What are the interactions, if any, and their effects to mood/health/wellness, between Ginkgo Biloba and psychotropics?
I'm interested in answers covering at least these drug types:
- Selective serotonin reuptake inhibitors (SSRI) - example: Fluoxetine (Prozac)
- Serotonin–norepinephrine reuptake inhibitors (SNRI) - example: Desvenlafaxine (Pristiq)
- Dopamine reuptake inhibitors - example: Methylphenidate (Ritalin, Concerta)
Update: I tried using drug interaction checkers, such as that from Medscape, but no interactions are reported. Nevertheless, I've done some online search and found some informal references (aka: Reddit) saying that Ginkgo Biloba is a MAOI (monoamine oxidase inhibitor). It is generally advised not to take other medication such as antidepressants and stimulants if you have been on a MAOI for the past 14 days (or vice versa) due to the increased risk of serotonin syndrome, possibly fatal.
I found one study stating:
Potential interactions with monoamine oxidase inhibitors, alprazolam, haloperidol, warfarin, and nifedipine have been reported in case studies.
It also says that no changes in MAO A or B levels were observed, in one study using positron emission tomography imaging following 1 month of treatment at 120mg/day of Ginkgo Biloba in humans; although this might be due to the comparatively low dosage.