Comparison of the Childhood Autism Rating Scale (CARS) after 2 years of treatment (folinic acid supplementation and correction of abnormal nutrient values) with the CARS at baseline showed better outcomes for children having negative or low FRα antibody titers of the blocking type, up to 0.44 pmol FRα blocked/mL serum, versus the group whose FRα antibody titers were above 0.44. The baseline CARS score increased as a function of the age at which treatment was initiated. The outcome became poorer for the older subgroup of treated autistic children (Figure 3B). This outcome may be further compounded by the presence of maternal and paternal autoantibodies and embryonic exposure to these. Preliminary data suggested that in the event of maternal or parental FRα autoantibodies, the child´s outcome after treatment was also less favorable (Figure 3C).
This stumped me. How can paternal autoantibodies affect the embryo? Isn't this a typo? Maybe there is some indirect way of paternal antibodies affecting the unborn child? I googled but found nothing.