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Questions tagged [basal-cell-carcinoma]

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Why are some areas of the face more likely to have basal cell carcinoma (BCC) recurrences than others?

BCC = basal cell carcinoma. I read on {4}: Certain clinical and pathological features of BCC are associated with an elevated risk for recurrence after treatment. Recurrent BCC may reappear months to ...
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3 votes
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What percentage of facial basal cell carcinomas (BCC) are superficial or infiltrative?

I read here (mirror): Superficial basal cell carcinoma: Approximately 10-15% of all BCCs are of this type. This is the most common pattern seen in BCCs of the shoulder. The solid (nodular) type ...
Franck Dernoncourt's user avatar
2 votes
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How accurate is reflectance confocal microscopy (RCM) to predict whether a basal cell carcinoma (BCC) is infiltrative or superficial?

Reflectance confocal microscopy (RCM) is a noninvasive imaging technique that has been used to diagnose basal cell carcinoma (BCC). How accurate is RCM to predict whether a BCC is infiltrative or ...
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What's the success rate of Imiquimod Cream 5% recommended for the treatment of facial superficial basal cell carcinoma beyond 5 years post-treatment?

I have read several studies on the success rate of Imiquimod Cream 5% for the treatment of facial superficial basal cell carcinoma, however none of them looked at beyond 5 years post-treatment. E.g. {...
Franck Dernoncourt's user avatar
1 vote
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Why may a small basal cell carcinoma (BCC) treated with radiation be much more aggressive than it appears on the surface?

I read on https://www.skincancer.org/blog/ask-the-expert-why-am-i-having-surgery-to-remove-a-small-basal-cell-carcinoma/ (mirror): In addition, a small BCC in an area previously treated with ...
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Does ingesting itraconazole pills increase the likelihood of success for a topical cream (Imiquimod/5-Fluorouracil) to treat BCC?

The 2014 phase II trial {1} indicates that oral itraconazole is beneficial for the treatment of basal cell carcinoma (BCC). Imiquimod 5% cream and topical 5-Fluorouracil (5-FU) have also been used to ...
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Why isn't Imiquimod Cream 5% recommended for the treatment of superficial basal cell carcinoma located on the face?

I read on Approval Package for Imiquimod Cream, 5% on February 25, 2010 (mirror): Reference Drug (NDA number): Aldara® (imiquimod) 5% Cream (NDA 20-723), Graceway Pharmaceuticals. Date of approval: 2/...
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How effective is topical fluorouracil to treat facial superficial basal cell carcinoma (BCC) after Imiquimod 5% cream failed to treat it?

Both Imiquimod 5% cream and topical 5-Fluorouracil (5-FU) have been used to treat basal cell carcinoma (BCC) with a fair amount of success (~60 to 90% success rate at 5-year follow-up) {1}. Imiquimod ...
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Should Imiquimod 5% cream be applied 1 cm beyond the target tumor when treating a facial basal cell carcinoma, and if so, why?

I read on https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/20723s016lbl.pdf (mirror): 364 patients with primary superficial basal cell carcinoma (sBCC) were treated with Aldara Cream or ...
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