Most daily multivitamins have close to 100% of the RDA for each element in the vitamin, and I believe that the nutrients get into your blood in a short time frame.
Does this daily spike in vitamins have any known health consequences? It would seem more natural to have them split up into smaller doses and be taken with meals each day.
For example, in Japan many vitamins are smaller and designed to be taken a few times over the course of a day. The one-a-day approach most Americans use seems arbitrary and makes me wonder, for example, why we don't take one bigger vitamin every three days (let me ignore the problem of forgetting the day on which we last took vitamins even though it is important here).
So are there any health consequences to taking a single multivitamin once a day? Or is a split approach more conducive to absorption and utilization? At what frequency will vitamin blood concentrations start to have unhealthy spikes?