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Even if children have a weak immune system and are prone to inffections, it is considered physiological for them to have lymphocytosis. What is the reason for this?

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Such type of relative lymphocytosis may be due to:

1)vaccinations in children

Vaccinations increase the number and the types of antigens available to the developing T-cells for their central tolerance.

Thymus is the centre for central tolerence of the T-cells.The T-cells are so important for the immunity in children because they (memory T-cells)can also trigger the formation of B-cells for humoural immunity.

B-cells,however undergo central tolerance in the bone marrow.[REFERENCE]

2)Thymus activity which is at peak during the period from childhood to puberty.[REFERENCE]

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