I read the following quote in the textbook Kaplan Biochemistry (2018 edition, page 183):
Transfused blood has lower than expected 2,3 BPG levels, making it less efficient at delivering oxygen to peripheral tissues.
If I think about this, the answer must lie in glycolysis.
Normally if we had collected blood we collect it in fluoride bulb for glucose estimation. However. in transfusion bag we have CPD-A (citrate, phosphate, dextrose, anticoagulant) but none of it would inhibitors of glycolysis,
Why transfused blood has lower 2,3 - BPG levels? Is storing in cold temperatures of transfused blood slows down glycolysis?