What are normal structures that could be misinterpreted as lacunar strokes on T1 or T2 brain MRI?

Question

Trying to detect lacunar strokes in brain MRI, in T1 they look like a small black hole, whereas in T2 bright-white; located within white matter region.

My question is, are there any structures that can be found in a healthy brain that could look like that, and therefore be confused with a small lesion? (e.g a blood vessel, benign calcifications)

Answer 1

So far I have found Dilated Virchow-Robin (VR) Spaces (a.k.a dilated perivascular spaces) which are not necessarily malign and have pretty much the exact aspect on T1 and T2. Ref: https://pubs.rsna.org/doi/full/10.1148/rg.274065722