3

If one were to be "fully vaccinated" with 2 doses of the Pfizer for COVID19 and then six months later vaccinate with the Moderna version: What is the word or phrase to indicate such a protocol?

1
  • 2
    Unofficially: "multi-vaxxer".
    – Fizz
    Oct 7 '21 at 16:33
4

The "CombiVacS" trial used the term "heterologous vaccination schedule", and several other papers cited by that one also use "heterologous":


Kardani, K., Bolhassani, A., & Shahbazi, S. (2016). Prime-boost vaccine strategy against viral infections: mechanisms and benefits. Vaccine, 34(4), 413-423.

Logunov, D. Y., Dolzhikova, I. V., Shcheblyakov, D. V., Tukhvatulin, A. I., Zubkova, O. V., Dzharullaeva, A. S., ... & Gam-COVID-Vac Vaccine Trial Group. (2021). Safety and efficacy of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine: an interim analysis of a randomised controlled phase 3 trial in Russia. The Lancet, 397(10275), 671-681.

Shaw, R. H., Stuart, A., Greenland, M., Liu, X., Van-Tam, J. S. N., & Snape, M. D. (2021). Heterologous prime-boost COVID-19 vaccination: initial reactogenicity data. The Lancet, 397(10289), 2043-2046.

Spencer, A. J., McKay, P. F., Belij-Rammerstorfer, S., Ulaszewska, M., Bissett, C. D., Hu, K., ... & Lambe, T. (2021). Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice. Nature communications, 12(1), 1-8.


You'll find similar terminology of older studies regarding other vaccines but I wouldn't guarantee that other descriptions aren't used, as well, using common English language.

Fragapane, E., Gasparini, R., Schioppa, F., Laghi-Pasini, F., Montomoli, E., & Banzhoff, A. (2010). A heterologous MF59-adjuvanted H5N1 prepandemic influenza booster vaccine induces a robust, cross-reactive immune response in adults and the elderly. Clinical and Vaccine Immunology, 17(11), 1817-1819.

Leroux-Roels, I., Roman, F., Forgus, S., Maes, C., De Boever, F., Dramé, M., ... & Leroux-Roels, G. (2010). Priming with AS03A-adjuvanted H5N1 influenza vaccine improves the kinetics, magnitude and durability of the immune response after a heterologous booster vaccination: an open non-randomised extension of a double-blind randomised primary study. Vaccine, 28(3), 849-857.

1

Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Not the answer you're looking for? Browse other questions tagged or ask your own question.