Lacunar strokes (small-vessel subcortical strokes) are commonly caused by "lipohyalinosis" or "microatheroma"(1). Both mechanisms appear to be related to hypertension and diabetes, but I haven't been able to find a good definition for these terms. What is the difference between these two mechanisms?
Unfortunately this paper titled "Mechanisms in lacunar infarction" doesn't define the terms either...
- Horowitz DR, Tuhrim S, Weinberger JM, Rudolph SH. Mechanisms in lacunar infarction. Stroke. 1992 Mar;23(3):325-7. doi: 10.1161/01.str.23.3.325. PMID: 1542890. https://pubmed.ncbi.nlm.nih.gov/1542890/