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Most sleep medications have recommendations for short-term use, yet sometimes they are prescribed over months to years.

According to this source:

You can have problems when you use them longer than 7 to 10 days.

Is there evidence for permanent alteration or damage to the brain with long-term use? For example, can it cause narcolepsy or extreme chronic insomnia? I could see the Z or benzos maybe cause permanent brain damage after an overdose. But what about chronic use at standard dosing?

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  • What has your research shown you so far? Where have you already searched? Please help us to help you. We require some evidence demonstrating independent research of the problem domain has been conducted, and that you will also understand the answer. You may improve your question to comply with site guidelines with an edit and the help of How to Ask. Thanks!
    – LаngLаngС
    Commented May 2, 2018 at 13:36
  • @LangLangC this question seems quite similar to this question I asked. health.stackexchange.com/questions/10764/… I would put a specific medication, but was afraid it may be limiting.
    – William
    Commented May 2, 2018 at 13:44
  • @LangLangC my research has shown virtually no experiments of this length because most studies are short term. Sleep medications are not advised to be taken long term and if you compound the withdrawal it would literally last months.
    – William
    Commented May 2, 2018 at 13:49
  • "Limiting": sometimes small is beautiful. Are you talking valerian, lemon balm, barbiturates, alcohol, hops, cannabis, passionflower, benzodiazepams, Z-meds, Chloral hydrate…? Brains have plasticity, neurons and synapses are adaptive. How they react and change depends.
    – LаngLаngС
    Commented May 2, 2018 at 14:00
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    Good. Talking≠taking. If you focus your edit on benzos and Zs, adding your research about their effects it seems on a good way.
    – LаngLаngС
    Commented May 2, 2018 at 14:09

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