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There is so much arguing over covid-19 vs. influenza. I would like to have some solid data in my hands. Can anyone point to a simple graph of the following? age vs. either CFR or IFR with one line for covid-19 and another for flu.

For covid there is some relevant, possibly-reliable info at Our World in Data, which has data from March (I couldn't find anything more recent, but this is at least something). This is case fatality rate.

For flu, here is a chart on Business Insider from June 23 which cites "Estimated flu cases and deaths from the CDC". I believe the CDC data used is this (for 2018-2019, for example). And the chart shows Deaths/Symptomatic Illnesses. I suppose that ratio corresponds more or less to the infection fatality rate (IFR), or at least the symptomatic infection fatality rate (sIFR?), which is probably the best we can do.

On the covid side of the chart from Business Insider the caption says "Confirmed COVID-19 cases and deaths from CDC". This is kind of vague but it looks like they're comparing apples and oranges -- flu IFR vs. covid CFR -- which is useless.

So my question is, can someone point either to a covid IFR by age or a flu CFR by age so we can make the comparison? IFR vs IFR would be best but in that case I would also like to see at least an attempt to estimate the error bars for IFR for both diseases.

I think such a plot could have a high impact on public understanding of this situation.

Bonus: Is there another plot that compares how transmissible covid is compared to flu? (I'm not sure what the appropriate metric is for transmissibility. R number I guess.)

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  • Welcome to Medical Sciences! Please take the tour and read the help center. For reasons mentioned in this post and in How to Ask, we require some degree of prior research when asking questions. See this list of helpful resources. Please help us to help you and edit your question to provide more information on what you have read on this subject, what made you ask this question, and any problems you are having understanding your research. If you found nothing, what did you Google?
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    Oct 6, 2020 at 15:02
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    Thank you Carey. I have updated the question with some more research and why I am interested in this.
    – Alex
    Oct 6, 2020 at 16:48

1 Answer 1

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Marc Bevand presents this graph of IFR versus age for both COVID-19 and flu:

[https://raw.githubusercontent.com/mbevand/covid19-age-stratified-ifr/master/covid_vs_flu.png]

The sources of data are documented on this github page. There is a summary of the sources in the README file.

Unfortunately, the IFR data in the graph does not come with error bars. However, most of the underlying sources do include error bars. For instance, Table 1 of "Estimates of the severity of coronavirus disease 2019: a model-based analysis", by Verity, et. al. states:

| age group | IFR      | confidence interval |
|-----------+----------+---------------------|
| 0–9       | 0.00161% | (0.000185–0.0249)   |
| 10–19     | 0.00695% | (0.00149–0.0502)    |
| 20–29     | 0.0309%  | (0.0138–0.0923)     |
| 30–39     | 0.0844%  | (0.0408–0.185)      |
| 40–49     | 0.161%   | (0.0764–0.323)      |
| 50–59     | 0.595%   | (0.344–1.28)        |
| 60–69     | 1.93%    | (1.11–3.89)         |
| 70–79     | 4.28%    | (2.45–8.44)         |
| ≥80       | 7.80%    | (3.80–13.3)         |

In contrast, the "US CDC" COVID-19 IFR data are presented as "current best estimates" which do not state confidence intervals.

I found the graph by google searching for "ifr flu by age", and clicking the "Images" link. Sifting through the graphs led to tweets which reference the github page.

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    I worry that if that graph were presented to the general public, the lack of emphasis that this is a log scale would fool them into thinking the disparity is smaller than it is. Oct 12, 2020 at 17:24

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