The hypothalamus forms part of the central autonomic network, regulating body homeostasis and controlling pain. What is its role in headaches?
This study shows that hypothalamus is key as the migraine attack generator. https://doi.org/10.1177/0333102419867280
The hypothalamus plays important role in migraine, cluster headache, and several other headaches disorders with seasonal or circadian variation. A recent review highlights the topic.