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The hypothalamus forms part of the central autonomic network, regulating body homeostasis and controlling pain. What is its role in headaches?

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Hypothalamic activation during migraine attack This study shows that hypothalamus is key as the migraine attack generator. https://doi.org/10.1177/0333102419867280

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The hypothalamus plays important role in migraine, cluster headache, and several other headaches disorders with seasonal or circadian variation. A recent review highlights the topic.

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