Is there a condition which describes an abnormal shrinkage of the eyeball?
That is, a counterpart to buphthalmos (an abnormal enlargement of the eyeball).
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Atrophia bulbi (with shrinkage)
It occurs with shrinkage and also without shrinkage. In without shrinkage, generally the eye is of normal size, but the globe can be enlarged due to glaucoma. In with shrinkage, the globe becomes soft,small and partially collapsed. Atrophy is present in the intraocular tissues but the relationship between the tissues are relatively intact.The horizontal and verical rectal muscles are pulled off which gives the globe a cuboid-like appearance rather than a spherical one. The intraocular pressure (IOP) is decreased. The anterior chamber collapses and the cornea becomes edematous and opacified.
It is also called as atrophia bulbi with disorganization. The globe becomes small, mostly under an average diameter of 16-19 mm(noraml is 24-26 mm). The sclera becomes thickened and the cornea is opacified. Intraocular ossification(bone-formation) may also occur. The bowman layer, lens and retina are calcified. Proliferation and metaplasia of the retinal pigment epithelium (RPE) leads to drusen formation of the eye.