"Resistance" means refusal to accept or to comply. "Insulin resistance" seems to be a loss of efficiency or efficacy of insulin in the body --- or perhaps an excess of glucose in the blood creating problems for the body to absorb sugar and turn it into energy.

As you can see, I don't know what is insulin resistance and I also can never relate the word resistance when I look up definitions for "insulin resistance".

  • 1
    These seems more like a language question than a medical sciences one. There isn't a specific terminology issue here, it's the plain meaning of the word, you've just focused down on one definition of the word "resistance" rather than reading an entire dictionary definition.
    – Bryan Krause
    Apr 8, 2019 at 14:45
  • Would the definition "the ability not to be affected by something, especially adversely" of "resistance" be the appropriate one for "insulin resistance"?
    – user16007
    Apr 8, 2019 at 15:04
  • 1
    More simply just "less affected by something."
    – Bryan Krause
    Apr 8, 2019 at 15:05

1 Answer 1


Insulin resistance refers to decreased ability of insulin receptors in the cell membranes to respond to insulin.

Insulin resistance (Wikipedia):

Insulin resistance implies that the body's cells (primarily muscle) lose sensitivity to insulin, a hormone secreted by the pancreas to promote glucose utilization. At the molecular level, a cell senses insulin through insulin receptors...

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