When describing blood substitute's (BS's) made of perfluorocarbons use in clinical trials, one of the most commonly described side effected in the increase risk of stroke in the area were the PFC is being injected.
How do they increase the risk of stroke? In addition, is the increase risk of risk that overwhelming to prevent its adoption use? There are several examples of drugs, such as hormonal or pain relievers/narcotics that increase risk of clotting/stroke, but these are widely sold. BS's are for emergency use, so the usage of the former drugs seems but not the latter seems puzzling.