Apparently undermethylation can be diagnosed using blood work. I googled it a bit, and what I saw seemed to suggest that it isn't widely accepted in the medical community.

I'm wondering how legitimate this diagnosis is. That's hard to define, but I suppose that would mean "has been discussed in peer-reviewed articles in legitimate journals," among other things.

Also, to clarify: I don't doubt that it's a thing. I guess to put my question even more precisely, it would be "is it considered legitimate to care about it and attach weight to it."

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    The terms you're looking for might be "of clinical significance" "strength of evidence" and "evidence-based." I had to google it because I was surprised to hear the organic chem/epigenetic term used this way. I am NOT well versed in the strength of data about alternative medicine, so I will leave the answer to someone else. I recommend a couple changes to the Q: 1. Define undermethylation using a strong resource. 2. it's better to ask what data supports it rather than asking if something is legit. 3. show examples of the information you found on it to give a starting point. Welcome :)
    – DoctorWhom
    Jul 15 '17 at 4:15
  • Health SE in general does not often discuss alternative medicine topics. Some have large amounts of strong evidence supporting them, others do not, and there are a lot of strong opinions on all sides. Look at this meta: health.meta.stackexchange.com/questions/95/…
    – DoctorWhom
    Jul 15 '17 at 4:19
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    Well, are we sure that it IS alternative medicine (as opposed to mainstream)? That's part of my question.
    – Stephen
    Jul 15 '17 at 4:45

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