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I am unable to understand the molecular mechanism of hPL induced insulin resistance. Sharing of relevant article/text would be of immense help.

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hPL elevates insulin resistance due to it causes free fatty acid consumption. With this way, the fetus can consump the mother's glucose.

Source: https://www.sciencedirect.com/topics/neuroscience/human-placental-lactogen

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    But how does that explain insulin resistance? What I meant to ask is the molecular mechanism underlying hPL induced insulin resistance. Commented Feb 19, 2021 at 6:32

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