Clindamycinum is an antibiotic used to treat skin and vaginal infections. Can people use Clindamycinum for more than 60 days or will the bacteria become resistant to it?

  • 1
    Welcome to HealthSE, Asogi! Please take the tour and read the help center. Personalised medical advice is off-topic here. You may improve your question to comply with site guidelines with an edit and the help of How to Ask. Thanks! Commented Feb 7, 2018 at 22:35
  • 1
    I edited your question to deal with the issue @LangLangC pointed out.
    – Carey Gregory
    Commented Feb 8, 2018 at 3:51

1 Answer 1


Why do you disbelieve the instructions?

However, with erythromycin, clindamycin, and tetracyclines, the rate of resistance is associated with point mutations in rRNA (Ross et al., 2001). Mutations in the 23SrRNA component of an E. coli equivalent nucleotide bases give varying degrees of resistance to erythromycin and clindamycin. 

So, given prolonged use Propionibacterium acnes in Acne Vulgaris will become resistant to clindamycin. There will be a selection pressure for bacteria that develop the mutation.


Your Answer

By clicking “Post Your Answer”, you agree to our terms of service and acknowledge you have read our privacy policy.

Not the answer you're looking for? Browse other questions tagged or ask your own question.