Questions tagged [basal-cell-carcinoma]
The basal-cell-carcinoma tag has no usage guidance.
19
questions
1
vote
0
answers
25
views
What's the success rate of Imiquimod Cream 5% recommended for the treatment of facial superficial basal cell carcinoma beyond 5 years post-treatment?
I have read several studies on the success rate of Imiquimod Cream 5% for the treatment of facial superficial basal cell carcinoma, however none of them looked at beyond 5 years post-treatment. E.g. {...
- 10.1k
0
votes
0
answers
20
views
Does ingesting itraconazole pills increase the likelihood of success for a topical cream (Imiquimod/5-Fluorouracil) to treat BCC?
The 2014 phase II trial {1} indicates that oral itraconazole is beneficial for the treatment of basal cell carcinoma (BCC). Imiquimod 5% cream and topical 5-Fluorouracil (5-FU) have also been used to ...
- 10.1k
3
votes
0
answers
28
views
Why are some areas of the face more likely to have basal cell carcinoma (BCC) recurrences than others?
BCC = basal cell carcinoma.
I read on {4}:
Certain clinical and pathological features of BCC are associated with an elevated risk for recurrence after treatment. Recurrent BCC may reappear months to ...
- 10.1k
1
vote
0
answers
15
views
How accurate is reflectance confocal microscopy (RCM) to predict whether a basal cell carcinoma (BCC) is infiltrative or superficial?
Reflectance confocal microscopy (RCM) is a noninvasive imaging technique that has been used to diagnose basal cell carcinoma (BCC). How accurate is RCM to predict whether a BCC is infiltrative or ...
- 10.1k
3
votes
0
answers
26
views
What percentage of facial basal cell carcinomas (BCC) are superficial or infiltrative?
I read here (mirror):
Superficial basal cell carcinoma: Approximately 10-15% of all BCCs are of this type. This is the most common pattern seen in BCCs of the shoulder.
The solid (nodular) type ...
- 10.1k
0
votes
1
answer
72
views
Why isn't imiquimod cream used prior to performing a biopsy used for suspected facial basal cell carcinomas?
Given a neoplasm of uncertain behavior of skin on a patient's face that is suspected to be a basal cell carcinoma (BCC), the typical first step is to perform a shave biopsy to determine the type of ...
- 10.1k
1
vote
0
answers
23
views
Why may a small basal cell carcinoma (BCC) treated with radiation be much more aggressive than it appears on the surface?
I read on https://www.skincancer.org/blog/ask-the-expert-why-am-i-having-surgery-to-remove-a-small-basal-cell-carcinoma/ (mirror):
In addition, a small BCC in an area previously treated with ...
- 10.1k
0
votes
1
answer
60
views
Do 50% of individuals with a history of BCC will develop another one within 5 years of diagnosis regardless of the age of the individual?
https://skinio.com/education/basal-cell-carcinoma/ (mirror) says:
Patients diagnosed with BCC should be examined by their dermatologist at least twice a year. Remember, 50% of individuals with a ...
- 10.1k
-1
votes
1
answer
29
views
How accurate is dermoscopy to predict if a skin lesion is a basal cell carcinoma (BCC), and if it is, whether it is superficial or aggressive form? [closed]
https://dermnetnz.org/cme/dermoscopy-course/dermoscopy-of-basal-cell-carcinoma/ mentions that one can use dermoscopy to diagnose basal cell carcinoma (BCC) and their subtype (nodular, superficial, etc....
- 10.1k
0
votes
0
answers
47
views
Why isn't Imiquimod Cream 5% recommended for the treatment of superficial basal cell carcinoma located on the face?
I read on Approval Package for Imiquimod Cream, 5% on February 25, 2010 (mirror):
Reference Drug (NDA number): Aldara® (imiquimod) 5% Cream (NDA 20-723), Graceway
Pharmaceuticals. Date of approval: 2/...
- 10.1k
0
votes
0
answers
26
views
How effective is topical fluorouracil to treat facial superficial basal cell carcinoma (BCC) after Imiquimod 5% cream failed to treat it?
Both Imiquimod 5% cream and topical 5-Fluorouracil (5-FU) have been used to treat basal cell carcinoma (BCC) with a fair amount of success (~60 to 90% success rate at 5-year follow-up) {1}.
Imiquimod ...
- 10.1k
0
votes
1
answer
99
views
Which criteria are used to choose whether to perform a shave biopsy or a punch biopsy to diagnose suspected facial basal cell carcinomas?
Given a neoplasm of uncertain behavior of skin on a patient's face that is suspected to be a basal cell carcinoma (BCC), the typical first step is to perform a shave biopsy to determine the type of ...
- 10.1k
0
votes
0
answers
27
views
Should Imiquimod 5% cream be applied 1 cm beyond the target tumor when treating a facial basal cell carcinoma, and if so, why?
I read on https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/20723s016lbl.pdf (mirror):
364 patients with primary superficial basal cell carcinoma (sBCC) were treated with Aldara Cream or ...
- 10.1k
-2
votes
1
answer
99
views
What is the success rate of topical imiquimod 5% cream to treat infiltrative basal cell carcinoma (BCC)?
What is the success rate of topical imiquimod 5% cream (US brand: Aldara) to treat infiltrative basal cell carcinoma (BCC)?
So far I've only found some case study {1} and some study on using topical ...
- 10.1k
0
votes
1
answer
77
views
Is Imiquimod 5% cream (US brand: Aldara) helpful as an adjunctive treatment of a facial basal cell carcinoma (BCC) prior to a Mohs surgery?
I wonder whether Imiquimod 5% cream (US brand: Aldara) is not helpful as an adjunctive treatment of a facial basal cell carcinoma (BCC) prior to a Mohs surgery. Helpful in this context means 1) ...
- 10.1k
1
vote
1
answer
96
views
How frequently does the use of topical fluorouracil cream result in permanent scarring and/or skin discoloration?
I wonder how frequently the use of topical fluorouracil cream results in permanent scarring and/or skin discoloration (e.g., hyper- or hypopigmentation).
What I have found so far doesn't give any ...
- 10.1k
0
votes
1
answer
88
views
How effective is topical fluorouracil to treat facial superficial basal cell carcinoma (BCC)?
I wonder how effective topical fluorouracil is to treat facial superficial basal cell carcinoma (BCC).
What I have found so far doesn't give any source supporting their claims or I cannot access them:
...
- 10.1k
0
votes
1
answer
220
views
How frequently does the use of topical imiquimod result in permanent scarring and/or skin discoloration?
I wonder how frequently the use of topical imiquimod cream results in permanent scarring and/or skin discoloration (e.g., hyper- or hypopigmentation). What I have found so far doesn't give any source ...
- 10.1k
1
vote
1
answer
95
views
Why isn't fine needle aspiration (FNA) biopsy used to diagnose suspected facial basal cell carcinomas?
Given a neoplasm of uncertain behavior of skin on a patient's face that is suspected to be a basal cell carcinoma, the typical first step is to do a shave biopsy to determine the type of basal cell ...
- 10.1k