Questions tagged [antivirals]

Antiviral drugs are a class of medication used for treating viral infections. They are different to antibiotics.

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1answer
254 views

How is Lopinavir + Ritonavir expected to stop COVID-19?

There are four drugs being tested for effectiveness against COVID-19 in the SOLIDARITY trial. Three of them have obvious potential mechanisms of action: Remdesivir is an RNA polymerase inhibitor. ...
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(Why) are there so few studies of ivermectin as an antiviral in animal models?

I've been trying to understand the ivermectin controversy (especially in view of NIH's recent [partial] change of heart). Based on one of the more recent papers (Jans & Wagstaff) which proposes ...
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1answer
130 views

Was KP-1461 found to be not a good drug?

Everything I've been able to find out about the drug (which is a prodrug, I could glean that it becomes KP-1212 inside the cells, in a process involving triphosphorylation) sounds very promising ...
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1answer
121 views

Continuing effectiveness of anti-viral drugs after shingles outbreak

When shingles is treated with famciclovir for a few weeks and the rash disappears but the pain persists, can another course of treatment with famciclovir reduce pain? If not, what other medications ...
2
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1answer
65 views

For Varicella zoster (chicken pox), when are vaccination/antiviral drugs effective?

The UK does not routinely vaccinate its citizens against chickenpox though the info website of the chief healthcare provider acknowledges that vaccinations are available and there are also ...
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Can oseltamivir shorten the duration of COVID-19 and inhibit replication and transmission of the SARS-CoV-2 (2019-nCoV) virus?

Oseltamivir (Tamiflu) is an antiviral medication used to treat and prevent influenza A and influenza B (flu). It is said to reduce symptom duration even when initiated more than 2 days after symptom ...
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1answer
56 views

Are there *in vitro* studies that find ivermectin directly effective against the SARS-CoV-2 spike or its other proteins?

Among the more obscure papers proposing ivermectin as a treatment for Covid-19 there are some that suggest it acts directly by binding to the SARS-CoV-2 spike protein (and other proteins of that virus ...
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1answer
33 views

For the people who are treated with interferons, does this provide them extra protection against corona virus?

It is known that interferon inhibits the viruses replication process. At the same time, they don't give it to people with COVID-19 because we don't want the flu-like symptoms to get worse. How about ...
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1answer
165 views

How effective is oseltamivir when given before symptoms of flu appear?

A day before someone gets symptoms of flu, it can already been detected that the person will get the flu, as the person is already contagious. Would an antiviral like oseltamivir (Tamiflu) then be ...
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1answer
113 views

Could the Cuban coronavirus antiviral be a mass cure for COVID-19?

Sometime around 1981, the Cubans invented an antiviral treatment for coronavirus. What is its relative efficacy against COVID-19? What are the pathways and obstacles for it making its way to being a ...
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Fact check: Was remdesivir treatment associated with a 62% reduction in mortality rate?

On July 10, 2020, Gilead announced remdesivir treatment was associated with significantly improved clinical recovery and a 62 percent reduction in the risk of mortality compared to standard of care......