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How does a person share a cure for a disease? Through trial and error a normal Joe or Jane Smoe finds a cure to a disease that has no other cure what is the best way to get it validated?

For example, if someone says that they found a treatment for diagnosed psoriatic rash on the legs and it cured it, but that treatment has not been previously known as a treatment for psoriasis, how can one validate it's a real treatment and not a chance?

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  • There seem to be two parts to this question - how do you "validate" a cure (prove that it does indeed work), and how do you make its use widespread after it's approved by the local regulatory agency. Those are two very different processes. Commented Jun 17, 2019 at 14:35
  • Please clarify who you're trying to validate this treatment with. Are you asking how to submit for regulatory approval or are you asking how to prove this treatment works on you or some other individual?
    – Carey Gregory
    Commented Jun 17, 2019 at 19:07
  • @CareyGregory yes you are correct on both? Should I ask my local dermatologist for help with this?
    – Muze
    Commented Jun 17, 2019 at 19:12
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    Asking how to obtain FDA approval would be on topic here, but that's something far beyond the reach of a layman unless you happen to have millions of dollars to hire expert consultants and fund all the necessary studies and clinical trials it would require. Asking how to prove it works on yourself isn't exactly off topic, but it's borderline. In any case, Jan has provided an answer for that. If you have questions about how to use this treatment, if it's safe, etc, that's definitely off topic and a question for your dermatologist.
    – Carey Gregory
    Commented Jun 17, 2019 at 19:44
  • @CareyGregory understood. TKS
    – Muze
    Commented Jun 17, 2019 at 19:57

2 Answers 2

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If an average Joe and Jane Smoe think they discovered a treatment that works for them but it's not currently used by conventional medicine and they want to validate it for effectiveness and safety, they can ask an experienced doctor, in case of psoriasis a dermatologist, for an opinion. The doctor can then judge if the treatment deserves further investigations and find experts who would be willing to do them. In the US, it's the Food and Drug Administration's (FDA) Center for Drug Evaluation and Research (CDER) who makes the final validation and approval of a treatment:

Drug companies seeking to sell a drug in the United States must first test it. The company then sends CDER the evidence from these tests to prove the drug is safe and effective for its intended use. A team of CDER physicians, statisticians, chemists, pharmacologists, and other scientists reviews the company's data and proposed labeling. If this independent and unbiased review establishes that a drug's health benefits outweigh its known risks, the drug is approved for sale.

The best way to evaluate the effectiveness of treatment is by randomized double blind placebo controlled studies.

Randomized means that a group of participants is randomly divided into 2 groups: the main group receieves the studied treatment and the control group a placebo (the treatment with no effect).

Double-blinded means that during the study neither the researchers nor the participants know who receives the real treatment and who a placebo.

The results of individual studies can be further evaluated by systematic reviews and meta-analyses, which are considered the highest level of evidence.

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    While that's all true, it doesn't touch on the hard part of the question, which is how an average individual would be able to conduct a clinical trial. It seems exceedingly unlikely that would be possible.
    – Carey Gregory
    Commented Jun 17, 2019 at 14:43
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    To me, the core of the question is how to validate the cure, not how to share it. If you just want to share a cure with someone, you simply tell him how it helped you. Or publish an article about it.
    – Jan
    Commented Jun 17, 2019 at 14:45
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    Jan, I agree, but that's the heart of my comment. OP specifically states "normal Joe or Jane," implying someone who is not affiliated with a research institute, hospital, etc. How could they possibly launch a clinical trial?
    – Carey Gregory
    Commented Jun 17, 2019 at 14:52
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    @Jan One person trying a treatment is nothing more than anecdote.
    – Carey Gregory
    Commented Jun 17, 2019 at 16:32
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    I figured that "how to share a cure" means how can an average Joe who thinks he invented a new treatment get this treatment evaluated for safety and effectiveness by experts, so I edited my answer accordingly.
    – Jan
    Commented Jun 18, 2019 at 6:36
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The concepts of disease and cure are part of our medical systems. Disease is not well defined. Cure is less well defined. It is also important to understand that if or when a single case of a disease is found, by Joe and Jane Smoe, to be cured, it does not mean that "the disease" is cured. Only the single case was cured.

A case of disease is cured by addressing its present cause. For example, we can cure many specific infectious diseases caused by a bacterial infection, a fungal infection, or a viral infection by surgically removing the infected tissue, or by a specific medicine that kills or disables the infectious agent. This is the standard definition of cure in today's medical systems. However, the "disease" is not cured, only the specific case. Every infection might be caused by one (or more) infectious agents - and different cures will work on different infections that might appear similar. Every cause of a disease (infectious or not) might be addressed by many different curative actions. Diseases like "influenza" "arthritis" and "cancer" consist of a wide variety of individual cases, each with individual causes. Even when a case has a single cause, it still has many potential cures.

Joe and Jane might find cures. That's not difficult. Most illnesses are minor, and easily cured. Proving the cure (of a case of any non-infectious disease) is simply impossible in the current medical paradigm. It gets worse. It is not even possible to prove that a case of infectious disease was cured by a non-approved treatment. The test for cured, in modern medicine, requires either a clinical study - not just a single case, or an approved medicine. Doctors can claim that a non-approved treatment caused a cure. Nobody cares. It cannot be officially recognized, much less proven without general definitions of cured and cured by. Today, we simply do not have such a definition. Most cures cannot be recognized. No doctor, medical clinic, hospital, medical system, or insurance system counts cures. Treatments are billed. Cures are not billed.

Sharing information about the cure that has been found is not a problem. Sharing a book about the cure is possible, but the publisher might insist on a standard disclaimer like "this book is not intended to cure any disease." Sharing an unapproved cure product is generally considered illegal. It is not legal, for example, to market (probably not even to give away) Vitamin C supplements with the intention to CURE any disease. No medical reference text prescribes Vitamin C as a "cure" for scurvy, it is documented as a "treatment." There are claims, for example, that high doses of Vitamin C, over a period of a few weeks will cure many cases of hypertension - high blood pressure. But, the treatment is not approved, and hypertension cured is not medically defined.

For example, Hopkin's Medicine advises, "Doctors don't know what causes psoriatic arthritis. But factors such as immunity, genes, and the environment may play a role."

Proving a cure requires proof that the cause has been successfully addressed. It thus requires agreement on the cause in the specific case. Modern medicine generally ignores specific cases.

When a case of disease like psoriatic arthritis rash is cured - it's easy for the medical system to assume that the diagnosis was wrong, and move on. Doctors often respond with statements like "I don't know what you are doing, but keep doing it." It's much more difficult to study and understand, much less promote or share the cure. Individual doctors can and often do find many specific cures in their own practice and experience, but sharing them could lead to accusations of quackery (at best) or a threat to their license to practice medicine, or even legal action.

Note: that my original answer to this question was flagged as "that looks like spam." I do not know the cause of that flag, but I simply removed some content and it passed. I stated above, talking about cure "could lead to accusations of quackery" - or of spam.

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    This does not appear to address the question asked.
    – Bryan Krause
    Commented Jul 10 at 20:27
  • Anyone can flag a post as spam; that doesn't mean it is. I'd ask for supporting sources, but the answer doesn't meet the model of this site and you've already been gracious enough to post an answer. (Agree with the quackery comment, btw. There have been times I've told someone that if they tell anyone I recommended (x which was strange), I'd deny it. :)) Commented Jul 11 at 0:32

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