What are the interactions, if any, and their effects to mood/health/wellness, between Ginkgo Biloba and psychotropics?

I'm interested in answers covering at least these drug types:

  • Selective serotonin reuptake inhibitors (SSRI) - example: Fluoxetine (Prozac)
  • Serotonin–norepinephrine reuptake inhibitors (SNRI) - example: Desvenlafaxine (Pristiq)
  • Dopamine reuptake inhibitors - example: Methylphenidate (Ritalin, Concerta)

Update: I tried using drug interaction checkers, such as that from Medscape, but no interactions are reported. Nevertheless, I've done some online search and found some informal references (aka: Reddit) saying that Ginkgo Biloba is a MAOI (monoamine oxidase inhibitor). It is generally advised not to take other medication such as antidepressants and stimulants if you have been on a MAOI for the past 14 days (or vice versa) due to the increased risk of serotonin syndrome, possibly fatal.

I found one study stating:

Potential interactions with monoamine oxidase inhibitors, alprazolam, haloperidol, warfarin, and nifedipine have been reported in case studies.

It also says that no changes in MAO A or B levels were observed, in one study using positron emission tomography imaging following 1 month of treatment at 120mg/day of Ginkgo Biloba in humans; although this might be due to the comparatively low dosage.

  • 4
    What have you learned so far in your own research? Jul 24 '17 at 13:28
  • 1
    Please see: How do I ask a good question?. If you are not sure how to conduct your own research for a question about pharmacological interactions, say so in your question. Thanks! // P.S. It is an interesting question, I just want to make sure you don't get downvotes or put on hold for not following the guidelines. Jul 24 '17 at 13:49
  • 2
    @MarkDWorthenPsyD Thanks for the friendly heads-up. I'll soon be working to improve the question.
    – Marc.2377
    Jul 25 '17 at 3:49
  • Many drug interaction checkers include supplements. Ex: reference.medscape.com/drug-interactionchecker
    – DoctorWhom
    Jul 26 '17 at 6:53
  • 1
    +1 because this is a good question now that you have added evidence of prior research Jul 29 '18 at 6:55

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