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Where is the gene 'NKX2-5' located and what is its function? How is it relevant to developmental disorders?

  • I'm no expert and I'm sure you have explored the net, but I wonder whether you have found this site ghr.nlm.nih.gov/gene/NKX2-5 – Mikel Jul 21 '20 at 16:21
  • @Mikel, thank you for that site. – Andrew Jul 21 '20 at 20:40
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In mammalian cells the gene NKX2-5 is found on chromosome 5, more specifically on the long (q) arm of chromosome 5 at position 35.1. (Cytogenetic Location: 5q35.1)

NKX2-5 is ~3,213 nucleotide bases long and is involved in biological processes that give an organism its shape. Disruption of NKX2-5 has proven to cause abnormal heart shape.

More information can be found: here

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