Angiotensin II receptor blockers (ARBs) are commonly used to treat hypertension. One of the side effects of these drugs is to raise serum potassium levels. This occurs because ARBs block the effects of angiotensin II on receptors, which leads to reduced aldosterone production. Aldosterone causes retention of sodium and excretion of potassium, thereby lowering serum potassium levels.
My question is whether this effect is immediate or delayed. For example, if a person begins taking an ARB daily, will its effect on potassium levels be the same on day 1 as it will be on day 30?
Assume normal kidney function and no other drugs. If the particular ARB matters, consider losartan.