Vitamin pills are usually taken orally or sublingually. If I crush them inside a blender as a part of a shake, would it compromise their function?

2 Answers 2


Only a study in which someone would put different vitamins in a blender and measure the eventual changes in their activities could answer this question. Everything else is just a guess or estimation.

Next, the question would need to be for a specific vitamin in a specific chemical form and in a specific tablet.

My estimation is that nothing significant would happen. Some vitamins could be partly destroyed by heat, but blending alone does not produce much heat, anyway. Crushing of the tablet could affect the physical composition of the tablet and result in either slightly decreased or increased absorption of the vitamin.

On NutritionData, there is a chart with estimated effects of drying, cooking and freezing on the vitamin content of foods. For example, cooking (it does not say for how long) can destroy 25% of vitamin A, 50% of vitamin C and 70% of folic acid.

I think, in general, blending would not do nearly as much damage as cooking.


From a chemical point of view, no. Vitamins are fairly stable molecules, so they can live into acidic media (like lemon, vitamin C) or other life media which are generally not prone for chemical species stability.

Avoid heating though, this will alter them.

  • What's wrong with freezing?
    – Sparkler
    Commented May 23, 2016 at 13:30
  • Nothing, edited to check error. Commented May 23, 2016 at 13:34
  • 3
    This post has the makings of a very good answer, but here on Health, we strongly encourage using references. They are the only way in which we can tell if information is reliable or not. If you are struggling to find good sources, check out, What are reliable sources? If you want to learn more about our site's stance on answers without references, check out, Should answers without references be immediately deleted? Thanks :)
    – michaelpri
    Commented May 23, 2016 at 23:27
  • 1
    I agree that we need references on Health. However, those are simply basic rules of chemistry. Any undergrad chemistry student can confirm what I said here. About freezing, I asked on chemistry StackExchange in order to be absolutely sure. Commented May 24, 2016 at 7:33
  • Your answer is true, but misleading. Just because the vitamins are not changed, there is no guarantee that they will have the same effect as when taken as whole tablets, because the way something is metabolised depends on microstructure, not just on content.
    – rumtscho
    Commented May 25, 2016 at 10:55

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