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According to the research I've done, taking high amounts of vitamin A in animal form can lead to issues (Vitamin A1, retinol). However, the Carotenoid form (ex: beta carotene) seems harmless.

I heard some people can take megadoses of vitamin A regularly, and the only real side-effect is Carotenaemia, which is harmless (and sometimes desired - for fair-skinned people, it acts as a natural tan).

Is there any excessive harm to the liver for chronic use of - say 10,000 IU of beta carotene? How about 100,000 IU of beta carotene?

  • I edited the title to reflect the actual question. Megadoses of vitamin A are definitely harmful, but that's not what you're asking. – Carey Gregory Jul 9 '16 at 14:12
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Drawing on my previous answer about Vitamin A risks, the only known risk of large doses of carotenoids is an increased risk of lung cancer if you smoke or work with asbestos.

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