Is there any evidence of the risk of GI bleeding when comparing IV vs Oral steroids e.g. hydrocortisone Vs Prednisone Vs dexamethasone. The only information I can find is the following picture from this article: https://www.ncbi.nlm.nih.gov/pubmed/6343871

There appears no comments on this in this article: http://bmjopen.bmj.com/content/4/5/e004587

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There are no randomized controlled trials I am aware of. Pubmed yields nothing. Thinking physiologically, it's likely the same risk. PPI in high risk patient regardless of steroid form.


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