The cdc published
Severity of Disease Among Adults Hospitalized with Laboratory-Confirmed COVID-19 Before and During the Period of SARS-CoV-2 B.1.617.2 (Delta) Predominance — COVID-NET, 14 States, January–August 2021
i would clear up some data from the table
TABLE. Demographic characteristics and clinical interventions and outcomes among 7,615 nonpregnant adults aged ≥18 years hospitalized with COVID-19,* by vaccination status† and period relative to SARS-CoV-2 B.1.617.2 (Delta) variant predominance
| Weighted % of COVID-19 hospitalizations (95% CI) | | Unvaccinated | | TOTAL | 4,896 | 1,145 | | ICU admission | Pre Delta period | Delta period | p-value | | ≥18 | 20.1 (18.3–21.9) | 22.6 (19.1–26.3) | > 0.99 | |===================================================================| | | Fully vaccinated | | TOTAL | 389 | 393 | | ICU admission | Pre Delta period | Delta period | p-value | | ≥18 | 19.9 (14.2–26.6) | 24.6 (18.2–32.0) | > 0.99 |
My understanding is that
- based on the wide (95% CI) the sample varies and is probably small
- based on the high p-value the findings are not signifikant, could be chance, are of low confidence
Regarding these footnotes
* Data are from a weighted sample of hospitalized nonpregnant adults with completed medical record abstractions and a discharge disposition. Sample sizes presented are unweighted with weighted percentages.
** Total hospitalizations include data from selected counties in all 14 COVID-NET states with vaccination status, including fully vaccinated, partially vaccinated, and unvaccinated adults. As a result, the number of total hospitalizations exceeds the sum of fully vaccinated and unvaccinated adults.
The second footnote ** is clear. what is unclear the meaning of the first *
Is my understanding above regarding sample variation, ci and p-value correct?
What numbers are weighted and which are not?
How are they weighted?
Does 20.1 of unvaccinated ≥18 mean that 20.1% of all unvaccinated hospitalizations did require ICU admission? Would this be n ~ 230 ~ (1,145 * 20.1%)
solved i hope: Does the p-value refer to a line? So pre-delta and delta? It seems that this is the case. My understanding of the footnote †† is that they compared delta with pre-delta and found no significant difference within a group (vaccinated pre vs delta, and unvaccinated pre vs delta)
solved: Which values are compared for the p-value? (see above)
What gives 100%?
Update 1 - regarding p-value
I overlooked a footnote regarding the meaning of p-value††
†† Proportions between the pre-Delta and Delta period were compared with chi-square tests; p-values <0.05 were considered statistically significant, adjusted for multiple comparisons using the Bonferroni correction method
Update 2 - wrong numbers corrected
After the first reply i corrected the number of hospitalized for fully vaccinated