I am looking at the T2DM medications specified here and have a few questions about them.
1) Why don't I see drugs like
Troglitazone, Tolazamide, Acarbose, Acetohexamide, Chlorpropramide, Miglitol? Aren't these drugs used to treat diabetes?
2) I see in drug treatment, we have terms like monotherapy (single drug) and combination therapy (multiple drugs). But what is the combination window usually considered for calling a treatment combination therapy?
By combination window, I mean the number of days both Drug 1 and Drug 2 should overlap. For example, let's say Jacky takes Drug A from Jan 1st till Jan 21st. He also takes Drug B from Jan 11th to Jan 21st. We see that there is an overlap of 10 days. Is there any minimum number of days that you look for to call a treatment combination therapy?