The first vaccines for viral diseases, such as smallpox, were a variety of live, attenuated or dead virus particles. They did not use adjuvants and they were not safe - but, the chance of complications was still lower than the chance of getting a complication from the disease itself.
Is it reasonable to assume that a home-made vaccine for the virus, made at the level of the 19th-beginning of the 20th century (viral material from a person suffering from the virus, its mucus and saliva, dissolved in water, deactivated by ultraviolet and / or boiling, and then applied to the mucosa of the vaccinated person (for example, injecting this mixture into the nose), can in the future, if not protect, then weaken the course of the disease?
