imiquimod ...
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Why is Imiquimod 5% cream used to treat a superficial basal cell carcinoma less effective on lower limbs than the rest of the body?

I read on https://bpac.org.nz/2017/skin-cancer.aspx (mirror): It is less effective when used on lower limbs and generally impractical for the posterior trunk due to inaccessibility. Why is Imiquimod ...
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Should Imiquimod 5% cream be applied 1 cm beyond the target tumor when treating a facial basal cell carcinoma, and if so, why?

I read on https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/20723s016lbl.pdf (mirror): 364 patients with primary superficial basal cell carcinoma (sBCC) were treated with Aldara Cream or ...
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Does being underweight have an influence on cancer risk?

This occurred to me reading Lifetime cancer risks for for people with healthy lifestyles? When talking about cancer in regards to body weight, it's usually about obesity. But does being underweight (...
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How is Allred score found in an IHC breast tissue image?

In breast cancer immunohistochemistry (IHC), usually breast tissues are stained with ER/PR (Estrogen/Progesterone) stains so that ER/PR receptors (if present) show up. Allred score is a way of finding ...
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Chronic Myeloid Leukemia blast percentage

I'm trying to understand the oncogenesis of CML. I have a question about CFC cells and blast cells. Are those the same? I know that in the chronic phase of CML there is a blast percentage of 1-10% of ...
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How carcinogenic are neoprene coated dumbbells?

I have read in many places online that neoprene coated dumbbells may cause cancer. Just how carcinogenic are they? Would normal use of said dumbbells (say less than one hour per day) be of any risk? ...
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103 views

Teeth cancer in Humans [closed]

https://en.wikipedia.org/wiki/Cancer https://en.wikipedia.org/wiki/Human_tooth https://www.google.com/search?q=teeth&oq=teeth&aqs=chrome..69i57j0l3j69i60.10521j0j7&client=ms-android-lava&...
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What specific factors give rise to the mortality rates depending on cancer type?

In my experience it is commonly communicated that certain types of cancer have a higher rate of mortality than others. For instance1, pancreatic cancer has a very poor prognosis while the prognosis ...
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Why does metastatic bone cancer present as back pain that is “worse at night”?

One "classic" presentation of metastatic bone cancer is back pain that "tends to be worse at night and may get better with movement" - American Cancer Society. Googling "back pain worse at night from ...
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What does the drug manufacturer mean by “stopping blood vessels growing in the cancer”?

From the leaflet of a drug called Revlimid(R) (active ingredient: lenalidomide): How Revlimid works Revlimid works by affecting the body’s immune system and directly attacking the cancer. It works in ...
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Studies On The Affect Of Immunotherapy On Larynx Surgeries

I've been searching online for a study regarding the affect of immunotherapy on the necessity for an affected individual diagnosed with laryngeal cancer to require larynx surgery, to no avail. Could ...
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Why aren't purine analogs effective in non-hematological malignancies?

FDA has approved many purine analogs e.g. thioguanine, cladribine, pentostatin, mercaptopurine for various forms of leukemia and/or lymphoma, but none for non-hematological malignancies. What makes ...
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Do these diagrams have an official name (treatment plan, treatment schedule, protocol)

I am doing research on treatment plans and protocols in order to design software to minimize error when indicating medicine, procedures, exams, etc. We also want to monitor treatment and somehow ...
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How long do trials for “cancer vaccines” usually take?

2 years ago we've heard about a "cancer vaccine" be ready to be tested in humans. Cancer vaccine trial . By that time a person I know (with no experience whatsoever in Medicine) told me he &...
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How hazardous is a cellular base station-antenna to our health?

A telephone company is installing a cell tower (cellular base station-antenna) 40 meters from my house (right in front of my house). The first thing I am concerning about is its effect to our health. ...
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What are survival rates of male patients in stage IV throat cancer that has metastasised to the lower pallet?

The patient is receiving a combination of radiotherapy and chemotherapy. The surgery to remove the cancerous throat tissue was not entirely successful as the surgeon discovered that the cancer had ...
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How safe is low frequency radiation in I.T. edge cases? (5G, etc)

Closely Related: 5G Radiation Dangerous? Being inundated with all kinds of 5G health statements, (for & against), I noticed a weird trend - the absence of cumulative radiation studies. Question: ...
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Real dangers of CT Scan made only once at age of 31

I have zero medical knowledge (only the basic "common" ones) and I would like some opinions from you experts about CT Scan. My girlfriend had a CT scan done some days ago, and since then she's ...
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What is the meaning of T2 Nx Mx in histopathological examination?

My dad's histopathological examination (HPE) of his rectal adenocarcinoma says T2 Nx Mx. Hence, it means that the lymph nodes were not assessed. However, as per my understanding, when the rectum/colon ...
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Immune system recovery from chemotherapy

I'd like to know if your immune system will recover from chemotherapy, say, after x years, or will your immune system forever be weakened/compromised from chemotherapy?
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Is there any health risk in cellular phones?

Cellular phones are taking ever increasing part in our lives, and I keep hearing people saying they are harmful to our health. Are there any scientific researches so far proving or disproving those ...
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CT scans and cancer risk

I've had maybe 5 or 6 CT scans over the course of my life, and I'm only 27. What risk do those CTs present to someone like me?
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Is biopsy still required for cancer diagnosis given that advanced medical imaging is now available?

For cancer diagnosis, there is biopsy, an invasive technique. However, PET CT, SPECT CT, MRI are non-invasive. Do oncologists still require the use of biopsy to ascertain type of cancer, i.e., to ...
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Why does following a fiber-rich diet help reduce the odds of getting cancer?

Following a fiber-rich diet seems to help reduce the odds of getting cancer, according to some scientific studies. Why would fibers help preventing cancers? WebMD indicates an indirect effect: fiber-...
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Meaning of “I” in a table in a study poster

From a poster to a study: I don't understand the meaning of "I" used in several fields of this table. What could it mean? I've read the abstract of the study but still cannot get it. The ...
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Meaning of “the benchmark for median survival”

From the Background section of a clinical trial poster: Good performance, unresectable stage III non-small cell lung cancer (NSCLC) patients should receive standard-of-care treatment, i.e. Concurrent ...
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Meaning of “(ref)” in a table describing the characteristics of patients taking part in a cancer study

From a poster describing a study in cancer patients. This is from a table in the poster, which describes the characteristics of the patients (Age groups, Sex ect.) You can see what percentage of the ...
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Who are “good performance patients”?

I'm translating a study poster and came across the following excerpt: Good performance, unresectable stage III non-small cell lung cancer (NSCLC) patients should receive standard-of-care treatment, i....
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Why is the Virchow node involved in Gastric Adeonocarcinoma?

The lymph node drainage of the stomach is via the pyloric and related lymph nodes. Either way, the supraclavicular node (Virchow's node) is not the first lymph node that drains the Stomach. According ...
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Can chronic prostatitis be a risk factor of prostate cancer for patients?

I have learned from the internet that chronic prostatitis can last for a long time without cure, can this disease arise prostate cancer to patients?
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How to detect colon cancer?

How can a person get to know that he/she is suffering from colon cancer? What are the symptoms, and how long does it take for them to appear?
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Eating egg shells: advantages v.s. disadvantages?

I am an engineer and a scientist, but not in the field of medicine or health. Partial answers/comments are welcome. Some of my family members start eating egg shells for the sake of obtaining ...
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About Fuzzy Logic Based Expert System impact factor in typical cancer detection

I have this part of paper (its PDF file) : Fuzzy Logic Based Expert System for Detecting Colorectal Cancer So i like to know the medical doctors view point about the emboldened (bolded) sentences ...
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Is a hyperventilation+hypoventilation breathing exercise (Wim Hof Method) more likely to prevent or promote cancer?

Apart from exposure to cold, the core element of the Wim Hof Method is a breathing technique, which alternates between hyperventilation and hypoventilation (apparently similar to Tummo meditation). It ...
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Diameters of vessels metastases spread through

As I know, one of the way tumor may metastasis is, forced by hypoxia, creating new vessels near it, connecting them to the main circulatory system and then spread cells through the blood. If ...
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Do carrots cure cancer?

**Do carrots cure cancer? ** There’s a lot of unsubstantiated information online about carrots and cancer. There are even a few books. What does science actually say about how carrots affect cancer ...
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Where can I find the total number of people living with or beyond cancer for the UK and globally, as up to date as possible (<2020)?

I'm trying to work out the total prevalence of cancer (all types) in the UK and globally, defined as someone who is alive and has had a cancer diagnosis at some point in their lives. I'm really ...
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How many people are affected by hepatocellular carcinoma (HCC) worldwide today?

Does anybody know how I can learn how many people are affected by hepatocellular carcinoma (HCC) worldwide today? I need this information for a research study; I tried to search on Google but I only ...
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Why haven’t other research groups invested into antineoplastons when it comes to cancer treatment?

I recently stumbled upon antineoplastons which is a family of drugs based on chemical natural products prevalent in human blood and urine. I have only been able to find one person administering ...
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Do Tamoxifen and other similar SERMs reduce chest fat chronically or permanently?

I am sorry if it mistaken (please comment or suggest an edit to fix) but by chronically I mean as long as the molecule is administered and effective and by permanently I mean after the molecule was ...
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What is the relationship between cancer and sugar? [closed]

I was watching "The Magic Pill" documentary series on Netflix. And, a woman indicated that she completely cured a fairly aggressive breast cancer by eliminating just about all sugars and most ...
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Cancer treatment through regulation of myeloid-derived suppressor cells

There are many ongoing clinical trials that leverage the power of the immune system to recognize tumor cells such as CD47 and PDL1/PD1, and even engineered T cells! I ran across an immune cell type ...
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Why is there is no screening for Ovarian Cancer?

From what I have read it is not considered effective to screen for ovarian cancer in non-symptomatic women. Would it not be worth doing an ultra-sound scan, then if there are growths found, do a ROMA ...
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How exactly does induced Scalp Hypothermia prevent alopecia (hair loss) during chemo therapy?

Recent studies 1 of women getting chemo for early-stage breast cancer have found that at least half of the women using one of these newer devices lost less than half of their hair. 2 Scalp ...