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I am currently studying the AST/ALT ratio and its ability to detect hepatitis and cirrhosis.

I read some articles about this topic and they all seem to consider this ratio quite useful, but I also noticed this study saying the opposite: "AST/ALT Ratio ≥1 is not diagnostic of cirrhosis in patients with chronic hepatitis C" (Reedy et al, Digestive Diseases and Sciences, 1998)

What is the current state of the AST/ALT ratio? Is it currently used in clinical settings? Is it considered reliable by phyisicians?

Thanks

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