Why can't Benzoyl Peroxide kill fungi, unlike bactericidal and fungicidal Salicyclic Acid?

Question

Benzoyl peroxide is not an anti-fungal.

Why's Benzoyl Peroxide merely antibacterial, but NOT antifungal? Salicyclic Acid is both antibacterial¹ and antifungal².

¹ Song, Xiaoqiu, Rui Li, Qian Zhang, Shoukui He, and Yifei Wang. 2022. "Antibacterial Effect and Possible Mechanism of Salicylic Acid Microcapsules against Escherichia coli and Staphylococcus aureus" International Journal of Environmental Research and Public Health 19, no. 19: 12761. https://doi.org/10.3390/ijerph191912761

² Bénigne-Ernest Amborabé, Pierrette Fleurat-Lessard, Jean-François Chollet, Gabriel Roblin, Antifungal effects of salicylic acid and other benzoic acid derivatives towards Eutypa lata: structure–activity relationship, Plant Physiology and Biochemistry, Volume 40, Issue 12, 2002, Pages 1051-1060, ISSN 0981-9428, https://doi.org/10.1016/S0981-9428(02)01470-5.

Answer 1

That website is wrong! Many papers proving that Benzoyl Peroxide IS an anti fungal:

• MIC for 5 yeasts,

• MIC for 3 yeasts.

That website ought to have written that benzoyl peroxide can't kill yeast associated with acne.

Either way, differences in cell structure explain the different abilities of an antimicrobial compound being effective against some, but not other, microbes Some antimicrobials target the

• the replicative machinery of eukaryotes specifically,
• peptidoglycan synthesis in bacteria,
• chitin synthesis in yeast,
• lipids, which make gram positive bacteria and some yeast resistant to it.

The acne-causing yeast have some morphological difference which makes them impervious to benzoyl peroxide. I would venture that some sort of difference in the cell wall structure protects this yeast from benzoyl peroxide?